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Prune Extract Concentrate

Also known as: Prune Extract Concentrate, Prune, Dried Plum, Plum Extract, Prunus domestica Extract

Overview

Prune extract concentrate is a dietary supplement derived from dried plums (*Prunus domestica*). It is a rich source of dietary fiber, sorbitol, and polyphenols, contributing to its primary use in promoting digestive health and aiding in weight management. The extract is processed to concentrate these beneficial compounds, offering a convenient alternative to consuming whole prunes. Its high fiber content and sorbitol contribute to its laxative properties, making it effective in relieving constipation. While research supports its benefits for constipation and weight reduction, the quality of evidence varies, with some studies showing significant effects, particularly for constipation relief. Prune extract is generally considered safe for consumption, with mild gastrointestinal discomfort being the most commonly reported side effect.

Benefits

Prune extract concentrate offers several evidence-based benefits. It is particularly effective in relieving constipation by improving stool consistency and frequency, as demonstrated in multiple studies. A meta-analysis indicated that prune consumption leads to a significant reduction in body weight, although its effects on BMI and waist circumference were not significant. Some research suggests potential benefits on lipid profiles, but the evidence is less consistent. Elderly individuals may find prune extract particularly beneficial for managing constipation. The onset of benefits for constipation can typically be observed within one week of regular intake. While the effect size for weight reduction is notable, specific values vary across studies.

How it works

Prune extract concentrate primarily works through its high fiber content, which acts as a bulk-forming laxative. This increases stool frequency and softens stool consistency. Sorbitol, another key component, contributes to its osmotic effects by drawing water into the bowel, further facilitating bowel movements. These actions primarily affect the gastrointestinal system. While specific molecular targets are not well-defined for prune extract, its effects are largely attributed to the physical and chemical properties of its fiber and sorbitol content. The dietary fiber is not absorbed and acts locally in the gut.

Side effects

Prune extract concentrate is generally considered safe, but some side effects may occur. The most common side effect is gastrointestinal discomfort, including bloating and gas, which is primarily due to its high fiber content. Uncommon side effects are not consistently reported. Rare side effects are not well-documented. Prune extract may interact with medications that affect bowel movements or blood sugar levels. Individuals with severe gastrointestinal conditions or those sensitive to sorbitol should exercise caution. Pregnant or breastfeeding women should consult healthcare providers before using prune extract. High doses may exacerbate gastrointestinal side effects. It is important to start with a lower dose to assess tolerance and gradually increase as needed.

Dosage

For constipation relief, a dosage of 100-150 grams of prunes per day is often recommended. While a minimum effective dose is not well-established, typical doses range from 100 to 200 grams of prunes per day. The maximum safe dose is not clearly defined, but high doses may exacerbate gastrointestinal side effects. Prune extract concentrate may be a more convenient alternative to whole prunes for some users. It is best taken with meals to minimize gastrointestinal discomfort. The fiber content is not absorbed but acts locally in the gut. No specific cofactors are required for its action.

FAQs

When is the best time to take prune extract?

Prune extract is best taken with meals to reduce the likelihood of gastrointestinal side effects such as bloating or gas. Consistent daily intake is more effective than sporadic use.

How long does it take to see results from prune extract?

For constipation relief, benefits can typically be observed within one week of regular intake. Weight management effects may take longer and are best achieved as part of a balanced diet and exercise plan.

Is prune extract safe for everyone?

Prune extract is generally safe, but individuals with severe gastrointestinal issues or sorbitol sensitivity should consult healthcare providers before use. Pregnant or breastfeeding women should also seek medical advice.

Can prune extract help with weight loss?

Prune extract may aid in weight management as part of a balanced diet and exercise plan. It is not a quick fix for weight loss, but it can contribute to a feeling of fullness due to its high fiber content.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/39721492/ – A systematic review and meta-analysis of 14 studies found that prune consumption significantly reduces body weight in adults. However, the review noted no significant effects on BMI, waist circumference, or blood pressure. The study's quality was rated as moderate due to heterogeneity among the included studies.
https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.4000 – This study investigates the effects of plum products on lipid profiles in adults. While the research suggests potential benefits, the evidence is less consistent compared to the effects on constipation. The study highlights the need for more focused research specifically on prune extract to confirm these findings.
https://www.medrxiv.org/content/10.1101/2022.01.11.22268876v1.full-text – An 8-week randomized, double-blind, placebo-controlled trial demonstrated that prune intake improves stool consistency and frequency. The study concluded that prunes effectively alleviate symptoms of chronic constipation without causing diarrhea. The high-quality RCT design strengthens the evidence for prune extract's efficacy in constipation relief.
https://www.jnmjournal.org/journal/view.html?doi=10.5056%2Fjnm20210 – This article discusses the benefits of prunes for digestive health, particularly in elderly populations. It highlights the role of prunes in improving bowel function and alleviating constipation. The study emphasizes the importance of dietary interventions like prune consumption for maintaining gastrointestinal health in older adults.
https://nopren.ucsf.edu/sites/g/files/tkssra5936/f/wysiwyg/ONLY_newarticles_11Feb2022_Food.xlsx – This document contains a list of new articles related to food and nutrition, potentially including research on prunes and their health benefits. Further investigation of the articles listed in this document may provide additional insights into the effects of prune extract concentrate.