Pterocarpus Marsupium Extract
Also known as: Vijayasar, Indian Kino Tree, *Pterocarpus marsupium*
Overview
*Pterocarpus marsupium* is a tree indigenous to India and Southeast Asia, recognized for its bark's active compounds, particularly pterostilbene. Traditionally utilized in Ayurvedic medicine, it serves primarily in managing diabetes and providing antioxidant benefits. The extract is rich in polyphenolic compounds, contributing to its antioxidant and anti-inflammatory effects. Despite moderate research maturity, with a mix of clinical trials and varying evidence quality, *Pterocarpus marsupium* shows promise for enhancing metabolic health and managing blood glucose levels. The extract is primarily available in capsule or tablet form and is typically utilized for its therapeutic properties.
Benefits
Research has shown *Pterocarpus marsupium* to be effective in lowering blood glucose levels, particularly in adults with type 2 diabetes, where it functions comparably to standard treatments. Evidence indicates significant blood glucose reduction; however, exact effect sizes may differ across studies. Secondary benefits include antioxidant and anti-inflammatory effects, which, while documented, are less quantified. Longer-term benefits can be seen over several weeks to months, emphasizing the importance of consistent use in conjunction with blood glucose monitoring.
How it works
The mechanism of action involves the activation of antioxidant pathways that influence insulin sensitivity and glucose metabolism. Pterostilbene, a primary compound in *Pterocarpus marsupium*, likely interacts with specific cellular targets involved in oxidative stress and inflammation. These actions help modulate metabolic functions and improve overall cardiovascular health through reducing oxidative damage.
Side effects
*Pterocarpus marsupium* is generally regarded as safe at recommended doses, with no reported serious adverse effects in clinical studies. Common side effects (occurring in over 5% of users) include mild gastrointestinal symptoms, while less common side effects (1-5%) may involve allergic reactions or interactions with diabetes medications. It is advised that pregnant and breastfeeding women avoid this supplement due to insufficient safety data. Special caution is warranted for individuals with diabetes to monitor potential effects on blood sugar levels.
Dosage
The recommended dosage for *Pterocarpus marsupium* typically ranges from 200 to 400 mg per day, often taken in divided doses with meals to enhance absorption. The minimum effective dose has not been firmly established, and while certain studies suggest benefits at 200 mg daily, upper limits remain unverified with doses exceeding 400 mg less frequently studied. Timing considerations and interactions with food may influence bioavailability, necessitating personal adjustments based on therapeutic goals.
FAQs
Should I monitor my blood sugar when using this supplement?
Yes, if you are on diabetes medications, monitor your blood sugar levels regularly to ensure proper management.
Is it safe to take during pregnancy?
It is not recommended during pregnancy or breastfeeding due to a lack of safety data.
What’s the best time to take the supplement?
It is advisable to take *Pterocarpus marsupium* with meals to potentially improve absorption.
Can I use this as a replacement for diabetes medication?
No, it should not replace standard diabetes treatments; consult a healthcare provider for tailored advice.
What are the common side effects?
Common side effects include mild gastrointestinal issues, but serious adverse effects are rare.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/37671486/ – This randomized double-blind placebo-controlled trial assessed the safety of *Pterocarpus marsupium* extract in 60 healthy adults over two months, confirming its safety profile with no significant adverse effects.
- https://www.researchgate.net/publication/279596616_Efficacy_of_vijayasar_Pterocarpus_marsupium_in_the_treatment_of_newly_diagnosed_patients_with_type_2_diabetes_mellitus_A_flexible_dose_double-blind_multicenter_randomized_controlled_trial – This multicenter randomized controlled trial evaluated *Pterocarpus marsupium* in newly diagnosed type 2 diabetes patients and found it effective in lowering blood glucose levels, showing potential as an alternative or adjunct treatment.
- https://www.science.gov/topicpages/n/natural+medicine+research – A review highlighting the roles of natural compounds, including those from *Pterocarpus marsupium*, assessing their health benefits but not focusing specifically on this species.