PURE Caffeine Anhydrous
Also known as: Caffeine, Caffeine Anhydrous, Anhydrous Caffeine, C8H10N4O2
Overview
Caffeine anhydrous is a dehydrated form of caffeine, a naturally occurring stimulant found in coffee beans, tea leaves, and cacao pods. It is commonly used for enhancing alertness, improving athletic performance, and aiding in weight loss. Caffeine anhydrous is chemically identical to regular caffeine but lacks water content, making it more concentrated. Extensive research has been conducted on caffeine's effects, with a focus on its ergogenic properties. The evidence base includes numerous systematic reviews and meta-analyses, providing moderate to high-quality evidence for its effects on exercise performance.
Benefits
Caffeine anhydrous is primarily used to enhance athletic performance, with evidence supporting its ergogenic effects on aerobic endurance, muscle strength, muscle endurance, power, jumping performance, and exercise speed. A meta-analysis showed a significant positive effect on athletic performance (SMD: 0.82; 95% CI: 0.27, 1.37; P = 0.003). It also enhances alertness and may aid in weight loss. Most studies focus on young adults, with limited data on older adults and women. The magnitude of the effect is generally greater for aerobic than anaerobic exercise. Effects typically occur within 30 minutes to 1 hour after ingestion.
How it works
Caffeine acts as an adenosine receptor antagonist, increasing alertness and energy by blocking adenosine's inhibitory effects on neurotransmitter release. It affects the central nervous system, cardiovascular system, and muscle physiology. Its known molecular targets are adenosine receptors (A1 and A2A). Caffeine is rapidly absorbed, with peak plasma concentrations reached within 30 minutes to 1 hour.
Side effects
Generally safe when consumed in moderation, but excessive intake can lead to adverse effects. Common side effects (>5%) include jitters, anxiety, insomnia, increased heart rate, and stomach upset. Uncommon side effects (1-5%) include headaches and dizziness. Rare side effects (<1%) include seizures and heart arrhythmias. Caffeine may interact with certain medications like antidepressants and blood thinners. Contraindications include pregnancy, breastfeeding, and certain medical conditions (e.g., high blood pressure). Children, pregnant women, and individuals with certain health conditions should avoid or limit caffeine intake.
Dosage
The minimum effective dose is typically around 1-2 mg/kg body weight for performance enhancement. Optimal dosage ranges are 2-4 mg/kg body weight for most athletic benefits. The maximum safe dose is generally not to exceed 400 mg per day for healthy adults. It should be ingested 30 minutes to 1 hour before exercise for optimal effects. Caffeine anhydrous is more concentrated than regular caffeine, so dosing should be adjusted accordingly. Absorption is not significantly affected by food intake.
FAQs
How much caffeine is safe?
The maximum safe dose is generally considered to be 400 mg per day for healthy adults. It is crucial to monitor individual tolerance.
When is the best time to take caffeine?
Best taken 30 minutes to 1 hour before exercise to enhance alertness and improve exercise performance.
Is caffeine anhydrous safer than regular caffeine?
Caffeine anhydrous is not inherently safer or more effective than regular caffeine; it is simply more concentrated, requiring careful dosing.
What are the expected results from taking caffeine?
It enhances alertness and improves exercise performance. Excessive intake can lead to serious side effects.
Research Sources
- https://bjsm.bmj.com/content/54/11/681 – This umbrella review of meta-analyses found that caffeine improves aerobic endurance, muscle strength, muscle endurance, power, jumping performance, and exercise speed, primarily in young adults. The review noted limited data on women and older adults, but the included meta-analyses were of moderate to high methodological quality, suggesting robust evidence for these effects.
- https://www.researchgate.net/publication/361504637_Efficacy_of_caffeine_on_athletic_performance_A_systematic_review_and_meta-analysis – This systematic review and meta-analysis demonstrated a significant positive effect of caffeine on athletic performance (SMD: 0.82; 95% CI: 0.27, 1.37; P = 0.003). While specific details such as sample size and population are not available in the search results, the significant SMD indicates a notable enhancement in athletic performance due to caffeine intake.
- https://www.tandfonline.com/doi/full/10.1080/15502783.2024.2323919 – This systematic review and meta-analysis found that caffeine enhances muscle strength and power. Specific details regarding sample size, population, and quality assessment are not available in the search results, but the study indicates a positive impact of caffeine on these aspects of physical performance.
- https://www.verywellfit.com/is-caffeine-anhydrous-the-same-as-caffeine-4161151 – This article provides general information about caffeine anhydrous, explaining that it is a dehydrated form of caffeine and discussing its uses and effects. It serves as a basic educational resource on the topic.
- https://www.medicalnewstoday.com/articles/321947 – This article from Medical News Today discusses the potential benefits and risks of caffeine consumption. It covers various aspects of caffeine, including its effects on health and potential side effects.
