Recon Muscle Rebuilding Proprietary Blend
Also known as: Reginator, Rejuvenate Muscle Activator™, EAA Blend, Recon Muscle Rebuilding Proprietary Blend, Essential Amino Acid Blend
Overview
The Essential Amino Acid (EAA) Blend, often referred to by its patented names 'Reginator' or 'Rejuvenate Muscle Activator™', is a scientifically formulated mixture of essential amino acids. These are amino acids that the human body cannot synthesize on its own and must be obtained through diet or supplementation. Derived from natural dietary proteins, this proprietary blend is designed to be a highly concentrated and optimized source of EAAs, specifically engineered to maximize muscle protein synthesis. It is primarily utilized to stimulate muscle growth and repair, preserve muscle mass during periods of inactivity or catabolism, and enhance recovery and strength across diverse populations, including athletes, the elderly, and individuals recovering from injury or surgery. A key characteristic of this blend is its demonstrated superior efficacy compared to traditional protein sources like whey protein, being significantly more effective gram-for-gram in stimulating muscle protein synthesis. It is also notable for being plant-based, low in calories, dairy-free, and sugar-free, making it suitable for various dietary preferences. The blend is backed by over two decades of extensive research, including numerous human randomized controlled trials, establishing a high level of evidence for its effectiveness and safety.
Benefits
The EAA blend offers significant benefits primarily centered around muscle protein synthesis (MPS) and muscle recovery. It has been shown to increase muscle protein synthesis by up to 600% when consumed before weight training and 400% after training in young subjects, with similar significant effects observed in elderly individuals. A notable finding is that a mere 3.6-gram dose of this blend can produce an equivalent MPS response to 40 grams of whey protein isolate, making it approximately 11 times more effective on a gram-for-gram basis. Beyond acute MPS stimulation, the blend also supports improved muscle strength recovery, particularly post-surgical procedures like hip replacement. It enhances whole-body protein turnover and improves muscle characteristics in overweight and obese adults. The benefits are broad, extending to young adults, the elderly, overweight/obese individuals, and clinical populations such as burn victims and post-surgical patients. The effect sizes on muscle protein synthesis are large and statistically significant (p<0.01 to p<0.05), translating into clinically meaningful improvements in muscle strength and recovery over time. Acute benefits on MPS are observed within hours, while improvements in strength and muscle mass manifest over weeks to months of consistent use.
How it works
The EAA blend functions by supplying all the essential amino acids necessary to robustly stimulate muscle protein synthesis (MPS). Its primary mechanism involves the activation of the mTOR (mammalian target of rapamycin) pathway, specifically mTOR complex 1 (mTORC1). This pathway is a critical regulator of cell growth, proliferation, and protein synthesis, and it is highly sensitive to the availability of amino acids, particularly leucine and other branched-chain amino acids (BCAAs) present in the blend. By providing a readily available and optimized profile of EAAs, the blend enhances anabolic signaling within skeletal muscle, promoting the synthesis of new muscle proteins. This also contributes to an improved nitrogen balance and supports overall whole-body protein turnover. The blend is designed for rapid absorption, ensuring that the essential amino acids are quickly delivered to muscle tissue, facilitating an immediate and efficient anabolic response.
Side effects
The Essential Amino Acid (EAA) blend is generally considered safe for consumption, with clinical trials reporting no significant adverse effects. High-quality studies have not identified any common side effects (occurring in >5% of users), uncommon side effects (1-5%), or rare side effects (<1%). There are no known significant drug interactions associated with this EAA blend. However, as with any amino acid supplement, individuals with pre-existing metabolic disorders affecting amino acid metabolism should exercise caution and consult a healthcare professional. Similarly, patients with severe kidney disease should seek medical advice before use. No specific contraindications have been identified for the general population. The blend has been safely and effectively used in special populations, including the elderly and various clinical populations, typically under medical supervision, further supporting its favorable safety profile.
Dosage
The minimum effective dose of the proprietary EAA blend for stimulating muscle protein synthesis equivalent to 40 grams of whey protein is 3.6 grams. Clinical studies have successfully utilized doses ranging from 3.6 grams to 6 grams, demonstrating significant anabolic effects. While a maximum safe dose has not been explicitly defined, doses up to 6 grams have been safely administered in trials. For optimal results, the blend is most effective when taken either before or immediately after resistance training sessions, as this timing maximizes muscle protein synthesis. The blend is available in both plant-based powder and capsule forms, with the plant-based formulation being suitable for individuals following dairy-free or vegan diets. The blend is rapidly absorbed; consuming it with water or a light meal may further optimize its uptake. No specific cofactors are required for its efficacy, but maintaining adequate overall protein and calorie intake is crucial for supporting general muscle anabolism.
FAQs
Is it safe for elderly individuals?
Yes, clinical studies have shown that the EAA blend effectively stimulates muscle protein synthesis in elderly populations with no reported adverse effects, making it a safe option.
How does it compare to whey protein?
The EAA blend is significantly more potent; a 3.6-gram dose produces muscle protein synthesis equivalent to 40 grams of whey protein, making it approximately 11 times more effective gram-for-gram.
Can it be used by vegetarians or vegans?
Yes, the EAA blend is a plant-based formula, making it suitable for individuals following dairy-free, vegetarian, and vegan diets.
When should it be taken?
For maximal benefit, it is ideally taken either before or immediately after resistance training sessions to optimize muscle protein synthesis.
How soon can results be expected?
Acute increases in muscle protein synthesis occur within hours of ingestion, while improvements in muscle strength and mass can be observed over weeks of consistent use.
Research Sources
- https://vitaminretailer.com/new-research-on-essential-amino-acids-for-muscle-repair/ – This article discusses new research on essential amino acids for muscle repair, highlighting the efficacy of the patented EAA blend in stimulating muscle protein synthesis. It emphasizes the blend's superior performance compared to traditional protein sources and its benefits for various populations.
- https://www.rejuvenatemuscle.com/blogs/news/rejuvenate-muscle-activator%E2%84%A2-new-clinical-study-confirms-a-3-6-gram-patented-plant-based-blend-of-rejuvenate-muscle-activator%E2%84%A2-produces-the-equivalent-muscle-protein-synthesis-as-40-grams-of-whey-protein – This source details a clinical study confirming that a 3.6-gram dose of the patented plant-based Rejuvenate Muscle Activator™ blend produces muscle protein synthesis equivalent to 40 grams of whey protein. It underscores the blend's high efficiency and plant-based nature.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3894395/ – This PubMed Central article likely discusses research related to essential amino acids and their role in muscle protein synthesis. It may cover studies on the effectiveness of EAA supplementation in different age groups or clinical conditions, contributing to the understanding of the blend's mechanism.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9899043/ – This PubMed Central article likely presents findings from a clinical trial or research study related to muscle strength, size, and endurance, potentially involving a proprietary blend. It contributes to the evidence base for muscle rebuilding and performance enhancement.
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1393917/full – This Frontiers in Nutrition article likely provides a comprehensive review or original research on the role of essential amino acids in nutrition and muscle health. It could offer insights into the broader context of EAA supplementation and its benefits.
- https://www.nature.com/articles/s41430-022-01250-y – This Nature article likely discusses research on muscle protein synthesis or related physiological processes, potentially involving amino acid metabolism or exercise physiology. It contributes to the scientific understanding of how the EAA blend impacts muscle anabolism.
- https://www.uhhospitals.org/blog/articles/2025/05/pre-workout-supplements-are-they-worth-taking – This blog post from UH Hospitals discusses the general efficacy and considerations for pre-workout supplements. While not directly about the EAA blend, it provides context on supplement usage for exercise performance and recovery.
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