Red Orange Fruit And Peel Extract
Also known as: Red orange, Blood orange, Citrus sinensis varieties Moro, Citrus sinensis varieties Tarocco, Citrus sinensis varieties Sanguinello, Citrus sinensis (Red Orange Extract)
Overview
Red orange extract is derived from the fruit and peel of specific varieties of *Citrus sinensis*, recognized for their reddish flesh. Rich in flavonoids, particularly naringin and hesperidin, as well as carotenoids and soluble fiber, this extract is celebrated for its potential health benefits. It is widely utilized in dietary supplements and skin care products, primarily for its antioxidant, anti-diabetic, anti-hyperlipidemic, and anti-aging properties. While the current body of research includes systematic reviews indicating positive effects on skin health and metabolic profiles, much of the evidence originates from animal studies, with limited but promising human trials. Therefore, further exploration of its effects in diverse populations is warranted.
Benefits
Red orange extract has several documented benefits. Firstly, it shows anti-aging properties by improving skin conditions; one study reported a significant decrease in skin pigmentation and improved hydration after just 15 days of supplementation. Secondly, it improves glucose and lipid metabolism, showcasing anti-hyperglycemic effects in animal models, potentially benefiting diabetic patients by enhancing insulin sensitivity. Additionally, some evidence suggests it may aid in weight management and exert strong antioxidant effects, though findings vary. While benefits on skin health may surface within weeks, glucose and lipid improvements appear over a longer period.
How it works
The beneficial effects of red orange extract are primarily attributed to its high content of flavonoids like naringin and hesperidin. These compounds enhance insulin sensitivity by promoting insulin receptor expression and GLUT4, aiding glucose metabolism. Its antioxidant properties help protect against oxidative stress and UV-induced damage, benefiting skin health. Through interactions with the endocrine system, it also influences metabolic pathways associated with glucose regulation.
Side effects
Generally, red orange extract is regarded as safe when consumed in moderate quantities. Common side effects, though not frequently reported, might include gastrointestinal discomfort in some individuals. There are no widely documented uncommon or rare side effects. Users should be cautious of potential interactions with diabetes medications due to its glucose metabolism effects and consult healthcare providers if they have citrus allergies or are pregnant or breastfeeding. Special populations such as children, the elderly, and diabetic patients should use this supplement under medical supervision due to limited specific data.
Dosage
The recommended minimum effective dose for skin health is around 100 mg per day. While optimal dosages are not firmly established, ranges from 100 mg to several grams per day have been used in various studies. Although high doses have not been associated with a defined maximum safe dose, caution is advised due to possible gastrointestinal side effects. Consistent daily intake is suggested for maintaining benefits. The extract is commonly available in capsule or tablet form, and bioavailability can vary based on formulation and individual factors.
FAQs
How long does it take to see benefits?
Skin health benefits can be observed within a few weeks, while metabolic benefits may require longer duration.
Are there any interactions with medications?
Potential interactions with diabetes medications exist; monitoring is recommended.
Is it safe for everyone?
It is generally safe, but those with allergies or specific health conditions should consult their healthcare providers.
When should I take it?
Consistent daily intake is recommended for optimal effects.
Does it work for all skin types?
While beneficial for many, individual results may vary, and further research is necessary.
Research Sources
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1232229/full – This meta-analysis reviewed various studies on the effects of fruit extract on skin aging in healthy adults, revealing significant improvements in skin hydration and reduced transcutaneous water loss with the use of red orange extract.
- https://pubmed.ncbi.nlm.nih.gov/24910279/ – A randomized controlled trial demonstrating the protective effects of red orange extract against UV-induced skin damage, reporting significant reductions in skin erythema and pigmentation over a 15-day period.
- https://www.frontiersin.org/journals/sustainable-food-systems/articles/10.3389/fsufs.2022.1003144/full – This systematic review highlighted the biological effects of orange by-products, particularly the benefits related to lipid profiles and glucose levels, based mostly on animal studies but with some human data.
Supplements Containing Red Orange Fruit And Peel Extract
Recommended Articles

Herbal Boosters & COVID-19 Antivirals: Safe Mix?
Herbal supplements may interact with COVID-19 antivirals, requiring careful consideration and further research.

Top Immune Support Ingredients: What Works?
Vitamin D, zinc, and echinacea are key ingredients in immune support supplements, backed by scientific evidence.

Top Anti-Inflammatory Supplement Ingredients
Curcumin, omega-3 fatty acids, CBD, and Vitamin D are proven to effectively reduce chronic inflammation.

Best Supplements for Cortisol Reduction: A Scientific Guide
Adaptogens like Ashwagandha and Rhodiola, along with Phosphatidylserine, are effective in reducing cortisol levels, supported by scientific studies.