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Relora

Also known as: Relora, Stress-reducing supplement, Magnolia officinalis and Phellodendron amurense blend

Overview

Relora is a proprietary blend of extracts derived from the barks of *Magnolia officinalis* and *Phellodendron amurense*. These plants have a history of use in traditional Asian medicine for their calming properties. Relora is primarily marketed as a dietary supplement to reduce stress, anxiety, and cortisol levels, which may indirectly aid in weight management by reducing emotional eating. It is characterized by its potential to modulate stress responses without causing significant adverse effects. While research on Relora is ongoing, current studies suggest potential benefits in alleviating stress and anxiety. It is available in capsule form and is generally considered safe for consumption by healthy adults, although further research is needed to fully understand its long-term effects and potential interactions.

Benefits

Relora has demonstrated potential in reducing cortisol levels and improving mood state parameters, including stress and anxiety, in moderately stressed individuals. Studies have shown an approximate 18% reduction in cortisol levels. It may also provide relief for mild, temporary anxiety, particularly in premenopausal women. Benefits are typically observed over a period of 4-6 weeks. While the effect size for cortisol reduction is notable, more extensive research is needed to confirm its clinical significance across diverse populations. The existing evidence suggests that Relora can be a beneficial supplement for individuals experiencing mild to moderate stress and anxiety.

How it works

Relora is believed to modulate the hypothalamic-pituitary-adrenal (HPA) axis, which plays a central role in the body's stress response. By influencing the HPA axis, Relora may help reduce cortisol production and the perception of stress. While the exact molecular targets are not fully understood, it is thought to interact with stress-related pathways in the endocrine system. This interaction helps to regulate cortisol levels and promote a more balanced stress response. Specific data on the absorption and bioavailability of Relora's active compounds are limited, but its effects on cortisol levels suggest effective interaction with the body's stress response mechanisms.

Side effects

Relora is generally considered safe, with no significant adverse events consistently reported in clinical trials. Common side effects are rare, and there is insufficient data to identify uncommon or rare side effects. However, due to limited research, potential drug interactions are not well-studied, and caution is advised when combining Relora with other medications. While there are no established contraindications, pregnant and lactating women should exercise caution due to limited safety data in these populations. Similarly, use in children and individuals with severe medical conditions should be approached with caution. Overall, Relora appears to have a favorable safety profile, but further research is needed to fully assess its long-term effects and potential risks.

Dosage

The typical dosage of Relora is 250 mg capsules taken three times daily. While the optimal dosage range is not definitively established beyond this, it is the most commonly used and studied dosage. There is no established maximum safe dose, and higher doses have not been extensively evaluated. Consistency in timing is recommended, although the specific timing of doses may not be critical. Capsules are the most common form of Relora. Specific absorption factors are not well-documented, and no required cofactors have been identified. Users should adhere to the recommended dosage and consult with a healthcare professional before exceeding it.

FAQs

Is Relora safe to use?

Relora is generally considered safe, but consult a healthcare professional if you have underlying health conditions or are taking medications. More research is needed to fully understand its long-term effects.

How should I take Relora?

Consistent dosing is recommended for optimal effects. The typical dosage is 250 mg capsules taken three times daily. Follow the instructions on the product label or as directed by your healthcare provider.

How long does it take to see results with Relora?

Users may experience reduced stress and anxiety within a few weeks of consistent use. Individual results may vary, and it is not a cure for chronic anxiety or depression.

Can Relora cure anxiety?

Relora is not a cure for chronic anxiety or depression but may help with mild stress. Consult with a healthcare professional for comprehensive treatment options.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/18426577/ – A 2008 pilot study involving 40 premenopausal women found that Relora reduced temporary anxiety without significant side effects. The study suggests potential benefits for anxiety relief in this population, but the small sample size and short duration limit the generalizability of the findings.
https://pubmed.ncbi.nlm.nih.gov/23924268/ – A 4-week RCT with 56 participants showed that Relora significantly reduced cortisol levels and improved mood state parameters. This study provides evidence for Relora's effectiveness in modulating stress hormones and improving mood, but the relatively short duration warrants further investigation into long-term effects.
https://pubmed.ncbi.nlm.nih.gov/30844537/ – This study investigates the effects of *Magnolia officinalis* extract, a component of Relora, on stress and sleep quality. The findings suggest that *Magnolia officinalis* may contribute to stress reduction, which aligns with the reported benefits of Relora.
https://pubmed.ncbi.nlm.nih.gov/36259545/ – This study examines the impact of *Phellodendron amurense*, another component of Relora, on various health outcomes. The results indicate potential benefits related to inflammation and metabolic health, which may indirectly support the overall effects of Relora.
https://www.keystonerx.com/products – This is a product page for a supplement containing Relora. It provides information on the supplement's intended use for stress relief and relaxation, aligning with the general understanding of Relora's benefits.