Royal Agaricus Mushroom Fruiting Body Extract
Also known as: Agaricus blazei Murill, Royal Agaricus, Royal Sun Mushroom, Agaricus brasiliensis
Overview
Agaricus brasiliensis, commonly known as Royal Agaricus or Royal Sun Mushroom, is an edible mushroom native to Brazil, revered for its potential health benefits. This medicinal mushroom is particularly rich in bioactive compounds like β-glucans and phenolic substances, which are thought to contribute to its immunomodulatory and antioxidant properties. Research on A. brasiliensis is moderate, consisting of several clinical trials that explore its effects on immune function and oxidative stress, although there are limited systematic reviews to comprehensively evaluate its efficacy. The mushroom is commonly consumed in supplement form, such as capsules or tablets, making it accessible for those interested in its health-promoting properties. However, the available evidence shows variability in quality, indicating the need for further investigation.
Benefits
The primary benefits of Agaricus brasiliensis include immunomodulation and antioxidant activity. Research suggests that supplementation may enhance immune response, particularly increasing natural killer cell activity, thereby supporting overall immune function. Additionally, the extract has demonstrated potential antioxidant abilities by reducing oxidative stress markers. Secondary benefits include possible support for cancer patients through the reduction of chemotherapy side effects and improvement in metabolic health, particularly insulin sensitivity in those with type 2 diabetes. However, evidence strength varies, with more robust findings surrounding immune enhancement than metabolic effects. More research is necessary to determine exact effect sizes and long-term benefits when used over weeks to months.
How it works
Agaricus brasiliensis exerts its effects primarily through the stimulation of the immune system and the reduction of oxidative stress. The key mechanisms involve the action of β-glucans, which activate various immune cells and enhance their ability to combat pathogens. Additionally, phenolic compounds present in the mushroom contribute to its antioxidant effects by scavenging reactive oxygen species and modulating pathways involved in inflammation. Through these biological interactions, A. brasiliensis supports the body's natural defenses and mitigates oxidative damage.
Side effects
Agaricus brasiliensis is generally considered safe for consumption, with few consistently reported side effects. Common side effects are not well-documented, and only rare adverse effects have been noted. Nonetheless, caution is advised when used alongside immunosuppressive medications or anticoagulants. Individuals with bleeding disorders or those who are immunocompromised should consult a healthcare provider before starting supplementation. Pregnant or breastfeeding women are also advised to seek medical guidance due to the limited research on safety in these populations. Overall, while adverse reactions are rare, monitoring for interactions is prudent.
Dosage
The optimal dosage range for Agaricus brasiliensis is not firmly established, with recommendations typically falling between 300 mg to several grams per day. Some studies indicate high doses, such as up to 9000 mg/day, without significant adverse effects. However, clarity on safety thresholds is lacking. No specific timing for administration is recommended, and the most common forms are capsules or tablets. Bioavailability can vary depending on the extraction method used, but there are no established co-factors required for effective absorption. Therefore, users should start with lower doses and monitor their response to avoid potential overconsumption.
FAQs
What should I consider before starting Agaricus brasiliensis?
Consult a healthcare provider if you're on medications, especially immunosuppressants or anticoagulants.
How safe is Agaricus brasiliensis?
While generally safe, it's important to monitor for potential interactions and consult a healthcare provider if you have health concerns.
Is there a specific time to take Agaricus brasiliensis?
No specific timing is recommended; follow your supplement guidelines.
What results can I expect from taking this supplement?
Users often report enhanced immune function and antioxidant benefits, though individual results may vary.
Is Agaricus brasiliensis a cure for diseases?
No, it supports health but is not a cure for any diseases.
Research Sources
- https://namyco.org/publications/mcilvainea-journal-of-american-amateur-mycology/three-popular-medicinal-mushroom-supplements-a-review-of-human-clinical-trials/ – This review discusses the outcomes of clinical trials on various medicinal mushroom supplements, including A. brasiliensis, highlighting immunomodulatory effects and additional health benefits noted in patients.
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01238/full – A study examining the immunomodulatory and antioxidant effects of aqueous extract of A. brasiliensis in septic mice demonstrated improvements in survival and inflammation markers.
- https://dsld.od.nih.gov/ingredient/Royal+Sun+Mushroom+Fruiting+Body+Extract – This resource provides insights into the uses of Royal Sun Mushroom, summarizing studies that indicate its potential health benefits and noting the need for more comprehensive research.