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Sage Oil Powder

Also known as: Sage, Common Sage, Garden Sage, Dalmatian Sage, Salvia, Salvia officinalis

Overview

Sage, derived from the leaves of *Salvia officinalis* and other *Salvia* species, is an herbal supplement traditionally used for its cognitive enhancement properties. Rich in polyphenols and terpenoids such as rosmarinic acid, apigenin, and eucalyptol, sage is known for its potential to improve memory, mental clarity, and overall cognitive functions. Available in various forms, including capsules and powders, sage has also demonstrated preliminary evidence of hepatoprotective properties in animal studies. The evidence base regarding its cognitive benefits is moderate but varies in quality, indicating a need for more comprehensive research to validate its efficacy.

Benefits

Sage supplementation has been shown to enhance cognitive functions, notably improving memory retention and reaction time. Research indicates a significant increase in digit span memory scores with a p-value of 0.044. Furthermore, potential liver protective effects have been observed in animal studies. The most robust evidence appears in healthy individuals, showing cognitive enhancement effects typically occurring within hours after ingestion. However, due to variable quality in existing studies, further rigorous clinical trials are necessary to solidify claims surrounding the extent and reliability of these benefits.

How it works

The cognitive effects of sage are believed to arise from the interaction of its active compounds with neurotransmitter systems, particularly through the enhancement of cholinergic function, which is crucial for memory and learning. Sage may inhibit acetylcholinesterase, thereby increasing levels of acetylcholine, although this mechanism requires additional confirmation. Its antioxidant properties may also help mitigate oxidative stress on brain cells, contributing to overall cognitive health, while compounds in sage may have effects on liver function, suggesting broader systemic impacts.

Side effects

Sage is generally recognized as safe when used in recommended doses; however, gastrointestinal issues such as reflux are reported in over 5% of users. Other less common adverse effects include allergic reactions to certain terpenes, which affect approximately 1-5% of users. Rare adverse effects are not well-documented, though caution is advised when combined with anticholinergic medications due to potential interactions. Pregnant and breastfeeding individuals should avoid sage due to insufficient safety data. Additional care is necessary for those with epilepsy or specific health conditions, underscoring the importance of individualized monitoring.

Dosage

The recommended dosage of sage extract typically ranges from 300-600 mg, with studies indicating that 600 mg is often associated with positive cognitive outcomes. Users are advised to take sage about two hours before engaging in mentally demanding tasks for optimal results. Care should be taken not to exceed higher doses, as the maximum safe dosage has not been firmly established. Encapsulated forms of sage may enhance absorption, whereas factors like acacia gum may protect against degradation. Individual variability in response to sage supplementation is also noted.

FAQs

How should sage be taken for best results?

Sage is best taken about two hours before cognitive tasks to maximize its beneficial effects.

Are there safety concerns with sage supplementation?

Yes, sage should not be used during pregnancy or breastfeeding, and caution is recommended for individuals with epilepsy.

What effects can I expect from sage supplementation?

Users may experience improved cognitive function, particularly enhanced memory and faster reaction times, within hours of ingestion.

Is sage a replacement for medical treatment of cognitive disorders?

No, sage should not be considered a substitute for medical treatment for cognitive disorders.

What quality control measures should I consider with sage products?

Ensure proper identification of sage species and choose products from reputable suppliers to avoid contamination.

Research Sources

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492021/ – This study explores the cognitive enhancing effects of sage, particularly its impact on memory retention and reaction time. It includes a randomized controlled trial design and discusses the implications for future research in cognitive health.
  • https://www.frontiersin.org/articles/10.3389/fnut.2021.632707/full – A systematic review on the efficacy of various *Salvia* species, focusing on their potential health benefits, including hepatoprotective and cognitive-enhancing properties. It underlines the need for consistency in research methodologies.
  • https://www.sciencedirect.com/science/article/pii/S0140673616309163 – The article presents a meta-analysis of the cognitive effects of herbal supplements, specifically highlighting the role of sage. It evaluates the quality of evidence across studies and suggests recommendations for future research.

Supplements Containing Sage Oil Powder

Elder-C by North American Herb & Spice
68

Elder-C

North American Herb & Spice

Score: 68/100
OregaRESP by North American Herb & Spice
63

OregaRESP

North American Herb & Spice

Score: 63/100
Elderberry-Plus by Physician's Strength
70

Elderberry-Plus

Physician's Strength

Score: 70/100
Oregacillin™ MULTIPLE SPICE EXTRACT DOCTOR'S FORMULA by PHYSICIAN'S STRENGTH®
63

Oregacillin™ MULTIPLE SPICE EXTRACT DOCTOR'S FORMULA

PHYSICIAN'S STRENGTH®

Score: 63/100

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