ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Schisandra Berry Powder

Also known as: Schisandra Berry, Wuweizi, Five Flavor Fruit, Schisandra chinensis

Overview

Schisandra chinensis, commonly known as Schisandra Berry or Wuweizi, is a plant native to East Asia and a staple in traditional Chinese medicine. It's recognized for its adaptogenic properties and unique five-flavor profile (salty, sweet, sour, pungent, and bitter). The berry is rich in bioactive compounds, including lignans, phenolic acids, flavonoids, and triterpenes, which contribute to its various health benefits. Primarily, Schisandra is used to support liver function, enhance cognitive abilities, and improve immune response. It is available in various forms, including powders, capsules, and extracts. While research is growing, more comprehensive studies are needed to fully understand its potential. It is considered a tonic herb, often recommended for long-term use to achieve optimal effects.

Benefits

Schisandra chinensis offers several evidence-based benefits. Studies indicate improvements in liver function markers, such as bilirubin levels and antioxidant capacity, suggesting its potential in supporting liver health. It may also enhance cognitive functions like focus, concentration, and memory. Furthermore, Schisandra supports adrenal function by helping to manage stress through balancing cortisol levels. It also has a positive impact on the immune system, supporting immune function and reducing inflammation. Individuals with metabolic syndrome may benefit from Schisandra's ability to modulate gut microbiota. While these benefits are promising, more extensive research is needed to quantify effect sizes and establish clinical significance.

How it works

Schisandra chinensis exerts its effects through multiple biological pathways. It interacts with neurotransmitter receptors, steroid hormone receptors, and antioxidant pathways, influencing various physiological processes. Specifically, lignans like Schisandrin A, found in Schisandra, may interact with cellular targets involved in liver metabolism, immune function, and cognitive processes. By supporting liver metabolism, Schisandra aids in detoxification and overall liver health. Its impact on the immune system involves modulating immune cell activity and reducing inflammation. Additionally, Schisandra's interaction with neurotransmitter systems may contribute to its cognitive-enhancing effects.

Side effects

Schisandra chinensis is generally considered safe for long-term use, but some side effects should be noted. Common side effects are rarely reported, but may include mild gastrointestinal upset. Uncommon and rare side effects are not well-documented, highlighting the need for more comprehensive safety studies. Potential drug interactions exist, particularly with medications affecting liver metabolism or immune function. Schisandra is contraindicated during pregnancy and breastfeeding due to a lack of safety data in these populations. Caution is advised for individuals with severe liver or kidney disease. It is important to start with a low dose and monitor for any adverse reactions, especially when combining Schisandra with other medications or supplements.

Dosage

The minimum effective dose of Schisandra chinensis typically starts at 500 mg to 1 g per day. Optimal dosage ranges from 1 to 3 g per day, depending on the form and desired effects. The maximum safe dose is not well-established, so caution is advised beyond 3 g per day. It can be taken at any time of day, but morning intake is often recommended for energy and focus. Freeze-dried or extract forms may offer better bioavailability. Consuming Schisandra with fatty meals may also enhance absorption. There are no specifically identified required cofactors. It is recommended to start with a low dose and gradually increase it while monitoring for any adverse effects.

FAQs

How should I start taking Schisandra?

Begin with a low dose (e.g., 500mg) and monitor for any effects. Consult with a healthcare provider, especially if you are taking other medications.

Is Schisandra safe?

Generally safe, but monitor for gastrointestinal side effects. Avoid during pregnancy and breastfeeding. Consult a healthcare provider if you have liver or kidney issues.

When is the best time to take Schisandra?

Morning intake is recommended for cognitive benefits and energy. However, it can be taken at any time of day. Consistency is key for optimal results.

How long before I see results?

It may take several weeks of consistent use to notice the full effects. Individual responses can vary. Long-term use is often necessary for optimal benefits.

Is Schisandra a quick fix for stress?

No, it's not a quick fix. Long-term use is often necessary for optimal benefits. It works best as part of a holistic approach to stress management.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10408133/ – This systematic review highlights the potential of Schisandra chinensis for enhancing immunity, acting as an antioxidant, and improving cognitive function. The review acknowledges the lack of comprehensive studies using advanced analytical techniques, indicating a need for more in-depth research to validate these findings.
  • https://pubmed.ncbi.nlm.nih.gov/37560060/ – This randomized controlled trial involving 40 subjects with fatty liver disease found that Schisandra extract improved liver function markers and antioxidant capacity. While the study is well-designed, the small sample size and limited duration suggest that larger studies are needed to confirm these results.
  • https://draxe.com/nutrition/schisandra/ – This article provides an overview of Schisandra, highlighting its traditional uses and potential health benefits. It emphasizes the adaptogenic properties of Schisandra and its role in supporting overall well-being, though it lacks specific details on research methodologies.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8843844/ – This pharmacological analysis identifies active compounds in Schisandra and their potential roles in immunity, liver metabolism, and cognitive function. While the analysis provides valuable insights into potential mechanisms, it lacks direct clinical evidence, indicating a need for clinical validation.
  • https://lostempireherbs.com/product/schisandra/ – This is a product page for Schisandra, which provides information on the herb's traditional uses and potential benefits. It highlights the adaptogenic properties of Schisandra and its role in supporting overall well-being, though it lacks specific details on research methodologies.

Supplements Containing Schisandra Berry Powder

OJC Plus Super Formula Organic Juice Cleanse Berry Surprise by Purity Products
83

OJC Plus Super Formula Organic Juice Cleanse Berry Surprise

Purity Products

Score: 83/100
Chris Kilham's Supercharged Ashwagandha by Purity Products
83

Chris Kilham's Supercharged Ashwagandha

Purity Products

Score: 83/100
Chris Kilham's Vital Rejuvenator by Purity Products
78

Chris Kilham's Vital Rejuvenator

Purity Products

Score: 78/100
From The Earth Greens by The Vitamin Shoppe
73

From The Earth Greens

The Vitamin Shoppe

Score: 73/100
From The Earth Greens by The Vitamin Shoppe
80

From The Earth Greens

The Vitamin Shoppe

Score: 80/100
Beauty Dust by Moon Juice
73

Beauty Dust

Moon Juice

Score: 73/100
Beauty Dust Sachets by Moon Juice
65

Beauty Dust Sachets

Moon Juice

Score: 65/100
Cosmic Cocoa by Moon Juice
70

Cosmic Cocoa

Moon Juice

Score: 70/100
Cosmic Matcha by Moon Juice
70

Cosmic Matcha

Moon Juice

Score: 70/100
Dream Dust by Moon Juice
80

Dream Dust

Moon Juice

Score: 80/100
Dream Dust Sachets by Moon Juice
78

Dream Dust Sachets

Moon Juice

Score: 78/100
Schisandra by Moon Juice
80

Schisandra

Moon Juice

Score: 80/100