Serrapeptase
Also known as: Serratiopeptidase, Serratia E-15, serralysin, serratiaprotease, Silk worm enzymes
Overview
Serrapeptase is a proteolytic (protein destroying) enzyme from bacteria native to the digestive system of silkworms. It is the enzyme responsible for dissolving a silkworm’s cocoon. Traditionally, serrapeptase has been used for its anti-inflammatory properties. Today, it is marketed as a joint health supplement. Unfortunately, many studies on serrapeptase were poorly structured, with inadequate control groups. The most recent data suggests that serrapeptase is not a very effective supplement, as far as joint health and inflammation is concerned. Though serrapeptase has been detected in plasma after supplementation, the standard oral dose for serrapeptase is low, which means very little is absorbed through the intestines. This may be one of the reasons serrapeptase is unreliable and not very effective. Serrapeptase has been found to have the ability to liquefy mucus and reduce bacterial biofilms (reducing bacteria’s ability to stick to surfaces and each other). This means serrapeptase may be able to reduce phlegm buildup, nasal discharge, lung symptoms of cystic fibrosis and help other compounds fight bacteria. Additional research is needed to confirm these effects.
Benefits
Serrapeptase works by breaking down proteins in the body, which can help reduce inflammation and pain. It is believed to dissolve dead or damaged tissue and promote healing by reducing swelling and inflammation. The enzyme may also help in the liquefaction of mucus, making it easier to expel from the body.
How it works
Serrapeptase may offer several benefits, including: - Anti-inflammatory effects: It can help reduce inflammation in the body, which may alleviate pain and swelling. - Pain relief: By reducing inflammation, serrapeptase may provide relief from pain associated with conditions like arthritis. - Mucus reduction: It may help liquefy mucus, making it easier to clear from the respiratory system, potentially benefiting those with respiratory conditions. - Support for joint health: Some users take serrapeptase to support joint health and mobility.
Side effects
The standard dose for serrapeptase is 10-60mg. Serrapeptase should be supplemented on an empty stomach, which is 30 minutes before a meal or two hours after a meal, three times a day. Most studies use 10mg of serrapeptase taken every eight hours. More human evidence is needed to determine the optimal dose of serrapeptase. 10mg of serrapeptase is equal to approximately 20,000 enzymatic units.
Dosage
Serrapeptase is generally considered safe for most people when taken at recommended doses. However, some potential side effects may include: - Gastrointestinal issues: Such as nausea, diarrhea, or stomach upset. - Allergic reactions: In rare cases, individuals may experience allergic reactions, including rash or difficulty breathing. - Blood thinning: Serrapeptase may have blood-thinning effects, so individuals on anticoagulant medications should consult a healthcare provider before use.
FAQs
What is Serrapeptase?
Serrapeptase is an enzyme derived from silkworms that has anti-inflammatory effects and can help prevent blood clots.
How should I take Serrapeptase?
Serrapeptase should be taken on an empty stomach, 30 minutes before a meal or two hours after a meal, three times a day.
What are the side effects of Serrapeptase?
Potential side effects may include gastrointestinal issues, allergic reactions, and blood thinning effects.
Is Serrapeptase effective for joint health?
The most recent data suggests that serrapeptase is not a very effective supplement for joint health and inflammation.