Sizeon Proprietary Blend
Also known as: SizeOn, Gaspari Nutrition SizeOn, Intra-workout supplement blend, SizeOn Proprietary Blend
Overview
SizeOn Proprietary Blend is an intra-workout supplement developed by Gaspari Nutrition, designed to enhance athletic performance, endurance, and recovery during exercise. It is primarily a carbohydrate and creatine-based formula, typically containing fast-acting carbohydrates (like trehalose and dextrose), creatine monohydrate, L-leucine, taurine, electrolytes, and B-vitamins. The blend aims to provide immediate energy, support ATP regeneration, stimulate muscle protein synthesis, and maintain hydration. While the individual components are extensively researched, the proprietary blend itself lacks direct peer-reviewed clinical trials, with evidence largely stemming from the known effects of its constituent ingredients and anecdotal user reports. It is intended for consumption during workouts to optimize muscle function and recovery.
Benefits
The benefits of SizeOn Proprietary Blend are largely derived from its well-researched individual components. Creatine monohydrate is a primary component, known to significantly improve strength, power output, and muscle endurance during high-intensity, short-duration activities, with studies showing a 5-15% increase in strength and 1-2 kg lean mass gain. The fast-acting carbohydrates (approximately 40g per serving) are crucial for maintaining blood glucose levels, delaying fatigue, and improving endurance performance by an average of 2-3% during prolonged exercise. L-leucine, an essential amino acid, is included to stimulate muscle protein synthesis (MPS) via the mTOR pathway, which is vital for muscle repair and growth. Taurine contributes to electrolyte regulation and hydration, potentially reducing muscle cramping and supporting overall muscle function. B-vitamins further support energy metabolism. These benefits are particularly relevant for athletes engaged in resistance training or endurance sports, aiming to enhance intra-workout energy, performance, and accelerate recovery.
How it works
SizeOn Proprietary Blend works through the synergistic actions of its key ingredients. Creatine monohydrate increases the muscle's phosphocreatine stores, which are critical for rapidly regenerating adenosine triphosphate (ATP), the primary energy currency for high-intensity muscle contractions. The blend's high carbohydrate content provides readily available glucose, which fuels working muscles, spares muscle glycogen stores, and maintains stable blood glucose levels throughout exercise. L-leucine, a branched-chain amino acid, plays a pivotal role in activating the mammalian target of rapamycin (mTOR) signaling pathway, which is a key regulator of muscle protein synthesis, thereby initiating muscle repair and growth. Taurine contributes to cellular osmoregulation and electrolyte balance, supporting proper hydration and muscle contractility. These combined mechanisms aim to optimize energy production, reduce fatigue, and promote muscle recovery during and after intense physical activity.
Side effects
SizeOn Proprietary Blend, composed of generally safe ingredients, typically presents a low risk of adverse effects when consumed as directed. The most common side effects are mild and often related to the creatine and carbohydrate components. These can include minor gastrointestinal discomfort, such as bloating, stomach upset, or diarrhea, particularly if consumed in large quantities or by individuals sensitive to high carbohydrate loads. Creatine can also cause water retention, leading to a slight increase in body weight. While rare, insufficient electrolyte intake alongside high carbohydrate consumption could theoretically lead to mild dehydration. There are no significant drug interactions reported for healthy individuals, but caution is advised for those with pre-existing kidney conditions, as creatine metabolism involves the kidneys. Individuals with kidney disease or metabolic disorders should consult a physician before use. Pregnant or breastfeeding women and children should avoid this supplement or seek medical advice due to insufficient safety data in these populations.
Dosage
The optimal dosage for SizeOn Proprietary Blend is typically one serving (approximately 63g of the blend) mixed with water, consumed during workouts. This serving provides around 40g of carbohydrates, 7g of protein (including leucine), and an unspecified amount of creatine. For creatine monohydrate, an effective daily dose is generally 3-5g, which accumulates in the muscles over days to weeks. Leucine is effective at doses of 2-4g per serving for stimulating muscle protein synthesis. Carbohydrate intake during prolonged exercise is often recommended at 30-60g per hour, which aligns with the product's carbohydrate content per serving. The timing is critical: it is designed as an intra-workout supplement to sustain energy, hydration, and initiate recovery. Co-ingestion of carbohydrates is known to enhance creatine uptake. Adequate water intake is essential to support the absorption and efficacy of the ingredients, particularly creatine and taurine. While individual ingredients have higher maximum safe doses (e.g., creatine up to 20g/day for short-term loading, taurine up to 3g/day), adherence to the product's recommended serving size is advised for the blend.
FAQs
Is SizeOn more effective than creatine alone?
No independent clinical trials confirm SizeOn's superiority over creatine alone. Its benefits likely stem from the combined effects of creatine, carbohydrates, and amino acids, offering a more comprehensive intra-workout support.
Does SizeOn significantly improve muscle pumps?
Anecdotal reports suggest mild improvements in muscle pumps, but SizeOn is not primarily formulated as a nitric oxide booster and may not provide the same level of pump enhancement as dedicated products.
Is it safe to take SizeOn daily?
Yes, SizeOn is generally safe for daily use within recommended doses for healthy individuals with normal kidney function. Consistent daily intake is beneficial for creatine's effects.
When is the best time to take SizeOn?
SizeOn is specifically designed as an intra-workout supplement. It should be consumed during your workout to provide sustained energy, maintain hydration, and initiate muscle recovery processes.
Will SizeOn reduce muscle soreness?
While the leucine content may aid in muscle protein synthesis and recovery, direct evidence specifically for SizeOn reducing muscle soreness is limited. Its primary role is performance and recovery support during exercise.
Research Sources
- https://www.aminoz.com.au/content/blog/gaspari-sizeon-review/ – This review provides a user-oriented perspective on Gaspari SizeOn, discussing its ingredients and perceived benefits like improved intra-workout energy and endurance. It highlights the blend's composition and general user experience, though it is not a peer-reviewed scientific study.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5920428/ – This source likely refers to a study or review on creatine monohydrate, a key component of SizeOn. It would typically discuss creatine's efficacy in enhancing strength, power, and lean body mass, as well as its safety profile, providing foundational evidence for one of SizeOn's main ingredients.
- https://fitnessinformant.com/muscle-builders/gaspari-nutrition-sizeon-review/ – This review from Fitness Informant offers another consumer-focused evaluation of Gaspari Nutrition SizeOn. It details the product's claims, ingredient profile, and user feedback regarding its effectiveness for muscle building and performance, without providing direct clinical research on the blend itself.
- https://gasparinutrition.com/products/sizeon – This is the official product page for SizeOn from Gaspari Nutrition. It provides the manufacturer's description, marketing claims, and ingredient list for the proprietary blend. This source is useful for understanding the intended use and composition as presented by the brand.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10680183/ – This source likely pertains to research on carbohydrate supplementation during exercise or the role of leucine in muscle protein synthesis. It would offer scientific insights into how these individual components contribute to improved endurance, reduced fatigue, and muscle recovery, supporting the rationale behind SizeOn's formulation.
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