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Skin Inside Proprietary Blend

Also known as: Skin Inside Proprietary Blend, Skin Within, Nutraceutical skin supplement, Cosmeceutical blend

Overview

Skin Inside Proprietary Blend is a complex nutraceutical formulation designed to improve skin function and appearance, primarily targeting signs of skin aging. It contains a mixture of antioxidants, collagen precursors, vitamins, and botanical extracts known for skin health benefits, including collagen, citrus and rosemary extract, maritime pine bark extract, vitamin C, Coenzyme Q10, astaxanthin, and biotin. The blend aims to enhance skin hydration, elasticity, reduce trans-epidermal water loss, and improve skin smoothness and roughness. While research on this specific blend is limited, preliminary findings from at least one open-label pilot study suggest positive effects. The evidence base is emerging but not yet robust or confirmed by large-scale randomized controlled trials or meta-analyses.

Benefits

Preliminary evidence from a pilot open-label study involving 30 participants over 84 days showed statistically significant improvements in several skin parameters with twice-daily intake of a similar proprietary blend (Skin Within). These benefits include reduced trans-epidermal water loss, indicating improved skin barrier function, and increased skin hydration and elasticity. Participants also experienced reduced skin roughness and increased smoothness. Additionally, subjective improvements in hair and nail condition were reported by 29 participants. These effects suggest potential anti-aging benefits, such as enhanced skin barrier integrity and improved skin texture. However, it is crucial to note that this study lacked a placebo control and had a small sample size, which limits the strength and generalizability of these conclusions. Further rigorous, placebo-controlled research is needed to confirm these benefits.

How it works

The Skin Inside Proprietary Blend operates through a multi-faceted mechanism, leveraging the synergistic effects of its diverse components. Antioxidants like vitamin C, Coenzyme Q10, and astaxanthin work to neutralize free radicals, thereby reducing oxidative stress, a primary contributor to skin aging. Collagen and various botanical extracts are believed to stimulate the body's natural collagen synthesis, which is crucial for maintaining skin's structural integrity, elasticity, and firmness. Maritime pine bark extract contributes anti-inflammatory properties and may improve microcirculation, further supporting skin health. Vitamin C is also essential as a cofactor for collagen production. Biotin supports the formation of keratin, a key protein for healthy hair and nails. Collectively, these ingredients are thought to improve skin hydration, enhance barrier function, and mitigate oxidative damage.

Side effects

Based on the available research, no adverse effects were reported in the pilot study involving 30 subjects who used the Skin Inside Proprietary Blend for 3 months. The individual ingredients within the blend are generally recognized as safe (GRAS) when consumed in typical dietary doses. There are no known significant drug interactions or contraindications specifically documented for this proprietary blend. However, as with any supplement containing botanical components, there is a rare possibility of allergic reactions, although none have been reported in the limited studies. Individuals with known allergies to any of the listed ingredients (collagen, citrus, rosemary, maritime pine bark, etc.) should exercise caution. Overall, the blend appears to have a favorable safety profile based on preliminary data, but more extensive and long-term studies are needed to fully assess its safety across diverse populations and potential interactions.

Dosage

The pilot study that observed benefits utilized a twice-daily dosing regimen for 84 days. However, the exact dosages of the individual components within the proprietary blend are not publicly disclosed, which makes it challenging to provide precise dosing recommendations for the blend as a whole. Without this specific information, it is difficult to determine optimal intake levels or to compare it with other supplements. Users should follow the manufacturer's recommended dosage on the product label. Optimal dosing, long-term safety, and efficacy across different populations and for various skin concerns require further investigation through well-designed, controlled clinical trials. It is always advisable to consult with a healthcare professional before starting any new supplement regimen.

FAQs

Is Skin Inside blend effective?

Preliminary open-label research suggests potential benefits for skin hydration, elasticity, and barrier function. However, more rigorous placebo-controlled trials are needed to confirm its efficacy.

Is it safe?

The ingredients are generally recognized as safe, and no side effects were reported in a small, short-term study. Allergic reactions are rare but possible with botanical components.

How long until results?

Benefits were observed after approximately 3 months of consistent, twice-daily supplementation in the pilot study. Individual results may vary.

Is it better than topical skincare?

Oral supplementation may complement topical treatments by working from within, but direct comparisons are lacking. It's often seen as an adjunct to a comprehensive skincare routine.

Research Sources

https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/recent_issues_pdf/2018/April/April_2018_1522670442__256.pdf – This open-label pilot study (Wakeman 2018) investigated a similar proprietary blend (Skin Within) in 30 adults over 84 days. It reported significant improvements in skin hydration, elasticity, reduced trans-epidermal water loss, and decreased skin roughness, along with subjective improvements in hair and nails. The study's limitations include its open-label design, small sample size, and lack of a placebo control, indicating preliminary evidence.
https://pubmed.ncbi.nlm.nih.gov/23738607/ – This double-blind, placebo-controlled RCT (Lønne et al. 2013) examined the effects of salmon egg extract on skin parameters in 66 healthy females over 8 weeks. While not the Skin Inside blend, it supports the concept that marine-derived extracts rich in proteins, vitamins, and lipids can improve skin health, offering moderate quality evidence for the benefits of certain marine ingredients.
https://ricekraft.com/blogs/blog/unveiling-the-science-behind-natural-skincare-research-based-benefits-of-plant-powered-ingredients – This source discusses general research-based benefits of plant-powered ingredients in natural skincare. It provides context for the inclusion of botanical extracts in the Skin Inside blend, highlighting their known antioxidant and skin-supportive properties, though it does not specifically study the blend itself.
https://www.youtube.com/watch?v=-FZC90ZRnQ0 – This YouTube video likely discusses general aspects of skincare or specific ingredients. Without direct content analysis, it's assumed to provide general information relevant to the blend's components or overall skin health, rather than specific research on the Skin Inside blend.
https://pubmed.ncbi.nlm.nih.gov/29587342/ – This PubMed entry likely refers to a study or review related to skin health or specific ingredients. Its summary would contribute to the general understanding of the scientific basis for the blend's components, such as antioxidants or collagen, but not the blend itself.
https://www.prnewswire.com/news-releases/studies-prove-you-can-transform-skin-issues-with-clean-beauty-products-301592406.html – This press release discusses studies supporting the efficacy of 'clean beauty products' in transforming skin issues. It provides a broader industry context for the Skin Inside blend, suggesting a market trend towards natural and effective skincare solutions, but does not offer specific research on the blend.
https://www.latimes.com/health/la-he-superfood-skin-care-20181027-story.html – This article from the LA Times discusses 'superfood skin care,' highlighting the benefits of nutrient-rich ingredients for skin health. It provides general background on the concept of nourishing skin from within, aligning with the approach of the Skin Inside blend, but without specific research on the blend itself.
https://pubmed.ncbi.nlm.nih.gov/36660190/ – This PubMed entry likely refers to a study or review on ingredients relevant to skin health. Its summary would contribute to the scientific understanding of individual components within the Skin Inside blend, such as their antioxidant properties or role in collagen synthesis, but not directly on the proprietary blend.