Slimpro Protein Hydrolysates
Also known as: FPHs, Fish Protein Hydrolysate, Hydrolyzed Fish Protein, Fish Protein Hydrolysates
Overview
Fish Protein Hydrolysates (FPHs) are created through the enzymatic hydrolysis of proteins sourced from fish, typically from fish muscle or by-products like blue whiting (_Micromesistius poutassou_). These hydrolysates are rich in peptides and amino acids, allowing for enhanced bioavailability and efficient absorption due to their partially digested nature. FPHs are utilized primarily for weight management, improving body composition, and supporting muscle health and anabolic processes. Although the existing research on FPHs includes several clinical studies and systematic reviews suggesting moderate maturity, further large-scale studies are needed to determine their long-term benefits and optimal dosing strategies.
Benefits
Evidence-based benefits of FPHs include improved body composition and effective weight management. In a randomized clinical trial, dosages of 1.4 g and 2.8 g demonstrated favorable outcomes in increasing cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) levels. A meta-analysis further highlighted the capability of protein hydrolysate supplementation to significantly enhance fat-free mass and lower body strength in resistance-trained individuals. Secondary advantages involve support for skeletal muscle health, especially beneficial for aging populations, alongside evidence of potential improvements in glycemic control. These findings showcase significant effect sizes, predominantly in fat-free mass and muscle strength.
How it works
FPHs function primarily by stimulating the release of appetite-regulating hormones such as CCK and GLP-1, which contribute to increased satiety and better control of food intake. Additionally, FPHs boost plasma amino acid levels, thereby facilitating muscle protein synthesis. They interact with the gastrointestinal system to enhance nutrient absorption and influence metabolic processes through hormonal pathways. The presence of bioactive peptides in FPHs may also play a role in regulating blood pressure and various metabolic functions, thus contributing to their overall health benefits.
Side effects
FPHs are generally considered safe and well-tolerated; significant adverse effects are not reported in the literature. Common side effects are not observed (>5%), and even less common side effects (1-5%) appear undocumented. There is an absence of evidence indicating rare side effects (<1%) related to FPH supplementation. Importantly, no known significant drug interactions or specific contraindications have been identified. However, individuals with fish allergies should avoid FPHs. Due to limited data available on their use during pregnancy or breastfeeding, it is advisable for these populations to exercise caution.
Dosage
Effective dosages for FPH typically begin at approximately 1.4 g per day, with observed improvements in body composition and other relevant metrics. The optimal dosage range appears to be between 1.4 g and 2.8 g daily; notable benefits have been recorded at both doses without the necessity of exceeding this range. While no maximum safe dosage has been definitively established, amounts up to 2.8 g are well-tolerated by most individuals. FPH is recommended to be consumed with meals for enhanced absorption and can be ingested through capsules or incorporated into food products, with microencapsulation techniques commonly used to improve stability and minimize fish flavor.
FAQs
Are Fish Protein Hydrolysates safe?
FPHs are generally safe for most individuals; however, those with fish allergies should avoid them.
When should I take FPH?
While specific timing is undefined, taking FPH with meals may enhance its absorption and effectiveness.
What benefits should I expect from FPH supplementation?
Expect improvements in body composition and satiety, along with potential support for skeletal muscle health.
Is there a maximum dose for FPH?
Doses up to 2.8 g per day are used safely; higher doses do not provide additional benefits based on current evidence.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365743/ – This systematic review examines the effects of protein hydrolysates, including fish protein, on body composition and metabolic health. Results indicate significant improvements in fat-free mass and muscle strength among resistance-trained individuals, supporting the efficacy of protein hydrolysate supplementation in athletic and aging populations.
- https://pubmed.ncbi.nlm.nih.gov/29092843/ – In this randomized clinical trial, dosages of fish protein hydrolysates were shown to elevate levels of appetite-regulating hormones CCK and GLP-1, proving its effectiveness in weight management strategies. The findings highlight the importance of peptide profiles in enhancing satiety.
