Sophora Japonica Flower Extract
Also known as: Japanese Pagoda Tree, Chinese Scholar Tree, Sophora japonica flower extract, Sophora japonica
Overview
Sophora japonica, commonly known as the Japanese Pagoda Tree, is a deciduous tree native to Asia, particularly China and Japan. Its flower extract is celebrated in traditional medicine for a variety of therapeutic effects, including hemostatic, anti-inflammatory, and antioxidant benefits. It is rich in flavonoids and isoflavonoids, bioactive compounds thought to contribute to its health-promoting properties. In modern usage, this extract is being explored for cognitive support and potential anti-aging applications. Although research is growing, it is currently at a moderate maturity level, with much of the evidence surrounding its efficacy and safety leaving room for further clinical investigations.
Benefits
The primary benefits associated with Sophora japonica flower extract include its anti-inflammatory and antioxidant properties, which may provide cognitive benefits, particularly for older adults experiencing memory complaints. Secondary benefits of its extracts encompass anti-osteoporotic, antiviral, and antibacterial effects. Although specific quantified outcomes remain limited for the flower extract, a randomized controlled trial is underway to assess its cognitive advantages. Current understanding of its effects in these areas indicates a moderate level of evidence, highlighting the need for further high-quality clinical trials.
How it works
Sophora japonica's medicinal effects are largely attributed to its flavonoids and isoflavonoids, which may engage with inflammatory pathways and enhance antioxidant defense mechanisms in the body. The extract potentially exhibits neuroprotective effects through these anti-inflammatory actions, although the exact molecular targets remain unidentified. Limited data exist concerning its absorption and bioavailability, indicating further investigation is warranted.
Side effects
Sophora japonica is generally perceived as safe, especially when used traditionally. However, comprehensive safety data are limited. Common side effects are not well-documented, while gastrointestinal upset or allergic reactions could occur in some individuals, albeit infrequently. There may be potential interactions with anticoagulants due to the extract's hemostatic properties, thus caution is advised for individuals on such medications. Pregnant and breastfeeding women are discouraged from using this extract due to insufficient safety data. Additionally, individuals with bleeding disorders should exercise caution due to a potential increased risk of bleeding.
Dosage
Optimal dosing guidelines for Sophora japonica flower extract have not been firmly established, but studies suggest a range between 1,000 to 1,250 mg per day may be effective. Dosage should be tailored to individual needs and based on the specific formulation used. No specific timing recommendations exist for dosage consumption. Capsules and tablets are the most common forms available, although absorption can vary based on extraction methods. Upper limits for safe dosage have yet to be defined, necessitating careful monitoring of individual responses.
FAQs
Is it safe to use Sophora japonica extract while taking other medications?
It's important to consult a healthcare provider before using it, especially if you're on anticoagulants or other medications to avoid potential interactions.
What are the expected results from using this extract?
Potential benefits include cognitive improvement and anti-inflammatory effects, but individual outcomes may vary significantly.
Can this extract serve as a substitute for medical treatment?
No, Sophora japonica should not be considered a substitute for professional medical treatment or prescribed therapies.
When should I take Sophora japonica extract?
Follow the product guidelines or speak to a healthcare provider for personalized timing and administration advice.
Are there any side effects associated with this extract?
Side effects are not well-documented but may include gastrointestinal upset or allergic reactions; consult your physician for concerns.
Research Sources
- https://bioresources.cnr.ncsu.edu/resources/extraction-and-structural-characterization-of-flavoniods-from-twigs-of-sophora-japonica/ – This study focuses on the extraction methods and structural characterization of flavonoids in Sophora japonica, emphasizing the chemical composition and potential health benefits of these compounds.
- https://pubmed.ncbi.nlm.nih.gov/39741575/ – A randomized controlled trial investigating the cognitive benefits of Sophora japonica extract among 100 adults with memory complaints, awaiting results to clarify its efficacy.
- https://www.researchgate.net/publication/374853991_A_Comprehensive_Review_on_Sophora_japonica_Ethnomedicinal_Phytochemistry_Pharmacological_Aspects – This review outlines the ethnomedicinal uses, phytochemical profiles, and pharmacological aspects of Sophora japonica, providing a comprehensive overview but lacking specific data on flower extracts.
- https://pubmed.ncbi.nlm.nih.gov/27085938/ – An analysis of various studies on Sophora japonica, highlighting key pharmacological properties and areas of therapeutic potential, although it does not specifically examine the flower extract.
- https://www.mdpi.com/1420-3049/27/24/8932 – This article reviews the biological activities of Sophora japonica, reporting on its diverse phytochemicals and highlighting the need for more focused clinical research on the extract.
Supplements Containing Sophora Japonica Flower Extract

Phyto-Caplet
Young Living Essential Oils

NAD+ NICOTINAMIDE RIBOSIDE + Resveratrol
ARETE NUTRA

QUERCETIN BROMELAIN
amazon elements

semaine pms relief capsule Extra Strength
semaine

ToxinPul™ Multi-Function Detox
Researched Nutritionals® solutions for life

NMN+ PIPERINE | QUERCETIN
nutri

NAD+ Booster β-Nicotinamide riboside
Thryve

Quercetin Quercétine
AOR™ Advanced Orthomolecular Research

WHOLE FOOD QUERCETIN
MOXYVITES™ by NutraFitz