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dehydrated Spinach

Also known as: Spinach, dehydrated spinach powder, spinach extract, red spinach powder, Amaranthus dubius, Spinacia oleracea

Overview

Dehydrated spinach is a concentrated form of spinach leaves, available from both common green spinach (*Spinacia oleracea*) and red spinach (*Amaranthus dubius*). It is utilized as a dietary supplement and functional food, primarily for enhancing physical performance, supporting cardiovascular health, providing antioxidant benefits, aiding glycemic control, and promoting satiety. This supplement is rich in nitrates, particularly the red spinach variety, which are precursors to nitric oxide (NO), a molecule crucial for vascular function and exercise performance. It also contains significant amounts of antioxidants (vitamins A, C, E, lutein), folate, and nonheme iron. Research into its effects is moderate, with several randomized controlled trials and at least one systematic review focusing on its impact on physical performance and cardiovascular parameters. While evidence quality is limited by sample sizes and study durations, well-conducted trials exist.

Benefits

Dehydrated spinach extract offers several evidence-based benefits. Primary among these is significant improvement in physical performance parameters, including endurance and fatigue resistance. Studies show that 1-2 g daily supplementation over 1-3 months, particularly with nitrate-rich extracts, enhances performance due to increased nitric oxide production. This benefit is most pronounced in young to middle-aged adults. Additionally, 5 g of spinach extract supplementation has been shown to reduce fasting and postprandial glucose levels in overweight/obese adults, indicating potential for glycemic control. While some studies suggest potential for satiety enhancement through thylakoid membrane proteins, this effect is primarily observed in animal models and requires further human research. Body composition changes have shown mixed results, with some studies reporting no significant impact. The observed improvements in physical performance are statistically significant, though effect sizes can vary, and glucose reductions, while significant, need further clinical evaluation.

How it works

The primary mechanism of action for dehydrated spinach, especially nitrate-rich extracts, involves the conversion of dietary nitrates into nitric oxide (NO) within the body. This process is facilitated by oral microbiota. Nitric oxide is a potent vasodilator, leading to enhanced blood flow, improved muscle oxygenation, and increased mitochondrial efficiency, all of which contribute to better exercise performance and endurance. Spinach also influences the cardiovascular system by regulating blood pressure and the metabolic system through its effects on glucose metabolism. At a molecular level, it activates NO signaling pathways and endothelial nitric oxide synthase (eNOS). Furthermore, thylakoid membrane proteins found in spinach may modulate satiety hormones like cholecystokinin, potentially contributing to feelings of fullness. Nitrate bioavailability is crucial, with powder forms potentially being more effective than capsules due to stability and conversion requirements.

Side effects

Dehydrated spinach extract supplementation is generally considered safe, with no reported complications in randomized controlled trials at doses up to 2 g/day for approximately three months. No common, uncommon, or rare side effects have been documented in high-quality studies. However, caution is advised regarding potential drug interactions, particularly with antihypertensive medications, due to the nitrate content which can affect blood pressure. While no clear contraindications are established, individuals prone to kidney stones should exercise caution due to the oxalate content in spinach, although this has not been specifically studied in dehydrated forms. Data on special populations such as the elderly, children, or individuals with chronic diseases are limited, and further research is needed to assess effects in these groups. Overall, short-term use appears safe, but long-term safety data are still lacking.

Dosage

For physical performance benefits, a minimum effective dose of approximately 1 g/day of nitrate-rich spinach extract is recommended. The optimal dosage range varies from 1-5 g/day, depending on the extract's concentration and the desired outcome (e.g., performance enhancement versus glycemic control). While studies up to 5 g/day have shown safety, the maximum safe dose for long-term use is not well established. Timing of supplementation can be either pre-workout or daily. It is important to avoid antibacterial mouthwashes before dosing, as oral microbiota are essential for the conversion of nitrates to nitric oxide. Powder form is generally preferred over capsules for better nitrate bioavailability. No specific cofactors are identified as required, but overall nutritional status may influence the effectiveness of the supplement. Upper limits and safety thresholds for long-term use require further investigation.

FAQs

Is dehydrated spinach effective for exercise performance?

Yes, evidence supports that nitrate-rich dehydrated spinach extract can improve endurance and reduce fatigue by enhancing nitric oxide production, leading to better muscle oxygenation.

Is dehydrated spinach safe for long-term use?

Short-term use (up to 3 months) appears safe with no reported side effects in studies. However, long-term safety data are currently limited and require further research.

How quickly can I expect to see benefits from dehydrated spinach?

Benefits, particularly for physical performance, are typically observed within a few weeks to a few months of consistent supplementation.

Does cooking affect the benefits of spinach, and can dehydrated spinach replace fresh spinach?

Dehydration concentrates nutrients, and while excessive heat can degrade some vitamins, nitrates are generally stable. Dehydrated spinach can supplement, but fresh spinach offers additional hydration and fiber not present in the dried form.

Are there any specific considerations for taking dehydrated spinach?

To maximize nitrate conversion to nitric oxide, avoid using antibacterial mouthwash around the time of supplementation, as oral bacteria are crucial for this process. Powder form may also be more effective than capsules.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC11845096/ – This systematic review, following PRISMA guidelines, analyzed four randomized controlled trials involving 94 adults. It concluded that spinach extract (1-2 g) significantly improved physical performance parameters without adverse events, though it noted limitations due to small sample sizes and short follow-up periods.
  • https://pubmed.ncbi.nlm.nih.gov/39991395/ – This citation refers to a systematic review of randomized controlled trials on spinach extract's effects on physical performance. It found that spinach extract supplementation significantly improved various performance metrics, attributing these benefits to nitrate-induced nitric oxide production.
  • https://www.drugs.com/npp/spinach.html – This source provides general information on spinach, including its nutritional profile and potential health benefits. It mentions the role of spinach in reducing fasting and postprandial glucose levels, as observed in a double-blind RCT with overweight/obese adults using 5g of spinach extract.
  • https://nutrigardens.com/blogs/blog/red-spinach-powder-facts-and-benefits – This article discusses the facts and benefits of red spinach powder, highlighting its high nitrate content and its role in enhancing nitric oxide production. It suggests that the powder form may be more effective for nitrate bioavailability compared to capsules due to stability and conversion requirements.

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