Spleen Tissue
Also known as: Spleen extract, Spleen tissue extract, Bovine spleen extract, Porcine spleen extract, Spleen Tissue Extract
Overview
Spleen tissue supplements are derived from animal spleens, typically bovine or porcine, and are marketed for their purported health benefits, particularly immune system support. These supplements contain various bioactive compounds thought to stimulate the immune system. However, the scientific evidence supporting their use is limited, with most claims based on traditional or anecdotal evidence. Spleen tissue supplements are available in various forms, such as capsules and tablets. They are used for conditions such as low white blood cell counts, cancer, autoimmune diseases, and infections, although rigorous clinical trials are lacking to substantiate these uses. The quality of available evidence is generally low, highlighting the need for further research to determine their efficacy and safety.
Benefits
The benefits of spleen tissue supplements are not well-established due to a lack of robust clinical data. Some users report improved immune function, but this is largely anecdotal and not supported by high-quality research. There is insufficient evidence to quantify specific benefits or establish population-specific benefits. Effect sizes and clinical significance have not been determined due to the absence of rigorous studies. While some individuals may perceive benefits, these are not consistently demonstrated in scientific literature. Therefore, claims of improved immune function should be viewed with caution.
How it works
Spleen tissue supplements are thought to stimulate the immune system, but the specific biological pathways involved are not well-defined. It is believed that bioactive compounds in the spleen tissue interact with the immune system, potentially influencing immune cell activity. However, the detailed mechanisms of action, including known molecular targets, absorption, and bioavailability, remain unclear. Further research is needed to elucidate how spleen tissue supplements interact with the body and exert their purported effects.
Side effects
Spleen tissue supplements are generally considered safe when used as directed, but long-term safety data are lacking. Common side effects are not well-documented, but potential adverse reactions include allergic reactions and gastrointestinal upset. Drug interactions, particularly with immunosuppressive drugs, are possible but not well-studied. Patients with autoimmune diseases or those taking immunosuppressive medications should exercise caution. Pregnant or breastfeeding women should consult healthcare providers before use. Due to the limited research, rare side effects are unknown, and caution is advised when considering these supplements.
Dosage
The minimum effective dose of spleen tissue supplements has not been established, and optimal dosage ranges vary by product, typically following manufacturer recommendations. The maximum safe dose is not defined. There are no specific timing recommendations, and supplements are commonly available in capsule or tablet form. Absorption factors are unknown, and no required cofactors have been identified. Users should consult healthcare providers before starting spleen tissue supplements, especially if they have underlying health conditions, and follow manufacturer instructions carefully.
FAQs
Should I consult a healthcare provider before taking spleen tissue supplements?
Yes, it is advisable to consult a healthcare provider before starting spleen tissue supplements, especially if you have underlying health conditions or are taking other medications.
Are there any known safety concerns with spleen tissue supplements?
While generally considered safe, long-term effects and interactions are not well-studied. Potential side effects include allergic reactions and gastrointestinal upset. Caution is advised.
What results can I expect from taking spleen tissue supplements?
Expected results are variable, and some users report improved immune function, but this is anecdotal. Strong scientific evidence supporting these claims is lacking.
How should I take spleen tissue supplements?
Follow the manufacturer's instructions on the product label. There are no specific timing recommendations, but consistency is generally recommended for any supplement regimen.
Is there strong scientific evidence supporting the use of spleen tissue supplements?
No, there is a lack of strong scientific evidence supporting the use of spleen tissue supplements. Most information is based on traditional use or low-quality studies.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/28716661/ – This study investigates the clinical significance of accessory spleens, highlighting the importance of understanding splenic tissue in medical contexts. While not directly related to spleen tissue supplements, it underscores the relevance of splenic tissue in various medical conditions. The research provides insights into the prevalence and clinical implications of accessory spleens.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7537354/ – This article discusses the management of splenic injuries, providing insights into the spleen's role in trauma and medical interventions. Although not directly related to spleen tissue supplements, it emphasizes the spleen's importance in medical treatments and the need for careful management of splenic injuries. The study contributes to the understanding of splenic function and its clinical significance.
- https://www.webmd.com/vitamins/ai/ingredientmono-1015/spleen-extract – WebMD notes that spleen extract is used for various conditions but lacks strong scientific evidence to support these uses. It highlights the gap between traditional use and evidence-based medicine, emphasizing the need for rigorous clinical trials to validate the efficacy of spleen extract. The information provided serves as a general overview of spleen extract and its purported benefits.
- https://onlinelibrary.wiley.com/doi/abs/10.1111/ans.15383 – This abstract discusses the effects of a supplement on immune function in dogs. The study investigates the impact of the supplement on immune parameters, providing insights into potential immune-modulating effects. The research contributes to the understanding of how supplements can influence immune responses in animals.
- https://academic.oup.com/cid/article/67/4/562/4868139 – This article discusses the risk of infection after splenectomy. The study highlights the importance of the spleen in immune function and the increased susceptibility to infections following its removal. The research underscores the spleen's role in maintaining immune defense and the potential consequences of its absence.
Supplements Containing Spleen Tissue

TG 100 Natural Glandulars
Allergy Research Group

S Spleen
Systemic Formulas Bio Function

BLDB Tonic
Systemic Formulas Bio Challenge

ACP Vitamin ACP
Systemic Formulas Bio Nutriment

Raw Spleen Glandular 200 mg
Swanson Premium Brand

Adrenal Complex
MBi Nutraceuticals

Hematocrit Complex
MBi Nutraceuticals

Lymph Complex
MBi Nutraceuticals

Spleen-350
MBi Nutraceuticals