Stevia Rebaudiana Extract
Also known as: Stevia rebaudiana, Stevia, Sweet Leaf
Overview
Stevia (*Stevia rebaudiana*) is a perennial shrub native to South America, renowned for its intense sweetness derived from glycosides, notably stevioside. It has a rich history as a natural sweetener and traditional medicine, particularly for managing blood sugar levels. Stevia contains bioactive compounds exhibiting antioxidant, antiproliferative, antimicrobial, and anti-inflammatory properties. It is available in various forms, including whole leaf, extracts, and purified glycosides. While research is ongoing, current evidence supports its health benefits, particularly its antioxidant effects. More rigorous clinical trials are needed to fully understand its potential. Stevia is often used as a sugar substitute in foods and beverages, appealing to those seeking to reduce their caloric intake. Its safety and efficacy have been evaluated by regulatory bodies, generally considering it safe for consumption.
Benefits
Stevia leaf extracts exhibit significant antioxidant activity, protecting against oxidative stress-related diseases. Studies in diabetic rats have shown that stevia extracts can restore oxidative stress markers. Stevia may also help lower blood sugar levels, making it potentially beneficial for individuals with diabetes. As a calorie-free sweetener, it is a popular choice for those aiming to reduce sugar intake and manage weight. Research indicates that stevia's bioactive compounds contribute to these effects, though human clinical trials are needed to confirm the extent and consistency of these benefits. The restoration of oxidative markers ranged from 65% to 85% in animal models.
How it works
Stevia's bioactive compounds, including glycosides and phenolic compounds, contribute to its antioxidant and anti-inflammatory effects. These compounds interact with metabolic pathways, potentially influencing blood sugar regulation and antioxidant defenses. While specific molecular targets are not well-defined, they likely involve pathways related to oxidative stress and inflammation. Stevia glycosides are poorly absorbed but metabolized into more bioavailable forms, allowing them to exert their effects within the body. Further research is needed to fully elucidate the precise mechanisms of action and interactions with various body systems.
Side effects
Stevia is generally considered safe for consumption as a sweetener. However, some individuals may experience gastrointestinal upset. Potential effects on blood pressure and kidney function have been noted in some studies but are not consistently reported. No significant rare side effects have been documented. Stevia may interact with antidiabetic medications due to its blood sugar-lowering effects, requiring careful monitoring for those with diabetes. Pregnant or breastfeeding women should consult healthcare providers before using stevia supplements. While generally safe, long-term effects of high doses are not well-studied, warranting moderation in consumption.
Dosage
Stevia is typically used as a sweetener in small amounts. For potential health benefits beyond sweetening, more research is needed to establish optimal dosage ranges. High doses may cause gastrointestinal upset. No specific timing recommendations exist. Leaf extracts may offer more antioxidant benefits than glycoside isolates. Bioavailability varies based on the form of stevia used. While a maximum safe dose is not clearly defined, moderation is advised. Individuals with diabetes should monitor their blood sugar levels when using stevia. Consult with a healthcare provider for personalized dosage recommendations.
FAQs
How is stevia typically used?
Stevia is commonly used as a sugar substitute in foods and beverages. For potential health benefits, consult with a healthcare provider for personalized advice.
Is stevia safe for everyone?
Stevia is generally safe, but individuals with diabetes should monitor their blood sugar levels. Pregnant or breastfeeding women should consult their healthcare provider.
When is the best time to take stevia?
No specific timing is recommended for stevia consumption. It can be used as a sweetener throughout the day as needed.
What are the expected results from using stevia?
Stevia may help reduce sugar intake and potentially offer antioxidant benefits. It is not a cure for diabetes but may help manage blood sugar levels.
What are some common misconceptions about stevia?
Stevia is often mistaken as a cure for diabetes. While it can help manage blood sugar, it is not a replacement for medical treatment.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/37571265/ – This systematic review and meta-analysis found that stevia leaf extracts restored oxidative stress markers more effectively than pure glycosides in diseased rats. The study suggests that stevia extracts may have protective effects against various diseases due to their superior antioxidant properties compared to isolated glycosides.
- https://www.mdpi.com/2076-3921/13/6/692 – This systematic review and meta-analysis integrated antioxidant activity assays of stevia leaf extracts. The review highlighted the robust antioxidant properties of stevia leaf extracts, particularly in organic extracts, suggesting that the extraction method influences the antioxidant capacity.
- https://www.researchgate.net/publication/234144712_PubMed_ScienceDirect_Scopus_or_Google_Scholar_-_Which_is_the_best_search_engine_for_an_effective_literature_research_in_laser_medicine – This source is a comparison of search engines for literature research and does not provide specific information about Stevia Rebaudiana Extract. Therefore, it is not relevant for summarizing the effects or properties of Stevia.
- https://www.mdpi.com/2072-6643/15/15/3325 – This study investigates the impact of Stevia rebaudiana supplementation on metabolic parameters in overweight/obese individuals. The research explores the potential of stevia to influence body weight, glucose metabolism, and lipid profiles in this population, providing insights into its role in metabolic health.
- https://pubmed.ncbi.nlm.nih.gov/19961353/ – This study demonstrated the antihyperglycemic and antioxidative abilities of stevia leaves in diabetes-induced mice. The findings suggest potential benefits for diabetic patients, indicating that stevia leaves can help manage blood sugar levels and reduce oxidative stress in animal models.
