Superpure Gotu Kola Aerial Extract
Also known as: Gotu Kola, Asiatic Pennywort, Brahmi, Centella asiatica
Overview
Centella asiatica, commonly known as Gotu Kola, is a plant native to Asia and Africa, revered in traditional Ayurvedic medicine. It's primarily used to enhance cognitive function, promote wound healing, and improve skin health. The plant contains triterpenoids, such as asiaticoside and madecassoside, believed to be responsible for its therapeutic effects. While research on Centella asiatica is considered moderate, with some systematic reviews and meta-analyses available, the quality of evidence varies. Some studies suggest promising results, but more rigorous research is needed to confirm its efficacy and safety. It is available in various forms, including capsules, powders, and topical creams, derived from both cultivated and wild-harvested plants.
Benefits
Centella asiatica has shown potential benefits in several areas. A systematic review and meta-analysis indicates that it may improve working memory, although the evidence is not definitive. Studies have also linked its consumption to improved alertness and contentedness, though not necessarily cognitive performance. Additionally, there is evidence suggesting benefits for wound healing and skin health, primarily from animal studies. These benefits may be particularly relevant for elderly populations seeking cognitive support. While effect sizes are generally small to moderate, further research is needed to fully establish the clinical significance and long-term benefits of Centella asiatica.
How it works
Centella asiatica's mechanism of action is primarily attributed to its triterpenoid compounds. These compounds are believed to enhance collagen synthesis, which is crucial for wound healing. They may also improve blood flow, potentially contributing to both wound healing and cognitive effects. The plant interacts with the nervous system, possibly enhancing cognitive function, and with the circulatory system to improve wound healing. At the molecular level, triterpenoids may influence collagen production and neurotrophic factors, though more research is needed to fully understand these interactions.
Side effects
Centella asiatica is generally considered safe when used appropriately, but potential side effects should be considered. Common side effects, reported in rare cases, include gastrointestinal upset. Uncommon side effects, occurring in 1-5% of users, may involve allergic reactions or skin irritation. Rare side effects are not well-documented. It may interact with anticoagulants and diabetes medications due to its effects on blood sugar and clotting. Centella asiatica is contraindicated during pregnancy and breastfeeding due to a lack of safety data. Caution is advised for individuals with diabetes or bleeding disorders. It's important to consult with a healthcare provider before use, especially if you have pre-existing conditions or are taking other medications.
Dosage
The minimum effective dose of Centella asiatica is not well-established, but typical dosages range from 500 mg to 2,000 mg per day. Most studies use doses between 500 mg and 1,500 mg per day. The maximum safe dose is not clearly defined, so caution is advised beyond 2,000 mg per day. There are no specific timing recommendations, but it may be taken with meals to reduce gastrointestinal upset. Extracts may be more effective than raw plant material. Bioavailability may be enhanced with food intake. No specific cofactors are documented. Always start with a lower dose to assess tolerance.
FAQs
Is Centella asiatica safe?
Generally safe, but may interact with certain medications. Consult a healthcare provider before use, especially if you have pre-existing conditions.
When should I take Centella asiatica?
Can be taken with meals to reduce potential gastrointestinal side effects. There are no specific timing recommendations beyond this.
What results can I expect?
May improve mood and alertness within hours; cognitive benefits may take longer. Results vary and it's not a substitute for medical treatment.
Can Centella Asiatica be used to treat medical conditions?
No, it is not a substitute for medical treatment; consult a healthcare provider before use for any health concerns.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/28878245/ – This systematic review and meta-analysis examined the effects of Centella asiatica on cognitive function and mood. The review included five randomized controlled trials and suggested potential benefits for both cognitive function and mood, but noted limitations due to the quality and number of included studies.
- https://www.mdpi.com/1660-4601/19/6/3266 – This study investigates the potential health benefits of Centella asiatica, highlighting its traditional use and bioactive compounds. It emphasizes the need for further research to validate its efficacy and safety for various applications, including cognitive enhancement and wound healing.
- https://www.webmd.com/vitamins/ai/ingredientmono-753/gotu-kola – This WebMD page provides general information about Gotu Kola, including its uses, potential benefits, and safety precautions. It serves as a basic overview for consumers, but lacks the depth of scientific research found in peer-reviewed studies.
- https://www.sciencedirect.com/science/article/pii/S1756464620305612 – This article discusses the potential of Centella asiatica in improving alertness and contentedness, though not necessarily cognitive performance. It highlights the need for more research to fully understand the mechanisms and long-term effects of Centella asiatica on cognitive and psychological well-being.
- https://www.e-jer.org/journal/view.php?number=2013600960 – This meta-analysis explores the effects of Centella asiatica on working memory. While the findings suggest a potential improvement in working memory, the authors caution that the evidence is not robust due to variability in study designs and other methodological limitations.
