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Tongkat Ali Concentrated Extract Complex

Also known as: Tongkat Ali, Malaysian Ginseng, Eurycoma longifolia

Overview

Eurycoma longifolia, commonly known as Tongkat Ali, is a traditional medicinal plant native to Southeast Asia. It is renowned for its use in enhancing male fertility and anti-aging. The plant contains bioactive compounds, particularly quassinoids, that are linked to its pharmacological effects, predominantly in improving libido and testosterone levels. While the research on Tongkat Ali is moderately developed, clinical trials and systematic reviews have begun to demonstrate significant benefits, particularly in populations with low testosterone. The supplement is primarily available in concentrated extract forms, including hot-water extracts which are noted for their efficacy and safety.

Benefits

Tongkat Ali offers several evidence-based benefits, particularly in the enhancement of testosterone levels. A systematic review shows significant increases in testosterone in men, especially those with hypogonadism, with a standardized mean difference (SMD) of 1.352. Daily supplementation has been associated with better stress hormone profiles, reducing cortisol while enhancing testosterone. Secondary benefits include improvements in mood states, such as decreased tension and confusion, and potential enhancements in sleep quality, although these findings require further research. Notably, benefits are particularly prominent in individuals with low testosterone levels and heightened stress, although the overall magnitude of these effects varies and requires additional study for clinical significance.

How it works

Tongkat Ali is thought to influence testosterone bioavailability through its effect on sex hormone-binding globulin (SHBG), which binds to testosterone and prevents it from exerting its effects. By potentially releasing free testosterone from SHBG, Tongkat Ali may increase the levels of bioactive testosterone available in the body. The bioactive compounds, mainly quassinoids, are believed to play a critical role in modulating the endocrine system's response, particularly in managing stress hormones and improving overall mood state.

Side effects

Generally, Tongkat Ali is regarded as safe when consumed at recommended dosages, with no significant adverse effects consistently reported in clinical studies. Some users may experience mild gastrointestinal upset, but such occurrences are rare and not well-documented. There are currently no known serious or rare side effects reported. Nevertheless, caution is encouraged for individuals with severe medical conditions or those on medications. Pregnant or breastfeeding women should avoid Tongkat Ali due to insufficient data regarding safety during these periods. There is limited information available on potential drug interactions, indicating the need for medical consultation prior to use for those on concurrent treatments.

Dosage

The minimum effective dose for Tongkat Ali is typically around 200 mg per day of standardized extract. The recommended dosage range is between 200 to 400 mg daily, with higher doses (>400 mg) not extensively studied for safety and efficacy. No specific timing for administration has been established. Hot-water extract forms are preferred due to their superior safety and effectiveness. Absorption levels may differ based on the extraction method used, though no significant co-factors that influence efficacy have been identified.

FAQs

What should I consider when using Tongkat Ali?

Ensure the supplement is sourced from reputable suppliers and standardized for bioactive compounds to ensure quality.

Is Tongkat Ali safe to use?

Generally safe for most individuals; consult a healthcare provider if you have underlying health conditions.

Is there an optimal time to take Tongkat Ali?

There are no specific timing recommendations for Tongkat Ali supplementation.

How soon can I expect results from Tongkat Ali?

Users typically observe improvements in testosterone levels and stress hormone profiles within weeks of supplementation.

Can Tongkat Ali replace medical treatments?

Tongkat Ali is not a substitute for medical therapies; consult a healthcare provider before starting.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC9415500/ – This systematic review and meta-analysis demonstrated that Tongkat Ali significantly increases testosterone levels in men, particularly those with low testosterone, with a notable effect size. Limitations noted include heterogeneity in study designs, underscoring the need for further research.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC3669033/ – A randomized controlled trial indicated that daily supplementation with Tongkat Ali improves stress hormone profiles and mood states among moderately stressed individuals. However, this study's small sample size suggests further investigation is warranted for robust conclusions.
  • https://academic.oup.com/sleepadvances/article/5/1/zpae047/7710213 – Research in mice suggested that Tongkat Ali supplementation may enhance sleep quality through diurnal rhythm improvements. Its efficacy in humans, however, remains less clear and calls for further clinical validation.