Total Caffeine
Also known as: Caffeine, 1,3,7-Trimethylxanthine, Total Caffeine
Overview
Caffeine is a naturally occurring stimulant found in coffee beans, tea leaves, cacao pods, and guarana seeds. It is widely consumed and used as a dietary supplement to enhance alertness and physical performance. As a central nervous system stimulant, caffeine primarily works by blocking adenosine receptors, which leads to increased alertness and energy levels. It is available in various forms, including capsules, tablets, powders, and beverages. Extensive research supports caffeine's ergogenic effects, though the quality of evidence varies across studies. It is generally considered safe for consumption in moderation, but excessive intake can lead to adverse effects. Caffeine's effects typically begin within 30 minutes of ingestion and can last for several hours, depending on the dosage and individual sensitivity.
Benefits
Caffeine is well-documented for its ergogenic effects, improving aerobic endurance, muscle strength, muscle endurance, power, jumping performance, and exercise speed. A meta-analysis demonstrated that caffeine significantly improves time to exhaustion in running tests. It may also enhance cognitive function and aid in weight loss, although the evidence for these benefits is less consistent. The benefits are generally observed across various populations, with most studies focusing on young adults. The effect size for endurance performance is moderate. Effects typically begin within 30 minutes of ingestion and last for several hours.
How it works
Caffeine primarily acts by blocking adenosine receptors in the brain, which reduces adenosine's inhibitory effects and increases the activity of neurotransmitters like dopamine and norepinephrine. This leads to enhanced alertness, reduced fatigue, and improved cognitive and physical performance. Caffeine affects the central nervous system, cardiovascular system, and metabolic pathways. It is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached within 30 minutes to 1 hour.
Side effects
Common side effects of caffeine consumption include insomnia, jitteriness, anxiety, increased heart rate, and stomach upset. Uncommon side effects may include headaches and dizziness. Rare side effects, such as seizures and arrhythmias, are possible but less frequent. Caffeine may interact with certain medications, such as antidepressants, potentially increasing the risk of side effects. It is contraindicated in individuals who are pregnant, breastfeeding, or have certain cardiovascular conditions. Children, older adults, and individuals with specific medical conditions should limit or avoid caffeine intake. Excessive caffeine intake can lead to more severe adverse effects, so moderation is advised.
Dosage
The minimum effective dose of caffeine is typically around 50-100 mg for cognitive effects and 200-400 mg for physical performance. The optimal dosage range for most adults is 200-400 mg per day. It is generally recommended not to exceed 400 mg per day. Caffeine is best taken 30 minutes to 1 hour before the desired effect. It is available in various forms, including capsules, tablets, and beverages, with absorption being generally consistent across different forms. Individual sensitivity to caffeine varies, so it is advisable to start with a lower dose to assess tolerance.
FAQs
How much caffeine should I take for a workout?
A dose of 200-400mg of caffeine 30-60 minutes before a workout is typically recommended to improve physical performance. Start with a lower dose to assess your tolerance.
When is the best time to take caffeine?
Caffeine is best taken in the morning or early afternoon to avoid sleep disturbances. For exercise, take it 30-60 minutes before your workout.
Is caffeine addictive?
Caffeine can be habit-forming, and withdrawal symptoms like headaches and fatigue can occur upon cessation. Moderation is key to avoiding dependence.
What are the signs of too much caffeine?
Signs of excessive caffeine intake include jitteriness, anxiety, insomnia, rapid heart rate, and stomach upset. Reduce your intake if you experience these symptoms.
Does caffeine provide energy?
Caffeine does not provide energy but rather enhances alertness and performance by masking fatigue. It stimulates the central nervous system, making you feel more alert.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/36615805/ – This meta-analysis examined the effects of caffeine on various aspects of physical performance. The study found that caffeine is ergogenic for aerobic endurance, muscle strength, muscle endurance, power, jumping performance, and exercise speed. The researchers noted variability in study methodologies and outcomes but concluded that caffeine generally enhances physical performance.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9315598/ – This systematic review with meta-analysis examined the acute effects of caffeine supplementation on physical performance. The study supports the use of caffeine as an ergogenic aid. The review highlights the importance of considering individual responses and variations in study designs when interpreting the results.
- https://bjsm.bmj.com/content/54/11/681 – This article summarizes caffeine's effects on various aspects of physical performance, highlighting its ergogenic benefits. It emphasizes that caffeine improves aerobic endurance, muscle strength, muscle endurance, power, jumping performance, and exercise speed. The review underscores the importance of understanding caffeine's mechanisms and individual responses for optimizing its use in sports and exercise.
- https://journals.humankinetics.com/view/journals/ijspp/19/11/article-p1180.xml – This study investigates the impact of caffeine on physical performance, providing insights into its ergogenic effects. The research contributes to the understanding of how caffeine can be used to enhance athletic performance. Further details on the specific findings and methodologies can be found in the full article.
- https://www.bmj.com/content/359/bmj.j5024 – This article discusses the effects of caffeine on health and performance. It provides a comprehensive overview of caffeine's benefits and risks, helping to inform decisions about its consumption. The article emphasizes the importance of moderation and awareness of individual sensitivity to caffeine.
Supplements Containing Total Caffeine

Mayhem Electric Blue Raspberry
Mutant

Mayhem Fruit Punch Frenzy
Mutant
Green Stinger
Schwartz Laboratories

Sustained Energy
NOW Sports

Rush
Gorilla Mind

Rush
Gorilla Mind

AminoLean x Chase Byrd Cherry On Top
RSP

Oxyshred Ghostbusters Slimer Flavor
EHPlabs

Oxyshred Ultra Energy Gummy Snake
EHPlabs

Apex Burn Cherry Blaze
Alpha Lion

Hydroxycut Organic
Hydroxycut

Gorilla Mind Rush
Gorilla Mind
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