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Tribulus Fruit Extract

Also known as: Tribulus terrestris, Tribulus, Gokshura, Puncture Vine

Overview

Tribulus terrestris is a plant found in tropical and temperate regions, with its fruit extract commonly used as a dietary supplement. It contains saponins, flavonoids, and other bioactive compounds. It is often marketed for enhancing testosterone levels, improving sexual function, and supporting athletic performance. However, the evidence supporting these claims is limited and mixed across studies. The quality of available evidence is generally low due to methodological limitations and variability in study designs. While some studies suggest potential benefits, particularly for sexual function in women, the overall research maturity level is still considered preliminary. It is available in various forms, including capsules and tablets, and is sourced from the fruit of the Tribulus terrestris plant.

Benefits

There is no conclusive evidence that Tribulus terrestris significantly increases testosterone levels or improves athletic performance. Some studies suggest potential benefits for sexual function in women, particularly premenopausal women, who may experience improved sexual function scores with supplementation. However, the certainty of this evidence is low. Some studies indicate moderate improvements in lipid profiles and inflammatory markers, but the clinical significance of these effects is generally low due to small sample sizes and methodological limitations. Any potential benefits typically require several weeks to months of supplementation.

How it works

The exact mechanisms of action for Tribulus terrestris are not fully understood. It may influence nitric oxide release, which could explain some of its purported physiological effects. There are potential interactions with the cardiovascular and reproductive systems, though the evidence supporting these interactions is limited. Specific molecular targets and detailed data on absorption and bioavailability are lacking. Further research is needed to elucidate the precise mechanisms by which Tribulus terrestris may exert its effects.

Side effects

Tribulus terrestris is generally considered safe based on available studies, with no reported toxicity. However, common, uncommon, and rare side effects are not well-documented. Potential interactions with blood thinners or diabetes medications exist due to its effects on blood sugar and blood pressure, though these interactions have not been extensively studied. It is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Caution is advised in individuals with diabetes or those taking anticoagulants. Long-term effects are not well-studied, and users should be aware of the limited evidence supporting its benefits.

Dosage

There is no established minimum effective dose for Tribulus terrestris. Typical dosages range from 500 mg to 2000 mg per day, although efficacy is not well-supported by strong evidence. The maximum safe dose is not well-defined. There are no specific timing recommendations for administration. Capsules or tablets are common forms. Absorption factors are not well-studied, and no required cofactors have been established. Users should be aware of the lack of strong evidence supporting its benefits when considering dosage.

FAQs

Does Tribulus terrestris increase testosterone?

No, there is no conclusive evidence that Tribulus terrestris significantly increases testosterone levels in humans. Studies have shown mixed results, and systematic reviews have not found a significant increase.

Is Tribulus terrestris safe?

Tribulus terrestris is generally considered safe based on available studies, but long-term effects are not well-studied. It is contraindicated in pregnancy and breastfeeding. Caution is advised for those with diabetes or taking anticoagulants.

How should I take Tribulus terrestris?

Typical dosages range from 500 mg to 2000 mg per day, but efficacy is not well-supported. There are no specific timing recommendations. Capsules or tablets are common forms. Be aware of the limited evidence supporting its benefits.

What are the expected results from taking Tribulus terrestris?

Benefits are not consistently demonstrated across studies. Some studies suggest potential benefits for sexual function in women, but the certainty of this evidence is low. Do not expect a significant increase in testosterone levels.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/24559105/ – This systematic review of eleven studies, including both human and animal subjects, found no significant increase in testosterone levels in humans when Tribulus terrestris was used as a sole supplement. The review highlighted methodological variability and a lack of meta-analysis, indicating limited evidence quality. These findings suggest that Tribulus terrestris may not be effective for increasing testosterone levels as commonly believed.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9368143/ – This systematic review focused on physically active adults and found no clear benefits of Tribulus terrestris on sport and health biomarkers. The review acknowledged the limited number of studies available and performed a methodological quality assessment to exclude poor studies. The results indicate that Tribulus terrestris may not provide significant benefits for athletic performance or overall health in active individuals.
https://www.mdpi.com/2072-6643/17/7/1275 – This study investigated the effects of Tribulus terrestris on women with sexual dysfunction, finding a significant improvement in sexual function scores in premenopausal women after 1 to 3 months. However, the study noted a low certainty of evidence and assessed the risk of bias using the Cochrane tool. These findings suggest a potential benefit for sexual function in a specific population, but the evidence should be interpreted with caution due to limitations.
https://www.scielo.br/j/rbgo/a/j9q637hwJbhZDWPb8syg83w/ – This systematic review examined the effects of Tribulus terrestris on women with sexual dysfunction. The review found that Tribulus terrestris may improve sexual desire, arousal, and satisfaction in women experiencing sexual dysfunction. However, the authors noted that the overall quality of evidence was low, and further research is needed to confirm these findings.