Tribx90
Also known as: Tribulus terrestris L., Puncture vine, Gokshura, Devil's thorn, Tribx90, Tribulus terrestris
Overview
Tribulus terrestris, commonly known as puncture vine, is an herbal supplement derived from a plant found in arid regions worldwide. It has been traditionally used as an aphrodisiac and adaptogen. Research suggests potential benefits in managing sexual dysfunction and improving sperm parameters, although evidence quality varies. The active components are believed to be steroidal saponins, particularly protodioscin. It is available in various forms, typically as standardized extracts containing 40-60% saponins. While some studies explore its effects on athletic performance and hormonal levels, the results are often inconclusive. Overall, Tribulus terrestris shows promise in specific reproductive applications, but its broad-spectrum performance enhancement claims require cautious interpretation.
Benefits
Tribulus terrestris demonstrates potential benefits, primarily in the areas of sexual function and sperm parameters. Studies indicate a 62.4% improvement in sperm concentration and a 74.2% improvement in sperm motility. For female sexual dysfunction (FSD), research shows significant score improvements, although the evidence certainty is low. While some studies suggest aphrodisiac effects, particularly in rodent models, human data on testosterone increases are inconsistent and often non-significant. Its effectiveness for athletic performance enhancement remains inconclusive, with some studies showing no significant benefits.
How it works
Tribulus terrestris is thought to exert its effects through several mechanisms. The steroidal saponins, particularly protodioscin, are believed to play a key role in modulating physiological processes. It may activate nitric oxide synthase, potentially improving blood flow and sexual function. Additionally, it might sensitize LH receptors, influencing hormone production. However, the bioavailability of its active components is poorly characterized, making it difficult to fully understand its mechanism of action. Standardized extracts typically contain 40-60% saponins, but the specific impact of these compounds on the body requires further investigation.
Side effects
Common side effects of Tribulus terrestris include gastrointestinal discomfort, with an incidence rate of 7-12%. Less common side effects are headaches and restlessness. Rare case reports suggest potential hepatotoxicity. It may interact with antihypertensive and anticoagulant medications, so caution is advised when taken with these drugs. Tribulus terrestris is contraindicated during pregnancy due to its uterotonic effects observed in vitro. It's important to note that long-term safety data is limited, and users should be aware of potential risks before use.
Dosage
The effective dosage range for Tribulus terrestris is typically between 250-1500mg per day, standardized to contain 40-60% saponins. For improving sexual function, a dosage of 750mg twice daily has been used in human studies. The maximum safe dosage is considered to be 1500mg per day, although long-term data is limited. It is recommended to take Tribulus terrestris with meals to enhance the absorption of its lipid-soluble components. Individual responses may vary, and it's advisable to start with a lower dose and gradually increase as needed.
FAQs
Does it boost testosterone?
Human data on Tribulus terrestris and testosterone levels are inconsistent. Most randomized controlled trials (RCTs) show only minor, non-significant increases in testosterone.
How long until results?
For improvements in sexual function, effects may be noticeable within 4-12 weeks. For spermatogenesis, allow at least 12 weeks of consistent use before assessing results.
Suitable for women?
Tribulus terrestris shows promise for female sexual dysfunction (FSD) but requires medical supervision due to potential hormonal effects and limited long-term safety data.
Research Sources
- https://onlinelibrary.wiley.com/doi/10.1155/2023/7118431 – This systematic review and meta-analysis of 30 studies (133 humans and 476 rodents) investigated the effects of Tribulus terrestris. The findings indicated robust spermatogenic effects but limited hormonal impact. The authors noted high heterogeneity among the included studies, which may limit the generalizability of the findings.
- https://www.scielo.br/j/rbgo/a/j9q637hwJbhZDWPb8syg83w/ – This Cochrane-style systematic review analyzed 5 RCTs involving 279 women to assess the impact of Tribulus terrestris on female sexual dysfunction (FSD). The review found improved sexual scores, but the certainty of the evidence was rated as low. The authors also noted the short duration (≤3 months) of the included studies as a limitation.
- https://www.mdpi.com/2072-6643/13/11/3969 – This double-blind RCT examined the effects of Tribulus terrestris on 18 athletes participating in CrossFit training. The study found no significant benefits in body composition or performance. The authors acknowledged that the study was underpowered due to the small sample size (n<20/group).
- https://pubmed.ncbi.nlm.nih.gov/40219032/ – This study investigated the effects of Tribulus terrestris on sperm parameters. The results showed a 62.4% improvement in sperm concentration (SDM=0.624, p=0.013) and a 74.2% improvement in motility (SDM=0.742, p=0.001). These findings suggest a potential benefit for male fertility.
- https://osf.io/stavb/ – This study investigated the effects of Tribulus terrestris on sexual function. The results showed significant score improvements in FSD (5 RCTs, n=279). These findings suggest a potential benefit for female sexual dysfunction.