ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Valeriana 12C

Also known as: Valerian, Valerian root, Valeriana officinalis

Overview

Valerian (*Valeriana officinalis*) is a perennial plant native to Europe and Asia, widely recognized for its sedative properties. It has been traditionally used as a herbal supplement to promote relaxation and improve sleep quality. Valerian is available in various forms, including herbal teas, capsules, tinctures, and extracts. Its primary application is as a sleep aid, often used as an alternative to pharmaceutical sleep medications. While research on valerian's efficacy in treating insomnia is mixed, some studies suggest it can improve sleep quality and reduce sleep latency. The active compounds in valerian are believed to interact with the central nervous system, potentially affecting neurotransmitter activity and promoting a calming effect. The quality of available evidence varies, with some studies lacking rigorous methodology or consistency in results, highlighting the need for further research to fully understand its benefits and mechanisms of action.

Benefits

Valerian is primarily used to improve sleep quality and reduce sleep latency, although the evidence is somewhat inconsistent. Some studies suggest that valerian can be effective in improving sleep, particularly in individuals with mild insomnia. Elderly individuals with insomnia may experience improved sleep onset and maintenance. The clinical significance of valerian's effects is often debated due to the variability in study findings. Additionally, valerian may have anxiolytic effects, though the evidence supporting this benefit is limited. Benefits may be observed after several days to weeks of consistent use.

How it works

Valerian is believed to act on the central nervous system, potentially interacting with GABA receptors to promote relaxation and reduce anxiety. The exact mechanism of action is not fully understood, but it is thought that valerian compounds may influence sleep-wake cycles by affecting neurotransmitter activity. GABA receptors are a potential target, as valerian extracts have been shown to modulate GABAergic neurotransmission. The bioavailability of valerian compounds is not well understood and may vary depending on the preparation method.

Side effects

Valerian is generally considered safe when used appropriately, but it can cause side effects in some individuals. Common side effects include dizziness, stomach upset, and headache. Uncommon side effects may include allergic reactions, although these are rare. Valerian may interact with other sedatives, antidepressants, or alcohol, potentially increasing drowsiness or other adverse effects. It is contraindicated for use with alcohol or during pregnancy without medical supervision. Caution is advised in children and pregnant women due to limited safety data. It's important to discontinue use and consult a healthcare professional if any unusual or severe symptoms occur.

Dosage

The typical dosage of valerian root extract ranges from 500 mg to 2,000 mg per day. For sleep improvement, a common recommendation is 500 mg to 1,000 mg taken 30 minutes to 1 hour before bedtime. The optimal dosage may vary depending on the individual and the specific product. Capsules or teas are common forms of valerian supplementation. While a maximum safe dose is not well-established, it is generally considered safe up to 2,000 mg per day. Bioavailability may be influenced by the preparation method. It is advisable to start with a lower dose and gradually increase as needed, while monitoring for any adverse effects.

FAQs

Is valerian safe to use?

Valerian is generally safe for most adults when used as directed, but it can cause side effects like dizziness or stomach upset. Avoid combining it with alcohol or other sedatives.

How long does it take for valerian to work?

The effects of valerian may be noticeable after several days to weeks of consistent use. It is best taken 30 minutes to 1 hour before bedtime to aid sleep.

Can valerian cure insomnia?

Valerian is not a cure for insomnia but may help improve sleep quality and reduce sleep latency in some individuals. Results can vary, and it may not be effective for everyone.

Are there any drug interactions with valerian?

Yes, valerian may interact with sedatives, antidepressants, and alcohol, potentially increasing drowsiness. Consult a healthcare professional if you are taking other medications.

Can pregnant or breastfeeding women use valerian?

It is advised to avoid valerian during pregnancy and breastfeeding unless under medical supervision due to limited safety data in these populations.

Research Sources

  • https://pubmed.ncbi.nlm.nih.gov/10767649/ – This study investigates the effects of valerian root extract on sleep quality. While the specific details of the study would need to be extracted from the full text, PubMed provides a starting point for understanding the research on valerian's impact on sleep.
  • https://faculty.washington.edu/vitiello/Recent%20Publications/Taibi%20Valerian%20Review.pdf – This systematic review examines the evidence for valerian's efficacy in treating insomnia. The review analyzes multiple trials and highlights the inconsistent methodologies and results across studies, suggesting that the evidence for valerian's effectiveness is inconclusive.
  • https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1485693/epub – This research article explores the potential psychiatric benefits of valerian. The study investigates the effects of valerian on mental health conditions, providing insights into its possible role in psychiatric treatment.
  • https://www.hri-research.org/wp-content/uploads/2014/07/Homeopathy-Overview-Report.pdf – This overview report discusses the principles and practices of homeopathy, including the use of highly diluted substances like Valeriana 12C. It provides a general understanding of homeopathic treatments and their theoretical basis.
  • https://pubmed.ncbi.nlm.nih.gov/37899385/ – This randomized controlled trial assesses the impact of valerian extract on sleep quality and sleep latency in adults with sleep complaints. The study found that valerian extract improved sleep quality and reduced sleep latency in the participants, indicating a potential benefit for individuals with mild insomnia symptoms.

Supplements Containing Valeriana 12C

Moon Drops by Moon Drops
50

Moon Drops

Moon Drops

Score: 50/100