White Button Fruiting Body Extract
Also known as: White Button Mushroom, Button Mushroom, *Agaricus bisporus*
Overview
White Button Mushrooms (*Agaricus bisporus*) are globally recognized for their culinary use and potential health benefits. These mushrooms are rich in essential nutrients including carbohydrates, proteins, fibers, vitamins, and minerals. They are consumed both as a food ingredient and as a dietary supplement, thought to confer advantages such as immune system support and antioxidant effects attributed to their bioactive compounds, particularly beta-glucans. While there are promising findings in animal studies regarding their immunomodulatory effects, the research maturity level remains moderate with a notable requirement for comprehensive human trials to validate these benefits and understand their implications fully. Currently available evidence is variable, with some human studies suggesting potential health impacts, but rigorous research is still needed to establish concrete health outcomes and safety profiles.
Benefits
Studies have indicated that *Agaricus bisporus* may enhance immune functionality, particularly through the stimulation of natural killer (NK) cell activity observed in animal models. While human studies are limited, preliminary findings suggest these mushrooms could be beneficial for individuals looking to bolster immune function. Additionally, there are indications of potential antitumor and antiviral properties due to the immune modulation effects of the mushroom's bioactive components. However, specific effect sizes and the clinical significance of these benefits remain inadequately documented in human populations, and more focused research is essential to substantiate these claims.
How it works
The mechanisms of *Agaricus bisporus* primarily involve immune system modulation, likely through interactions with beta-glucans that enhance natural killer cell activity. These pathways suggest that the bioactive compounds in the mushrooms may stimulate immune responses, but precise molecular targets and the specific engagements with the body's biological systems are still not fully elucidated, particularly in human studies.
Side effects
Overall, *Agaricus bisporus* is regarded as safe when consumed as food, although safety data for supplements is less comprehensive. Commonly reported side effects are limited but may include gastrointestinal upset in some consumers. There have been no reports of rare or severe adverse effects. As specific drug interactions and contraindications for this mushroom extract are not well-studied, individuals, particularly pregnant or breastfeeding women, should consult healthcare providers prior to supplementation due to insufficient data on safety in these populations. It is important to approach the supplementation of this ingredient with caution, recognizing the current gaps in documented safety profiles.
Dosage
The minimum effective dose of *Agaricus bisporus* for supplementation has not been established, and optimal dosage ranges remain poorly defined in the available literature. There are currently no established upper limits or maximum safe doses, nor are there specific guidelines regarding the timing of administration. Common supplement forms include capsules or powders, but their absorption factors have not been extensively studied. Due to the lack of standardized dosing recommendations, prospective users are advised to consult healthcare professionals to determine potential dosages that align with personal health objectives.
FAQs
Is *Agaricus bisporus* safe to consume?
Generally considered safe as food, though safety as a supplement is less clear; consult a healthcare provider.
What are the expected health benefits?
Potential immune system support noted, but robust human evidence is lacking for definitive health benefits.
How should I take this supplement?
There are no specific guidelines for timing or administration; consult a healthcare provider for personalized advice.
Are there any side effects?
Generally safe, but may cause gastrointestinal upset in some individuals; no rare side effects reported.
What are common misconceptions about this mushroom?
Many overestimate health benefits, unaware of limited evidence from human studies.
Research Sources
- https://www.fda.gov/media/182240/download – This GRAS notice outlines that fiber extracted from *Agaricus bisporus* is recognized as safe for use as an antimicrobial ingredient, although it does not detail human health outcomes.
- https://pubmed.ncbi.nlm.nih.gov/17513409/ – A review paper discussing various nutritional and medical benefits of *Agaricus bisporus*, emphasizing its potential immune-modulating effects but highlighting the need for more human trials.
- https://www.researchgate.net/publication/320443791_The_nutritional_and_medical_benefits_of_Agaricus_Bisporus_A_review – This review compiles existing literature on the health benefits of *Agaricus bisporus*, noting its nutritional profile and possible medical applications while stressing the absence of robust human trial data.
- https://aquafishcrsp.oregonstate.edu/aquafish-nop – An overview without research conclusions, focusing on the aquatic aspect of *Agaricus bisporus*, more focused on practical applications rather than health benefits.
- https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2021.6516 – A report by EFSA discussing the safety assessment of food ingredients including those derived from *Agaricus bisporus*, reaffirming the general safety profile of the mushroom but lacking specific human health studies.
Supplements Containing White Button Fruiting Body Extract
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