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White Button Mushroom Fruit Extract

Also known as: White Button Mushroom, Button Mushroom, Agaricus bisporus

Overview

White Button Mushrooms (*Agaricus bisporus*) are one of the most commonly consumed edible mushrooms worldwide, valued for their culinary versatility and potential health benefits. They contain various bioactive compounds, including conjugated linoleic acid (CLA), which is studied for its potential anticancer properties. This mushroom is primarily used in dietary supplements aimed at boosting immune function and possibly preventing certain cancers. The current level of research regarding its efficacy is moderate, with promising preclinical findings suggesting potential health benefits, especially in cancer-related contexts. However, there remains a need for more rigorous clinical trials to substantiate these claims and confirm the safety and effectiveness of supplementation.

Benefits

Research suggests that White Button Mushroom extracts may inhibit the proliferation of cancer cells and promote apoptosis in cancer cell lines, particularly prostate cancer, based on studies conducted in vitro and in animal models. Additionally, while there is limited evidence regarding benefits for cognitive function and mood enhancements, some studies suggest that these mushrooms may provide health advantages when included in a balanced diet, such as the Mediterranean diet. The extraction of specific benefits for distinct populations—particularly men at risk for prostate cancer—is highlighted in preliminary research, prompting interest in further investigation while underscoring the need for more comprehensive human studies to validate these effects.

How it works

The potential mechanisms of action for White Button Mushroom extracts involve the modulation of myeloid-derived suppressor cells (MDSCs), which may enhance the immune response against tumors. The presence of conjugated linoleic acid (CLA) may influence cellular pathways associated with proliferation and apoptosis, suggesting a complex interaction with immune system dynamics and tumor growth processes. The specific absorption and bioavailability of components within the extract are not well documented, indicating an area requiring further study.

Side effects

White Button Mushroom supplements are generally regarded as safe when consumed in food quantities; however, the safety profile for supplemental forms is less established. Common side effects may include allergic reactions or gastrointestinal disturbances, though these are not well documented. Rare side effects are not specifically identified and may vary between individuals. Caution is advised when combining these supplements with immunosuppressive medications or in populations such as pregnant or breastfeeding women, where data are insufficient. Additionally, individuals who are immunocompromised may need to exercise caution when considering this supplement.

Dosage

No minimum effective dose for White Button Mushroom supplements has been established, and optimal dosage ranges vary across studies that explore specific extract concentrations. The maximum safe dose is currently undefined, and while no strict timing recommendations exist, it is advisable to consult healthcare professionals for guidance when using supplements. The presence of fresh mushrooms is generally considered safe, but users should approach supplement forms with care, keeping in mind individual absorption factors that are not well studied.

FAQs

Is it safe to take White Button Mushroom supplements?

These supplements are generally safe as food, but their safety in higher concentrations needs more research. Consult with a healthcare provider prior to use, especially for cancer prevention.

How do I include White Button Mushrooms in my diet for health benefits?

Incorporating fresh mushrooms into a balanced diet, such as a Mediterranean-style diet, may enhance overall health; supplements should be approached with professional advice.

What benefits can I expect from White Button Mushroom Fruit Extract?

Potential immune support and anticancer effects are suggested, but definitive human evidence is still lacking, making further research critical.

Can I take White Button Mushroom supplements with other medications?

Caution is advised as there may be interactions with immunosuppressive drugs. Always consult a healthcare provider for personalized advice.

Is the extract as good as using fresh mushrooms?

Fresh mushrooms are generally safe and nutritious, but the extraction concentrations may differ. Consult professionals for best practice.

Research Sources

https://www.mdpi.com/2304-8158/13/15/2319 – This study explores the nutritional and bioactive components of various mushrooms, particularly focusing on their potential health benefits, including anticancer properties.
https://www.news-medical.net/news/20241112/Study-uncovers-why-white-button-mushrooms-may-help-prevent-prostate-cancer-progression.aspx – Research highlights how White Button Mushrooms may influence immune responses in prostate cancer progression, emphasizing the need for continued investigations into this phenomenon.
https://www.fda.gov/media/182240/download – This FDA document outlines general safety assessments of mushrooms, including the White Button variety, covering potential health benefits and safety data.
https://pubmed.ncbi.nlm.nih.gov/19005974/ – This publication reports on the anticancer effects of mushrooms in vitro, indicating promising results that warrant further human clinical trials.
https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2021.6516 – This article reviews various food supplements, including mushrooms, discussing their safety, efficacy, and potential health implications.