Zynamite Mango Extract
Also known as: Zynamite, Mango Leaf Extract, Mangifera indica
Overview
Zynamite is a patented extract derived from the leaves of the mango tree (*Mangifera indica*), standardized to contain at least 60% mangiferin, a polyphenolic compound known for its health benefits. This extract is marketed as a natural alternative to caffeine, enhancing mental and physical performance without the adverse effects commonly associated with stimulant supplements. Since its introduction in 2018, Zynamite has been evaluated in several clinical trials, revealing promising results in cognitive tasks, physical performance, and sports recovery. Notably, it does not elevate heart rate or blood pressure, making it suitable for individuals sensitive to caffeine. Studies indicate its efficacy in improving cognitive accuracy for up to five hours and enhancing muscle performance and recovery in active populations.
Benefits
Zynamite has demonstrated several evidence-based benefits, particularly in cognitive and physical performance. A double-blind, placebo-controlled study indicated a significant improvement in cognitive tasks, particularly attention and memory, after a single 300 mg dose. In physical performance, a combination of Zynamite and quercetin led to improved repeated-sprint performance, yielding increases in peak power output of 2.8% to 3.8% compared to placebo. Additionally, it may help in recovery by reducing muscle damage and pain post-exercise. Research shows moderate effect sizes for these benefits, particularly favorable for athletes and physically active individuals, with significant effects observed within an hour of dosing for physical performance and lasting cognitive effects for at least five hours.
How it works
Zynamite primarily functions by inhibiting the catechol-O-methyltransferase (COMT) enzyme, thereby increasing levels of catecholamines like dopamine, which can enhance mood and focus. It enhances brain oxygenation, improves brain cell functioning, and promotes long-term potentiation in the hippocampus, which is crucial for learning and memory. In muscle tissues, Zynamite improves oxygen extraction and mitochondrial function during exercise, mimicking the biochemical effects of regular physical activity.
Side effects
Zynamite is reported to have a favorable safety profile, not significantly increasing heart rate or blood pressure, which is a major advantage over caffeine-based products. In the available literature, there are no common side effects documented; however, its interactions with CNS-active substances warrant caution. While there are no identified uncommon or rare side effects, it is essential to consider that safety in special populations, including pregnant or breastfeeding women, has not been extensively studied. Given the promising safety data, it is advisable for users to observe their response upon initiation.
Dosage
For cognitive enhancement, a single dose of 300 mg is recommended, while for physical performance benefits, a dosage of 140 mg in conjunction with quercetin has been effective. Zynamite can be taken as needed for cognitive benefits, while for optimal athletic performance, it should be consumed approximately one hour prior to exercise. The water-soluble form, known as Zynamite S, is suggested for better bioavailability, and no maximum safe dose has been established as the studied doses have been well-tolerated.
FAQs
Does Zynamite have any stimulatory effects?
No, Zynamite does not produce stimulatory effects like increased heart rate or blood pressure, making it a safe alternative to caffeine.
How should Zynamite be taken for performance benefits?
For cognitive benefits, it can be taken as needed. For physical performance, it's best to take Zynamite one hour before exercise.
What results can I expect from using Zynamite?
Users can expect improved cognitive performance, enhanced physical output, and faster recovery from strenuous activities.
Is Zynamite safe for everyone?
Zynamite is generally safe, but specific groups like pregnant women or those with certain medical conditions should consult a healthcare provider.
Research Sources
- https://nutraceuticalbusinessreview.com/a-natural-alternative-to-caffeine-without-the-side – This article discusses Zynamite as a natural alternative to caffeine, highlighting its safety profile and cognitive enhancement benefits.
- https://www.plthealth.com/product-catalog/zynamite – A product catalog entry detailing the features, uses, and benefits of Zynamite, including its standardized extract properties.
- https://www.mdpi.com/2072-6643/11/11/2592 – This study presents a double-blind, placebo-controlled trial showing the cognitive benefits of Zynamite, revealing significant improvements in attention and memory.
- https://www.scirp.org/journal/paperinformation?paperid=84662 – The article reviews the physical performance impacts of Zynamite, documenting enhanced sprint capabilities and muscle oxygen extraction in active individuals.
- https://www.semanticscholar.org/paper/A-Single-Dose-of-The-Mango-Leaf-Extract-Zynamite%C2%AE-Gelabert-Rebato-Martin%E2%80%90Rincon/71498111adf543963f599e39aef068e7a2f40d9f – A focused study on Mango Leaf Extract Zynamite which confirms its efficacy in improving cognitive performance in participants after a single dose.
