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B-12 Intrinsic Factor

B-12 Intrinsic Factor

Progressive Professional from Progressive Laboratories

#Vitamin B
70
Safety72
Efficacy68
Transparency62
Based on Examine, Wikipedia, and 23 other sources

Overview

This supplement is highly effective for its intended purpose: addressing Vitamin B12 deficiency caused by malabsorption, particularly for conditions like pernicious anemia. The inclusion of intrinsic factor, along with appropriate doses of B12 and folate, supports robust absorption and metabolic function. However, its effectiveness is specific to this target group and offers little added value for individuals with healthy B12 absorption.

The Good

Incorporates Intrinsic Factor, a key component for robust Vitamin B12 absorption in individuals with malabsorption disorders (e.g., pernicious anemia, gastric bypass).

Provides a substantial dose of Vitamin B12 (500 mcg), effective for addressing deficiencies.

Includes Folate (800 mcg as Quatrefolic, a trademarked, bioavailable form), which synergistically supports B12's role in methylation and red blood cell formation.

The Bad

Intrinsic Factor is animal-derived (porcine), making it unsuitable for vegetarians/vegans.

The product's efficacy is limited to individuals with B12 malabsorption; it offers no significant additional benefit for those with normal absorption.

Specific B12 form is not specified (e.g., cyanocobalamin vs. methylcobalamin), which can impact bioavailability for some individuals.

Is it for you?

Best For: Individuals with B12 deficiency, those seeking energy support, people with absorption issues

Skip If: You have a known allergy to any ingredients or are advised against B12 supplementation by a healthcare professional.

Ingredients Analysis

Folate

800 mcg

Vitamin B12

500 mcg

Biotin

300 mcg

Intrinsic Factor

20 mg

How to Use

Take as directed on product packaging, typically one capsule daily with a meal.

Frequency:

Daily

Best Time:

Morning

When:

With food

Who Should Use This

Best For:

Individuals with B12 deficiency, those seeking energy support, people with absorption issues

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