CA-AKG Calcium Alpha Ketoglutarate
DONOTAGE.ORG
Overview
This product contains Calcium Alpha Ketoglutarate (CA-AKG), an ingredient with emerging research in anti-aging, muscle, and bone health. However, the serving size of 400 mg is significantly lower than doses that have shown clinical benefits in human or animal studies, making the overall effectiveness of this specific product for its implied benefits highly questionable.
The Good
Generally Safe: Calcium Alpha Ketoglutarate (AKG) has a good safety profile and is generally well-tolerated, especially at the provided low dosage.
Potential for Longevity Research: AKG is a molecule of interest in longevity and anti-aging research, though much of the compelling evidence comes from animal studies at higher doses.
Easy to Incorporate: As a single capsule, it is convenient to add to a daily supplement regimen.
The Bad
Low Dose: The per-serving dose of 400 mg Calcium Alpha Ketoglutarate is significantly lower than optimal dosages used in human studies (e.g., 6 grams/day for bone health, or 2% Ca-AKG in diet for lifespan effects in animals). This makes significant benefits at this dose unlikely.
Limited Human Research: While promising, robust human clinical trials for AKG, especially at supplement-relevant doses, are still emerging, with much of the compelling data coming from animal models.
Lack of Established Optimal Dosage: The exact optimal human dosage for various benefits (anti-aging, muscle, bone health) is not yet clearly defined, with studies showing benefits at much higher ranges than provided here.
Is it for you?
Best For: Individuals interested in longevity, metabolic support, cellular health
Skip If: You are pregnant or nursing, or have pre-existing medical conditions without consulting a doctor.
Ingredients Analysis
How to Use
Typically taken orally with water, dosage as per product label instructions.
Daily
Morning or Evening
With food
