ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Goldenseal 480 mg

Goldenseal 480 mg

Douglas Laboratories

#Other
73
Safety70
Efficacy75
Transparency80
Based on Examine, Wikipedia, and 23 other sources

Overview

Goldenseal has a moderate level of research maturity, with some promising in-vitro and clinical data supporting its antimicrobial and digestive benefits. The 480 mg dose is within ranges traditionally used, but specific minimum effective doses are not well-established, and optimal dosage can vary. While its primary active compound, berberine, is recognized for its effects, more rigorous clinical trials on Goldenseal itself are needed to confirm precise efficacy and optimal dosing for various conditions.

The Good

Utilizes a traditional herbal remedy with historical use.

Contains Goldenseal, which has recognized antimicrobial properties, particularly due to berberine.

May support digestive health and immune function.

The Bad

Lack of robust long-term safety data for Goldenseal.

Significant potential for drug interactions, requiring professional consultation.

Contraindicated for vulnerable populations (pregnant/breastfeeding women, infants).

Is it for you?

Best For: Individuals seeking natural immune support, those interested in traditional herbal remedies, digestive health support

Skip If: Pregnant, breastfeeding, have liver disease, or taking certain medications (e.g., blood thinners, immunosuppressants)

Ingredients Analysis

Goldenseal Powder

480 mg

How to Use

Take 1 capsule daily, or as directed by a healthcare professional.

Frequency:

Daily

Best Time:

Morning or Evening

When:

With food

Who Should Use This

Best For:

Individuals seeking natural immune support, those interested in traditional herbal remedies, digestive health support

Similar Products

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement by Vetriscience®

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement

Vetriscience®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT by GNARLY®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT

GNARLY®

Muscle memory Creatine Powder supplement by Ora®

Muscle memory Creatine Powder supplement

Ora®

Amazing Formulas MSM (Methylsulfonylmethane) Supplement by Amazing Nutrition

Amazing Formulas MSM (Methylsulfonylmethane) Supplement

Amazing Nutrition

Fiber GDX Dietary Supplement Fiber / Orange Flavor by THE PAUSENUTRITION®

Fiber GDX Dietary Supplement Fiber / Orange Flavor

THE PAUSENUTRITION®

PROSTATE HEALTH SUPPLEMENT by OFFSTATE

PROSTATE HEALTH SUPPLEMENT

OFFSTATE

Recommended Articles

Optimal Berberine Dosing Guide

Optimal Berberine Dosing Guide

Optimal berberine intake involves 500-1500 mg/day, split 2-3 times, ideally 30-60 minutes before meals, tailored to individual needs.

Cycling Berberine: Avoid Tolerance, Maximize Benefits

Cycling Berberine: Avoid Tolerance, Maximize Benefits

Cycling berberine can help prevent tolerance and enhance its metabolic and cardiovascular benefits.

Berberine vs. Metformin: Glucose Control Efficacy

Berberine vs. Metformin: Glucose Control Efficacy

Clinical trials show berberine can effectively control glucose levels, comparable to metformin, with a different side effect profile.

Berberine vs Metformin: Weight Loss Showdown 2025

Berberine vs Metformin: Weight Loss Showdown 2025

Berberine and metformin both show promising weight loss effects by activating AMPK, with berberine possibly having a slight edge in certain populations.