ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Goldenseal

Goldenseal

Solgar

#Other
60
Safety70
Efficacy50
Transparency80
Based on Examine, Wikipedia, and 23 other sources

Overview

This goldenseal supplement contains a moderate dose of raw goldenseal powder, which has several health benefits due to its berberine content. While berberine shows promise in metabolic health and antimicrobial effects, most research is in-vitro. The limited nature of direct clinical studies on goldenseal itself requires caution.

The Good

May provide mild antimicrobial support

Contains berberine, which has potential metabolic benefits

May provide some anti-inflammatory support

The Bad

Potential for gastrointestinal discomfort with higher doses

May interact with certain medications (e.g., metformin, midazolam)

Not advisable for pregnant women due to risk of uterine stimulation

Is it for you?

Best For: Individuals seeking traditional immune support, those looking to support mucous membrane health

Skip If: Pregnant, breastfeeding, have liver disease, or taking certain medications (e.g., blood thinners, immunosuppressants)

Ingredients Analysis

Total Carbohydrates

Iron

0.4 mg

Raw Goldenseal Powder

520 mg

How to Use

Typically, take one capsule one to three times daily, preferably with meals, or as directed by a healthcare practitioner.

Frequency:

Daily (short-term)

Best Time:

Anytime

When:

With food

Who Should Use This

Best For:

Individuals seeking traditional immune support, those looking to support mucous membrane health

Similar Products

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement by Vetriscience®

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement

Vetriscience®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT by GNARLY®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT

GNARLY®

Muscle memory Creatine Powder supplement by Ora®

Muscle memory Creatine Powder supplement

Ora®

Amazing Formulas MSM (Methylsulfonylmethane) Supplement by Amazing Nutrition

Amazing Formulas MSM (Methylsulfonylmethane) Supplement

Amazing Nutrition

Fiber GDX Dietary Supplement Fiber / Orange Flavor by THE PAUSENUTRITION®

Fiber GDX Dietary Supplement Fiber / Orange Flavor

THE PAUSENUTRITION®

PROSTATE HEALTH SUPPLEMENT by OFFSTATE

PROSTATE HEALTH SUPPLEMENT

OFFSTATE

Recommended Articles

Optimal Berberine Dosing Guide

Optimal Berberine Dosing Guide

Optimal berberine intake involves 500-1500 mg/day, split 2-3 times, ideally 30-60 minutes before meals, tailored to individual needs.

Cycling Berberine: Avoid Tolerance, Maximize Benefits

Cycling Berberine: Avoid Tolerance, Maximize Benefits

Cycling berberine can help prevent tolerance and enhance its metabolic and cardiovascular benefits.

Berberine vs. Metformin: Glucose Control Efficacy

Berberine vs. Metformin: Glucose Control Efficacy

Clinical trials show berberine can effectively control glucose levels, comparable to metformin, with a different side effect profile.

Berberine vs Metformin: Weight Loss Showdown 2025

Berberine vs Metformin: Weight Loss Showdown 2025

Berberine and metformin both show promising weight loss effects by activating AMPK, with berberine possibly having a slight edge in certain populations.