ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2026 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Methylene Blue Solution USP 1%

Methylene Blue Solution USP 1%

AZ LABORATORY

#Other
55
Safety70
Efficacy40
Transparency75
Based on Examine, Wikipedia, and 23 other sources

Overview

This product contains Methylene Blue, which has shown promise in treating specific medical conditions like septic shock, primarily through intravenous administration. However, the efficacy of low-dose oral Methylene Blue for improving brain performance in healthy individuals is not well-established. The current evidence is preliminary, and more research is needed to support the marketed nootropic claims. The benefits observed in clinical settings may not directly translate to healthy individuals using this supplement.

The Good

Potential Neuroprotective Effects: Some research suggests Methylene Blue may have neuroprotective properties.

May Improve Blood Pressure in Specific Clinical Contexts: Studies indicate Methylene Blue can increase mean arterial pressure in septic shock patients.

Simple Administration: Easy to administer by adding drops to water or juice.

The Bad

Potential Drug Interactions: Methylene Blue may interact with serotonergic drugs, increasing the risk of serotonin syndrome.

Side Effects: Can cause blue discoloration of urine, nausea, and headache.

Contraindications: Contraindicated in individuals with known hypersensitivity to Methylene Blue and those with G6PD deficiency.

Is it for you?

Best For: Individuals seeking cognitive support, mitochondrial health, or antioxidant benefits.

Skip If: Pregnant, nursing, have G6PD deficiency, or are taking SSRIs/MAOIs.

Ingredients Analysis

Methylene Blue trihydrate, USP Grade

1 mg

How to Use

Typically taken orally as drops; dosage varies based on individual needs and concentration.

Frequency:

Daily

Best Time:

Morning

When:

With or without food

Who Should Use This

Best For:

Individuals seeking cognitive support, mitochondrial health, or antioxidant benefits.

Recommended Articles

Methylfolate & MTHFR: Dosage, Benefits, Side Effects

Methylfolate & MTHFR: Dosage, Benefits, Side Effects

Methylfolate supplementation can be beneficial for individuals with MTHFR variants, offering a personalized approach to enhancing folate metabolism.

Buy Pharmaceutical-Grade Methylfolate for MTHFR

Buy Pharmaceutical-Grade Methylfolate for MTHFR

Pharmaceutical-grade methylfolate is crucial for individuals with MTHFR mutations, offering higher bioavailability and supporting folate metabolism.

MTHFR Variants & B-Vitamin Absorption

MTHFR Variants & B-Vitamin Absorption

MTHFR variants alter B-vitamin processing, necessitating specific supplement forms for optimal health.

B Vitamins for MTHFR Mutation: Dosage & Types

B Vitamins for MTHFR Mutation: Dosage & Types

Individuals with MTHFR mutations need specific B vitamin forms and dosages, like methylfolate and methylcobalamin, for improved metabolism.