ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2026 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ

No image available

Silyplus 360 mg

SuperSmart

#Other
83
Safety85
Efficacy80
Transparency75
Based on Examine, Wikipedia, and 23 other sources

Overview

Silyplus 360 mg utilizes Siliphos, a highly bioavailable form of milk thistle extract. Clinical research supports the efficacy of silybin phospholipid complexes in improving liver health parameters, notably liver enzymes and steatosis, making this product a good option for liver support.

The Good

Enhanced Bioavailability: Utilizes Siliphos, a silybin-phosphatidylcholine complex, significantly improving the absorption of the active compound compared to standard milk thistle.

Liver Protection: Supports liver health through potent antioxidant, anti-inflammatory, and antifibrotic actions.

Research-Backed Dosing: The 360 mg daily dose aligns with typical effective dosages seen in clinical trials for silybin phospholipid complexes.

The Bad

Potential Drug Interactions: May interact with certain medications metabolized by CYP450 enzymes, though typically of low clinical significance.

Allergy Concerns: Contains soya lecithin and is derived from milk thistle, posing a risk for individuals with soy or milk thistle allergies.

Limited Direct RCTs on Siliphos Alone: While silymarin research is extensive, more direct, large-scale RCTs specifically on Siliphos for all claimed benefits are still needed.

Is it for you?

Best For: Individuals seeking liver support, those exposed to environmental toxins, general wellness

Skip If: You are pregnant, breastfeeding, have a ragweed allergy, or are on medications that interact with milk thistle.

Ingredients Analysis

Siliphos

360 mg

How to Use

Typically, take one capsule daily with a meal, or as directed by a healthcare professional.

Frequency:

Daily

Best Time:

Morning or Evening

When:

With food

Who Should Use This

Best For:

Individuals seeking liver support, those exposed to environmental toxins, general wellness