Spermidine, Rice Germ Extract, 1 mg

California Gold Nutrition

#Other

Safety90

Efficacy55

Transparency85

Based on Examine, Wikipedia, and 23 other sources

Overview

The supplement provides 1 mg of spermidine from rice germ extract. While spermidine is a promising compound for cellular health and longevity, the 1 mg dose is at the lower end of the spectrum compared to doses used in studies showing cognitive or anti-aging benefits (which often range from 5-10 mg or higher). Therefore, the overall effectiveness for significant physiological changes at this specific dose is currently not well-supported by robust clinical data.

The Good

Natural Source of Spermidine: Sourced from rice germ extract, a natural and food-derived form of spermidine, which is often preferred by consumers.

Supports Cellular Autophagy: Spermidine is known to induce autophagy, a cellular clean-up process crucial for maintaining cellular health and potentially slowing aging.

Potential Longevity Benefits: Emerging research suggests spermidine may play a role in promoting longevity and healthy aging through its influence on cellular processes.

The Bad

Suboptimal Spermidine Dose: The 1 mg dose of spermidine is considerably lower than the 5-10 mg doses shown to be effective in some human studies for certain benefits like cognitive function.

Limited Direct Evidence for 1mg Dose: While spermidine shows promise, direct clinical evidence for significant health benefits at a 1 mg supplemental dose is limited and not as robust as for higher doses.

Rice Germ Extract Dosage Not Directly Linked to Spermidine Content: The product states 100 mg of Rice Germ Extract, which yields 1 mg of spermidine. However, typical effective doses of rice germ extract for metabolic benefits are much higher (e.g., 25g twice daily for obesity management), making the 100 mg extract dose likely insufficient for those broader effects.