ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
St. John's Wort 450

St. John's Wort 450

Source Naturals

#Other
55
Safety45
Efficacy65
Transparency80
Based on Examine, Wikipedia, and 23 other sources

Overview

This St. John's Wort supplement is designed to support a positive mental outlook, primarily for mild to moderate depression. The product is standardized to 0.3% hypericins, ensuring a consistent 1.35mg of hypericins per tablet, 2.7mg daily, which aligns with clinical research on efficacious dosages for mood enhancement and depression treatment. Consistent, long-term usage of up to six weeks is needed for full effects to be realized.

The Good

May improve mood and mental outlook

Standardized extract ensures consistent dosage

Vegetarian-friendly formula with no common allergens

The Bad

Significant Drug Interactions

Potential Photosensitivity

Gastrointestinal Discomfort

Is it for you?

Best For: Individuals seeking mood support, those experiencing mild to moderate depressive symptoms

Skip If: You are taking prescription medications (especially antidepressants, birth control, blood thinners), are pregnant or breastfeeding, or have bipolar disorder.

Ingredients Analysis

St. John'S Wort

450 mg

Hypericins

1.35 mg

How to Use

Typically taken as one capsule, one to two times daily, with meals.

Frequency:

Daily

Best Time:

Morning & Evening

When:

With food

Who Should Use This

Best For:

Individuals seeking mood support, those experiencing mild to moderate depressive symptoms

Similar Products

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement by Vetriscience®

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement

Vetriscience®

St. John's Wort by Christopher's Original Formulas

St. John's Wort

Christopher's Original Formulas

St. John's Wort by Herb Pharm

St. John's Wort

Herb Pharm

St. John's Wort by Wonder Laboratories

St. John's Wort

Wonder Laboratories

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT by GNARLY®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT

GNARLY®

Muscle memory Creatine Powder supplement by Ora®

Muscle memory Creatine Powder supplement

Ora®

Recommended Articles

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal supplements may interact with COVID-19 antivirals, requiring careful consideration and further research.

How Mood Support Supplements Affect Neurotransmitters

How Mood Support Supplements Affect Neurotransmitters

Mood support supplements contain ingredients that can influence neurotransmitter levels, improving mood and cognitive function.

Boosting Health: Synergistic Ingredient Pairs

Boosting Health: Synergistic Ingredient Pairs

Combining certain ingredients, like curcumin and piperine, can significantly enhance their health benefits through synergy.

Avoid These Ingredients Before Surgery

Avoid These Ingredients Before Surgery

Certain ingredients, especially supplements that affect blood clotting, should be avoided before surgery to prevent complications.