ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors
  • Partners

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2026 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
ST JOHN'S WORT

ST JOHN'S WORT

toniiq

#Other
63
Safety55
Efficacy70
Transparency80
Based on Examine, Wikipedia, and 23 other sources

Overview

This St. John's Wort supplement provides a standardized extract of Hypericum perforatum, aiming to support mood and alleviate symptoms of mild to moderate depression. The effectiveness relies on consistent daily use and may vary among individuals. It is crucial to consider potential interactions with medications and consult with a healthcare professional.

The Good

May help improve mood and reduce symptoms of mild to moderate depression.

Standardized extract for consistent potency.

Vegetarian capsules.

The Bad

May interact with certain medications.

Potential side effects like gastrointestinal issues, headache, and photosensitivity.

Not recommended for pregnant or nursing individuals.

Is it for you?

Best For: Individuals seeking natural mood support, those experiencing mild to moderate depressive symptoms (under medical supervision)

Skip If: You are taking prescription medications (especially antidepressants, birth control, blood thinners), are pregnant or breastfeeding, or have bipolar disorder.

Ingredients Analysis

St John's Wort

1000 mg

Hypericum perforatum (aerial parts) 7:1 extract

0 mg

Std. to 0.3% Hypericins as St. John's Wort powder

1000 mg

Equivalent to 7,000 mg St. John's Wort powder

3 mg

How to Use

Typically, take 1-2 capsules daily with food, or as directed by a healthcare professional.

Frequency:

Daily

Best Time:

Morning or Evening

When:

With food

Who Should Use This

Best For:

Individuals seeking natural mood support, those experiencing mild to moderate depressive symptoms (under medical supervision)

Recommended Articles

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal supplements may interact with COVID-19 antivirals, requiring careful consideration and further research.

How Mood Support Supplements Affect Neurotransmitters

How Mood Support Supplements Affect Neurotransmitters

Mood support supplements contain ingredients that can influence neurotransmitter levels, improving mood and cognitive function.

Boosting Health: Synergistic Ingredient Pairs

Boosting Health: Synergistic Ingredient Pairs

Combining certain ingredients, like curcumin and piperine, can significantly enhance their health benefits through synergy.

Avoid These Ingredients Before Surgery

Avoid These Ingredients Before Surgery

Certain ingredients, especially supplements that affect blood clotting, should be avoided before surgery to prevent complications.