ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2026 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
USP GRADE METHYLENE BLUE

USP GRADE METHYLENE BLUE

BLUESUN

#Other
50
Safety60
Efficacy40
Transparency70
Based on Examine, Wikipedia, and 23 other sources

Overview

While Methylene Blue has demonstrated effectiveness in treating specific medical conditions such as sepsis and septic shock, its utility as a general dietary supplement is uncertain. Clinical applications show benefits in reducing vasopressor dependence and improving ICU outcomes in critically ill patients. However, its routine use for healthy individuals lacks sufficient evidence.

The Good

Potential Cognitive Benefits: Methylene Blue has been researched for its potential nootropic effects related to mitochondrial function and cerebral blood flow.

Antimicrobial Properties: Methylene Blue has known antimicrobial effects

USP Grade Quality: The product uses USP grade Methylene Blue, ensuring a certain level of quality and purity.

The Bad

Potential Drug Interactions: May interact with serotonergic drugs and other medications, which could lead to adverse effects.

Risk of Methemoglobinemia: Although rare, Methylene Blue can cause methemoglobinemia, a condition where hemoglobin cannot effectively carry oxygen.

Not evaluated by the FDA: The statements regarding this product's effects have not been evaluated by the Food and Drug Administration.

Is it for you?

Best For: Individuals interested in cognitive support, mitochondrial health, or biohacking, under professional guidance.

Skip If: You have G6PD deficiency, are pregnant or breastfeeding, or are taking SSRIs/SNRIs.

Ingredients Analysis

Methylene Blue (USP)

10 mg

How to Use

Typically taken orally, dosage varies based on desired effect and individual tolerance. Start with a low dose and consult a healthcare professional.

Frequency:

Daily

Best Time:

Morning

When:

With or without food

Who Should Use This

Best For:

Individuals interested in cognitive support, mitochondrial health, or biohacking, under professional guidance.

Recommended Articles

Methylfolate & MTHFR: Dosage, Benefits, Side Effects

Methylfolate & MTHFR: Dosage, Benefits, Side Effects

Methylfolate supplementation can be beneficial for individuals with MTHFR variants, offering a personalized approach to enhancing folate metabolism.

Buy Pharmaceutical-Grade Methylfolate for MTHFR

Buy Pharmaceutical-Grade Methylfolate for MTHFR

Pharmaceutical-grade methylfolate is crucial for individuals with MTHFR mutations, offering higher bioavailability and supporting folate metabolism.

MTHFR Variants & B-Vitamin Absorption

MTHFR Variants & B-Vitamin Absorption

MTHFR variants alter B-vitamin processing, necessitating specific supplement forms for optimal health.

B Vitamins for MTHFR Mutation: Dosage & Types

B Vitamins for MTHFR Mutation: Dosage & Types

Individuals with MTHFR mutations need specific B vitamin forms and dosages, like methylfolate and methylcobalamin, for improved metabolism.