Get Your Personalized Supplement StackSupplement Stack Quiz

Bellis perennis

Also known as: Bellis perennis, Daisy, Lawn Daisy

Overview

*Bellis perennis*, commonly known as the daisy, is a plant with a history of use in traditional medicine. It is primarily recognized for its potential health benefits, including antioxidant, antimicrobial, and anti-inflammatory effects. Key applications involve wound healing, anxiety reduction, and potential blood glucose management. Research indicates promising effects, but more rigorous clinical trials are needed to fully understand its efficacy and safety. *Bellis perennis* contains various bioactive compounds that contribute to its therapeutic properties. It is available in various forms, including teas, extracts, and topical applications. The plant is native to Europe and the Mediterranean region and is now found worldwide. Its historical use and preliminary research suggest potential benefits, but further studies are essential to validate these claims and establish safe usage guidelines. It is important to consult healthcare professionals before using *Bellis perennis* as a supplement, especially for individuals with pre-existing conditions or those taking medications.

Benefits

*Bellis perennis* exhibits several potential health benefits supported by preliminary research. It possesses antioxidant and antimicrobial properties, which may contribute to overall health and wellness. Studies suggest that *B. perennis* extracts may have anxiolytic effects, potentially acting through the GABAergic system, offering a natural alternative for anxiety management. Additionally, extracts from *B. perennis* have shown potential insulin mimetic properties, reducing blood glucose levels in experimental settings. Traditionally, it has been used for wound healing and may have anti-inflammatory properties, although more extensive research is needed to confirm these effects. The anxiolytic effects may be more pronounced in juveniles, while the effects in the elevated plus maze were more significant in adults, indicating age-specific benefits. While these findings are promising, further clinical trials are necessary to validate these benefits in humans and determine optimal dosages and safety profiles.

How it works

The anxiolytic effects of *Bellis perennis* may involve modulation of the GABAergic system, similar to benzodiazepines, which are known to reduce anxiety by enhancing GABA activity in the brain. The insulin mimetic properties could be related to the induction of GLUT4 translocation, a protein responsible for transporting glucose into cells, thereby reducing blood glucose levels. *Bellis perennis* interacts with the nervous system through its anxiolytic effects and with the metabolic system through its insulin mimetic properties. The GABAergic system is a known target for its anxiolytic effects, while the insulin signaling pathway is involved in its potential blood glucose-lowering effects. These mechanisms suggest that *Bellis perennis* may offer therapeutic benefits by influencing key biological pathways.

Side effects

While *Bellis perennis* is generally considered safe, comprehensive safety data are limited. Common side effects are not well-documented in the literature. Uncommon and rare side effects are also not specifically reported. Potential drug interactions may occur with sedatives due to its anxiolytic effects and with diabetes medications due to its insulin mimetic properties. Caution is advised in individuals with diabetes or those taking sedatives. Pregnant or breastfeeding women should consult healthcare providers before use due to the lack of extensive safety data in these populations. It is essential to monitor for any adverse reactions when using *Bellis perennis*, and individuals with known allergies to plants in the Asteraceae family should exercise caution. Further research is needed to fully characterize the safety profile of *Bellis perennis* and identify potential risks.

Dosage

The minimum effective dose of *Bellis perennis* is not well-established. Animal studies used doses of 20 to 60 mg/kg for anxiolytic effects, but these dosages may not be directly applicable to humans. The maximum safe dose is not clearly defined. There are no specific timing recommendations available for its use. *Bellis perennis* is typically used as aqueous extracts, but bioavailability and absorption data are limited. No specific required cofactors have been identified. Due to the limited research on optimal dosages and safety, it is crucial to consult with a healthcare provider before using *Bellis perennis* as a supplement. Further studies are needed to determine appropriate dosage ranges for different purposes and to establish safety thresholds.

FAQs

How is *Bellis perennis* traditionally used?

*Bellis perennis* is traditionally used in teas or as a topical application. However, its efficacy and safety as a supplement require further research before it can be widely recommended.

Are there any safety concerns with using *Bellis perennis*?

While generally considered safe, potential interactions with medications should be considered. Consult a healthcare provider if you are taking sedatives or diabetes medications before using *Bellis perennis*.

When is the best time to take *Bellis perennis*?

No specific timing is recommended, but it may be used as needed for anxiety or as part of a daily regimen for other benefits. Consult with a healthcare provider for personalized advice.

What results can I expect from using *Bellis perennis*?

Benefits may include reduced anxiety and improved blood glucose control, but these effects are based on limited studies. Individual results may vary, and it is not a substitute for medical treatment.

Is *Bellis perennis* a substitute for medical treatment?

No, it is not a substitute for medical treatment without consulting a healthcare provider. Always seek professional medical advice for any health concerns.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC10707873/ – This animal study investigated the antidepressive and anxiolytic effects of *Bellis perennis* extract in adult and juvenile Wistar albino rats. The findings indicated that high doses of the extract exhibited anxiolytic effects, suggesting potential benefits for anxiety management. However, the study is limited to animal models and lacks human trials, necessitating further research to validate these effects in humans.
https://journals.lww.com/prsgo/fulltext/2019/08001/arnica_montana_and_bellis_perennis_for_seroma.35.aspx – This clinical study examined the effects of *Bellis perennis* and *Arnica montana* on seroma formation in patients undergoing mastectomy and reconstruction. The results showed that the combination of these substances reduced seroma formation and opioid intake postoperatively. While the study suggests potential benefits in postoperative care, the specific effects of *Bellis perennis* alone are not isolated, requiring more specific studies to determine its individual contribution.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6222741/ – This study explored the insulin mimetic properties of *Bellis perennis* extracts through in vitro and in vivo experiments using fertilized eggs. The findings revealed that the extracts reduced blood glucose levels, indicating potential insulin mimetic effects. The study offers promising insights into the potential of *Bellis perennis* to influence glucose metabolism, but it was not conducted in humans, necessitating further research to confirm these effects in clinical settings.
https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.680930/full – This article discusses the use of complementary and alternative medicine in surgical settings, including the potential benefits of *Bellis perennis* for wound healing and pain management. It highlights the importance of integrating evidence-based practices to improve patient outcomes. The review suggests that *Bellis perennis* may have a role in postoperative care, but further research is needed to validate its specific effects and safety.
https://ebm.bmj.com/content/27/6/345 – This article provides an overview of evidence-based medicine and its application in clinical practice. It emphasizes the importance of using high-quality research to inform healthcare decisions. The article underscores the need for rigorous clinical trials to validate the efficacy and safety of herbal supplements like *Bellis perennis* before widespread use.