Boerhavia Diffusa
Also known as: Punarnava, Spreading Hogweed, *Boerhavia diffusa*
Overview
*Boerhavia diffusa* is a perennial herb native to tropical climates, particularly valued in traditional Ayurvedic medicine for its wide-ranging pharmacological potential. This herb is known for being rich in bioactive compounds, including flavonoids, alkaloids, and rotenoids, making it an important component in various herbal formulations. Traditionally used for its anti-inflammatory, antimicrobial, and antioxidant properties, it is often referred to as a 'Rasayana,' denoting its supposed rejuvenating qualities. Despite its historical uses, the body of research regarding *Boerhavia diffusa* is still moderate. Most available studies are based on in vitro or animal research, with few human trials confirming its efficacy, indicating the need for more rigorous and comprehensive studies to fully elucidate its health benefits and therapeutic scope.
Benefits
Research indicates that *Boerhavia diffusa* may possess anti-inflammatory and antioxidant effects, particularly seen in animal models. Limited data suggests it can reduce markers of inflammation and enhance antioxidant status. Its antimicrobial, anticancer, and anti-diabetic properties have been documented, mostly through in vitro and animal studies. However, quantifying these benefits in human populations remains challenging, with no well-established clinical trials demonstrating significant positive outcomes. Individuals seeking natural ways to support inflammation or oxidative stress may find potential in this supplement, although evidence of effect sizes and clinical significance is not well-documented in human studies.
How it works
*Boerhavia diffusa* likely acts through various biological pathways, primarily by modulating antioxidant and anti-inflammatory responses. Its bioactive compounds might influence immune system functionality and metabolic processes, though specific molecular targets and mechanisms remain poorly defined. Further research is required to clarify how these interactions translate to observable health benefits in humans.
Side effects
Overall, *Boerhavia diffusa* appears to have a favorable safety profile, but its human side effects are not well-documented due to limited studies. There are no reported common (>5%), uncommon (1-5%), or rare (<1%) side effects within the available literature. However, potential drug interactions have not been thoroughly studied, and caution is advised for pregnant or breastfeeding women due to the lack of data surrounding safety in these populations. Given the sparse safety information, individuals should consult healthcare professionals prior to using this supplement, especially when it comes to co-prescribed medications.
Dosage
Dosage guidelines for *Boerhavia diffusa* are not well-defined, as traditional uses vary widely and there are no established minimum effective or maximum safe doses. In its typical applications within traditional medicine, it is consumed as a tea or in extract form. As no standardized dosing exists, recommendations often rely on individual practitioner advice. Timing and absorption factors have not been extensively researched, and hence, further studies are needed to establish dosing protocols and effective timelines.
FAQs
Is *Boerhavia diffusa* safe to use?
While considered generally safe, comprehensive human studies are lacking; consult a healthcare provider before usage, particularly with other medications.
What benefits should I expect?
Potential benefits include antioxidant and anti-inflammatory effects, although clinical significance in humans is not well-documented.
When should I take *Boerhavia diffusa*?
There is no standardized timing recommended; consult with a health professional for personalized advice.
Can I use *Boerhavia diffusa* with other supplements?
Due to unknown interactions, it's best to seek advice from a healthcare provider before combining with other supplements.
Is there research supporting its efficacy?
Most research is based on animal and in vitro studies; more human trials are needed to confirm effects and efficacy.
Research Sources
- https://scirp.org/journal/paperinformation?paperid=111937 – This review highlights the ethnomedicinal significance of *Boerhavia diffusa*, noting its anti-inflammatory and antioxidant properties while emphasizing the lack of human clinical trial data.
- https://pubmed.ncbi.nlm.nih.gov/38033469/ – This study utilizes LC-MS/HRMS for metabolite profiling, discovering new phytochemicals in *Boerhavia diffusa* with potential anticancer properties, though primarily based on in vitro evidence.
- https://www.mdpi.com/2076-3921/10/12/2003 – This animal study presents preliminary findings on the anti-obesity effects of *Boerhavia diffusa*, suggesting it may influence cannabinoid receptor activity, yet the results are not directly applicable to humans.
- https://pubmed.ncbi.nlm.nih.gov/24949473/ – The review provides a comprehensive snapshot of *Boerhavia diffusa*'s diverse pharmacological benefits but calls for more focused clinical trials to substantiate claims.
- https://www.mdpi.com/2223-7747/11/9/1158 – This paper discusses various applications of *Boerhavia diffusa*, outlining its therapeutic properties but highlighting the necessity of further investigation into its human effects.
Supplements Containing Boerhavia Diffusa

Adaptocrine (K-2)
Apex Energetics

Carditone
Ayush Herbs

Liver Kidney
Organic India

Gouch!
Redd Remedies

Gouch!
Redd Remedies

Total Body Cleanse
Banyan Botanicals

Priority Lipo
Priority One Nutritional Supplements