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Epicor

Also known as: EpiCor, Epicor, Saccharomyces cerevisiae fermentate

Overview

EpiCor is a fermented product derived from Saccharomyces cerevisiae, commonly referred to as baker's yeast. It is produced from naturally occurring yeast and is recognized for its benefits to immune and gut health. EpiCor is rich in essential components like mannan-oligosaccharides (MOS), beta-glucans, and various bioactive compounds that foster healthy gut microbiota and enhance immune function. Numerous high-quality clinical studies have supported its efficacy, particularly for promoting immune health and digestive wellness. The overall research maturity level of EpiCor is categorized as moderate, indicating promising potential but necessitating further research.

Benefits

EpiCor has several evidence-based benefits, prominently a notable 40% reduction in upper respiratory tract infections (URTIs) among healthy adults as evidenced by a 28-week, double-blind, placebo-controlled study. It also supports gut health by enhancing beneficial gut bacteria and promoting the production of short-chain fatty acids, particularly butyrate, which is crucial for intestinal health. Additionally, EpiCor exhibits anti-inflammatory effects that help modulate cytokine levels. Most studies thus far have concentrated on healthy adults; however, there is potential for similar benefits in children based on findings from analogous yeast-derived products like Wellmune.

How it works

EpiCor promotes gut health by increasing beneficial bacteria and producing short-chain fatty acids, particularly butyrate. Its bioactive components, such as MOS and beta-glucans, interact with the gastrointestinal and immune systems to strengthen immune responses and support a healthy gut microbiome. These compounds specifically target gut-associated lymphoid tissue (GALT) and influence cytokine production, contributing to enhanced immune function.

Side effects

EpiCor is generally considered safe, with minimal side effects reported. No significant adverse effects occurring in more than 5% of users have been documented. Mild gastrointestinal symptoms, such as bloating or gas, may affect about 1-5% of individuals. Rare side effects (less than 1%) are not statistically significant. Although significant drug interactions are not well-documented, caution is advised for individuals with compromised immune systems or those on immunosuppressive medications. Additionally, individuals with severe yeast allergies should avoid using EpiCor, and pregnant or breastfeeding women are encouraged to consult a healthcare provider prior to use.

Dosage

The recommended dosage for EpiCor generally ranges from 500 mg to 1000 mg per day, with 500 mg considered an appropriate starting point. There is currently no established minimum effective dose, and higher dosages (exceeding 1000 mg) have not been extensively studied. EpiCor can be taken at any time, though consumption with meals is suggested to enhance absorption. It is available in both capsule and powder forms, providing flexibility for user preference. While no definitive upper limits have been established, excessive intake should be approached with caution.

FAQs

Is EpiCor safe?

EpiCor is generally safe for most people, but those with yeast allergies or compromised immune systems should be cautious.

When should I take EpiCor?

EpiCor can be taken at any time, but it's recommended to take it with meals for better absorption.

What benefits should I expect?

Users may experience a reduction in upper respiratory tract infections and improved gut health after consistent use.

Is EpiCor a live yeast?

No, EpiCor is a dried fermentate and does not carry the same risks as live yeast cultures.

Research Sources

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277533/ – This study examines the effects of EpiCor on immune function and gut health. It highlights the significant reduction in URTIs in healthy adults and discusses the role of its bioactive components in modulating immune responses.
https://www.frontiersin.org/articles/10.3389/fmicb.2020.00224/full – This article provides a comprehensive review of EpiCor, detailing its composition, mechanisms of action, and clinical efficacy. It notes the positive effects on gut microbiota and immune modulation.