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Goji Extract

Also known as: Lycium barbarum L., Goji berry, Wolfberry, Lycium barbarum

Overview

Lycium barbarum, commonly known as Goji berry or Wolfberry, is a plant native to Asia, particularly China. Its berries are highly valued for their rich nutritional profile, including polysaccharides, beta-carotene, and zeaxanthin. Goji extract is derived from these berries and is used as a dietary supplement to harness its potential health benefits. Primary applications include improving lipid profiles, supporting eye and skin health, and enhancing immune function due to its high antioxidant content. Research on Goji extract is considered to be at a moderate maturity level, with several systematic reviews and meta-analyses available, providing generally good quality evidence supporting its various health claims. It is available in various forms, including dried berries, juice, and concentrated extracts.

Benefits

Goji extract offers several evidence-based health benefits. A meta-analysis of 5 RCTs showed a significant decrease in triglyceride concentrations and an increase in high-density lipoprotein cholesterol (HDL-C) concentrations, suggesting potential benefits for lipid profiles. Additionally, a clinical trial indicated that Lycium barbarum mouthwash, when used with scaling and root planing, reduced plaque and gingival indices, demonstrating benefits for oral health. Some studies also suggest improvements in energy levels, focus, and mental acuity, although these findings require further validation. These benefits appear to be consistent across both healthy and unhealthy populations, although more research is needed to confirm the effects in unhealthy populations. The antioxidant properties of Goji extract also contribute to its general health benefits.

How it works

The health benefits of Lycium barbarum are primarily attributed to its antioxidant and polysaccharide components. These compounds work by reducing oxidative stress and inflammation within the body. Specifically, the polysaccharides and carotenoids in Goji berries interact with the cardiovascular system by influencing lipid metabolism, leading to improved lipid profiles. Additionally, they support the immune system by enhancing antioxidant defenses. While the exact molecular targets are not fully elucidated, it is believed that these components engage pathways related to lipid metabolism and antioxidant activity, contributing to the observed health benefits.

Side effects

Goji extract is generally considered safe for most people when consumed in moderation or as a supplement for up to three months. Common side effects are rare but may include allergic reactions and increased sensitivity to sunlight. No significant uncommon side effects have been consistently reported in the literature. Rare side effects primarily involve allergic reactions and photosensitivity. It is advised to exercise caution when using Goji extract, especially for individuals on blood thinners or diabetes medications, as potential interactions may occur. Individuals with known allergies to Lycium barbarum or its components should avoid its use. Pregnant or breastfeeding women should consult healthcare providers before using Goji extract supplements due to limited safety data in these populations.

Dosage

The minimum effective dose of Goji extract is not definitively established, but studies have used doses ranging from 14 grams of dried berries to 300 mg of extract per day. Optimal dosages typically fall within this range. There is no established maximum safe dose, but prolonged use beyond three months has not been extensively studied. Consistency in daily intake is recommended, and the timing of administration does not appear to be critical. Both dried berries and extracts have been used in studies, with extracts potentially offering higher bioavailability of active components. A balanced diet may enhance the absorption and utilization of Goji extract components.

FAQs

Is Goji extract safe to use?

Goji extract is generally safe, but individuals should be aware of potential allergic reactions and interactions with medications, especially blood thinners and diabetes medications. Consult a healthcare provider if you have concerns.

When is the best time to take Goji extract?

Consistent daily intake is recommended, but the timing of administration is not critical. Choose a time that is convenient for you to ensure regular consumption.

What results can I expect from taking Goji extract?

Improvements in lipid profiles and oral health can be expected, along with potential enhancements in energy and mental acuity. However, individual results may vary.

Is Goji extract a cure-all?

No, Goji extract is not a cure-all. It should be used as part of a balanced health regimen that includes a healthy diet and regular exercise.

Research Sources

https://journals.lww.com/md-journal/fulltext/2021/12100/efficacy_of_lycium_barbarum_l__on_plasma_lipid.73.aspx – This systematic review and meta-analysis examined the effects of Lycium barbarum on plasma lipid concentrations. The analysis of 5 RCTs involving 259 subjects found that supplementation significantly decreased triglyceride concentrations and increased high-density lipoprotein cholesterol concentrations, suggesting potential benefits for lipid profiles.
https://f1000research.com/articles/12-302 – This clinical trial assessed the efficacy of Lycium barbarum mouthwash in treating periodontitis. The study found that the mouthwash, when used with scaling and root planing, reduced plaque index, gingival index, and bleeding on probing, indicating benefits for oral health, although the effects were comparable to chlorhexidine mouthwash.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10545344/ – This study provides supporting evidence for the benefits of Lycium barbarum. It highlights the antioxidant properties and potential improvements in energy, focus, and mental acuity associated with its consumption, although further research is needed to validate these findings.
https://www.medicalnewstoday.com/articles/322693 – This article provides a general overview of Goji berries, discussing their nutritional content and potential health benefits. It notes that Goji berries are high in antioxidants and may support immune function, eye health, and skin health, while also cautioning about potential side effects and interactions.