Get Your Personalized Supplement StackSupplement Stack Quiz

Lycii

Also known as: Lycium barbarum L., Fructus lycii, Goji berry, Wolfberry, Lycium barbarum

Overview

Lycium barbarum, commonly known as goji berry or wolfberry, is a plant native to Asia, particularly China. Its fruit has been used for centuries in traditional medicine and as a dietary supplement. The berries are rich in antioxidants, vitamins, and minerals, making them a popular choice for those seeking to improve their overall health. Goji berries are particularly high in carotenoids, including zeaxanthin, which is beneficial for eye health. They also contain flavonoids and polysaccharides, which contribute to their potential health benefits. Lycium barbarum is available in various forms, including fresh or dried fruit, juice, and extracts. Research suggests potential benefits for vision, immune function, lipid metabolism, and overall antioxidant status, though more rigorous studies are needed to confirm these effects.

Benefits

Lycium barbarum has shown potential benefits in several areas. A meta-analysis indicated that supplementation can significantly decrease triglycerides and increase HDL cholesterol levels, suggesting a positive impact on lipid profiles. This may be particularly beneficial for individuals with dyslipidemia. Additionally, research suggests potential benefits for retinal health and diabetic retinopathy, although more RCTs are needed to confirm these outcomes. The antioxidant properties of Lycium barbarum may also help reduce oxidative stress, contributing to overall health and well-being. While these findings are promising, the clinical significance of some changes is moderate, and further research is necessary to establish long-term benefits and optimal usage guidelines.

How it works

Lycium barbarum's mechanism of action is primarily attributed to its antioxidant properties and potential modulation of lipid metabolism pathways. The polysaccharides and carotenoids present in the berries may influence cellular signaling pathways related to inflammation and oxidative stress. Specifically, compounds like zeaxanthin may protect the retina from oxidative damage. The interaction with body systems includes potential benefits for the cardiovascular and visual systems. While the exact absorption and bioavailability of bioactive compounds are not extensively studied, it is believed that these compounds are absorbed in the gastrointestinal tract, contributing to their systemic effects.

Side effects

Lycium barbarum is generally considered safe when consumed in moderation. Common side effects are not well-documented, but some individuals may experience gastrointestinal upset. Uncommon side effects include the potential for allergic reactions in sensitive individuals. Due to its effects on blood sugar and lipid profiles, Lycium barbarum may interact with anticoagulants or diabetes medications, requiring caution in individuals taking these drugs. It is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Individuals with bleeding disorders or those taking anticoagulant medications should exercise caution. As with any supplement, it is important to consult with a healthcare provider before use, especially if you have underlying health conditions or are taking other medications.

Dosage

While a minimum effective dose of Lycium barbarum is not well established, typical doses range from 10 to 30 grams per day. Optimal dosage ranges are not clearly defined, but higher doses may be more effective for certain benefits. The maximum safe dose is also not established, so high doses should be approached with caution. There are no specific timing recommendations for consumption. Lycium barbarum can be consumed as fresh or dried fruit, juice, or extracts. Bioavailability may vary based on the preparation method and individual factors. It is important to ensure proper identification and sourcing of Lycium barbarum products to avoid adulteration. As with any supplement, it is advisable to start with a lower dose and gradually increase as tolerated.

FAQs

Is Lycium barbarum safe to take with other medications?

Lycium barbarum may interact with anticoagulants and diabetes medications. Consult a healthcare provider before use, especially if you are taking other medications, to avoid potential adverse effects.

What are the expected benefits of taking Lycium barbarum?

Potential benefits include improvements in lipid profiles and antioxidant status. Some studies suggest benefits for retinal health, but more research is needed to confirm these effects.

How should Lycium barbarum be taken for best results?

There is no specific timing recommended, but consistent daily intake may be beneficial. Ensure proper identification and sourcing of Lycium barbarum products to avoid adulteration.

Are there any specific precautions I should be aware of?

If you are pregnant, breastfeeding, have bleeding disorders, or are taking anticoagulant medications, exercise caution and consult with a healthcare provider before using Lycium barbarum.

Is Lycium barbarum a cure-all for health issues?

No, Lycium barbarum is not a cure-all. Its benefits are generally supportive rather than therapeutic. It should be used as part of a balanced diet and healthy lifestyle.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/37773857/ – This meta-analysis of 5 trials with 259 subjects found that Lycium barbarum supplementation significantly decreased triglycerides and increased HDL cholesterol. The study suggests a potential benefit for lipid profiles, but notes limitations due to sample size and heterogeneity among the included studies, indicating a need for further research.
https://www.mdpi.com/2072-6643/13/1/246 – This systematic review highlights the potential benefits of Lycium barbarum in retinal health and diabetic retinopathy. While the review suggests promising outcomes, it also points out the lack of randomized controlled trials specifically addressing these benefits, indicating that more rigorous research is needed to confirm these effects.
https://journals.lww.com/md-journal/fulltext/2021/12100/efficacy_of_lycium_barbarum_l__on_plasma_lipid.73.aspx – This review protocol outlines a systematic review and meta-analysis aimed at assessing the effect of Lycium barbarum on plasma lipid concentration. The protocol adheres to PRISMA guidelines, suggesting a high potential for quality, but the review is not yet completed, so the findings are still pending.
https://onlinelibrary.wiley.com/doi/pdf/10.1155/2019/4615745 – This study investigates the protective effects of Lycium barbarum polysaccharides (LBPs) against retinal damage. The findings suggest that LBPs may have therapeutic potential for retinal diseases due to their antioxidant and anti-inflammatory properties, but further clinical trials are needed to confirm these effects in humans.
https://www.mdpi.com/2673-9976/40/1/1 – This review explores the potential of Lycium barbarum as a functional food for improving lipid and glucose metabolism, as well as reducing oxidative stress. The review highlights the bioactive compounds in goji berries and their potential mechanisms of action, suggesting that they may offer benefits for metabolic health.