Orange Extract
Also known as: Citrus sinensis, Citrus aurantium, Citrus reticulata, sweet orange, bitter orange, mandarin, orange extract, citrus extract
Overview
Orange extract primarily derives from *Citrus sinensis* (sweet orange) and is a dietary supplement utilized for various health benefits, including weight management, cardiovascular health, and skin enhancements. Rich in flavonoids and limonoids, orange extract contains bioactive compounds that exhibit potential antioxidative and anti-inflammatory properties. The extract is commonly used in capsule or tablet form, and its research maturity level is moderate, supported by several randomized controlled trials (RCTs) and meta-analyses, albeit with variable evidence quality. While some studies demonstrate significant efficacy, others yield inconclusive results, necessitating further investigation into its health effects. Overall, it provides a promising addition to health regimens, particularly for individuals seeking to manage their weight and enhance skin health.
Benefits
Evidence suggests that orange extract has several benefits: 1. Weight Management: Research indicates that *Citrus sinensis* supplementation may lead to reductions in body weight, BMI, and waist circumference, with some trials noting clinically significant results. 2. Cardiovascular Health: Certain studies report lowered LDL cholesterol levels among participants using the extract; however, findings are inconsistent, warranting caution. 3. Skin Health: Meta-analyses indicate improved skin hydration and reduced transcutaneous water loss from citrus fruit extracts. Overweight individuals may benefit most from its weight management properties, although results vary by study regarding effectiveness and clinical significance.
How it works
Orange extract's beneficial effects may stem from its bioactive compounds, including flavonoids and limonoids, which influence metabolic processes and cardiovascular health. These compounds potentially enhance fat oxidation and lipid metabolism through interactions with metabolic enzymes and inflammatory pathways. The extract's ability to modulate digestive system function may also contribute to its weight management and cardiovascular benefits, although specific bioavailability data remain limited.
Side effects
Orange extract is generally regarded as safe when used in moderation. Common side effects (occurring in over 5% of users) include gastrointestinal upset. Uncommon side effects (1-5%) may encompass allergic reactions and unspecified interactions with medications, particularly blood thinners and diabetic drugs. Rare side effects (<1%) are not well-documented. Care should be exercised by individuals allergic to citrus. Pregnant or breastfeeding women are advised to consult healthcare providers before use. No severe adverse events have been conclusively linked to orange extract, but caution is advised in higher doses due to the absence of defined maximum limits.
Dosage
An optimal dosage range for *Citrus sinensis* extracts typically falls between 0.5 to 1 gram per day. However, the minimum effective dose remains unclear and may vary based on individual studies. While no specific timing is recommended for administration, caution is advised when exceeding recommended amounts, since maximum safe dosages are not well defined. The extract is commonly available in capsules or tablets, and individual metabolism and dietary intake may influence absorption efficacy.
FAQs
Is orange extract safe to use?
Generally, orange extract is considered safe when taken in moderate amounts, but individuals should watch for gastrointestinal issues or allergic reactions.
When is the best time to take orange extract?
There are no specific timing recommendations; follow individual product instructions for best results.
Can orange extract help with weight loss?
Some studies suggest it may support weight management, particularly in overweight individuals, but results can vary.
Is orange extract a substitute for a healthy diet?
No, it should supplement a balanced diet and not replace comprehensive nutritional strategies.
What are common side effects of orange extract?
Common side effects include gastrointestinal upset; allergic reactions are also possible though less frequent.
Research Sources
- https://academic.oup.com/nutritionreviews/article/82/9/1292/7272715?login=false – This review highlights the effects of *Citrus sinensis* on muscle and fat composition, noting moderate improvements in body composition alongside some limitations in scope.
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1232229/full – This meta-analysis explores the impact of various fruit extracts, including citrus, on skin hydration, revealing significant positive outcomes in skin moisture retention.
- https://examine.com/supplements/bitter-orange/ – This source reviews *Citrus aurantium*, discussing its weight control effects and caution regarding potential risks associated with its extracts.
- https://scholar.unhas.ac.id/en/publications/the-safety-and-efficacy-of-citrus-aurantium-bitter-orange-extract – An investigation into the safety and efficacy of *Citrus aurantium* extracts emphasizing its metabolic and cardiovascular potentials alongside safety considerations.
- https://pubmed.ncbi.nlm.nih.gov/36235672/ – This research delves into the overall benefits of orange extracts, including body composition analyses and metabolic enhancements, citing variable evidence across different studies.
Supplements Containing Orange Extract
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