Meratrim Proprietary Blend
Also known as: Sphaeranthus indicus, Garcinia mangostana, Meratrim Proprietary Blend, Meratrim
Overview
Meratrim is a proprietary blend of extracts from the flowers of *Sphaeranthus indicus* and the fruit rinds of *Garcinia mangostana*, traditionally used in Ayurvedic and Southeast Asian medicine. Primarily marketed for weight management and enhancing body composition, this supplement features a 3:1 ratio of *Sphaeranthus indicus* to *Garcinia mangostana*. While clinical trials, including randomized controlled trials (RCTs) and animal studies, indicate promising benefits in weight loss and lipid profile improvement, further research is necessary to confirm these findings and evaluate long-term efficacy. The supplement is typically prepared in capsule form and requires adherence to a balanced diet and regular exercise for optimal results.
Benefits
Meratrim has demonstrated significant weight loss benefits, with a 16-week RCT showing an average reduction in body weight of 5.09 kg compared to 1.1 kg in the placebo group (p < 0.0001). Other notable findings include improvements in BMI, waist size, and hip circumference. Additionally, Meratrim has been linked to favorable changes in lipid profiles, reducing LDL cholesterol, triglycerides, and total cholesterol. The observed benefits are most prominent in healthy overweight and obese populations, with significant effect sizes noted in multiple studies, suggesting its potential as an effective aid in weight management.
How it works
Meratrim functions primarily by inhibiting fat accumulation and enhancing non-shivering thermogenesis in brown adipose tissue. It also appears to inhibit hepatic de novo lipogenesis, effectively altering lipid metabolism and adipose tissue function. Although specific molecular targets remain to be defined, these actions contribute to an increase in energy expenditure and a reduction in body fat stores.
Side effects
Meratrim is generally recognized as safe and well-tolerated at recommended dosages of 800 mg per day, divided into two doses. In clinical studies, no common side effects (>5%) were reported, and uncommon or rare side effects (<5%) were not documented either. Although no specific drug interactions have been recorded, consultation with a healthcare provider is recommended before commencing use. Caution is advised for pregnant or breastfeeding women due to insufficient safety data regarding these populations, and the safety in children and individuals with chronic diseases remains unclear.
Dosage
The recommended dosage of Meratrim is 800 mg per day, ideally taken in two 400 mg doses before meals, such as 30 minutes prior to breakfast and dinner. This dosing regimen is based on studies highlighting its efficacy. While animal studies suggest tolerability at higher doses, specific maximum safe doses for human use have not been established. For better absorption, it is typically advised to take Meratrim with meals as part of a holistic approach to weight management.
FAQs
How should Meratrim be taken for best results?
Take 400 mg twice daily, 30 minutes before meals, as part of a comprehensive weight management plan that includes diet and exercise.
Is Meratrim safe?
Yes, Meratrim is considered safe at the recommended dosages, but long-term effects and interactions need more study.
When can I expect to see results?
Participants in studies noted significant weight loss and improvements in body composition and lipid profiles after 8 to 16 weeks.
Can I take Meratrim if I'm pregnant?
Caution is advised; the safety of Meratrim during pregnancy and breastfeeding has not been established.
Is Meratrim a quick fix for weight loss?
No, Meratrim should be part of a lifestyle change involving diet and exercise for sustained weight management.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/27558585/ – This RCT with 60 healthy overweight participants found significant reductions in body weight and waist circumference after 16 weeks of Meratrim use, with favorable changes in lipid profiles evident.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.964495/full – An animal study that confirmed Meartrim's capacity to reduce body weight and improve lipid profiles in obese mice, elucidating its mechanism of action but noting the limitations of translating findings to humans.
- https://www.mdpi.com/2304-8158/13/18/3013 – This review analyzed RCTs of Meratrim, highlighting significant efficacy for weight loss while emphasizing the need for additional independent research to validate findings.
- https://www.healthline.com/nutrition/does-meratrim-work – Healthline provides a comprehensive overview of the current understanding of Meratrim, noting its potential benefits and the importance of integrating its use within a broader weight management strategy.
- https://www.mdpi.com/1648-9144/54/6/109 – This systematic analysis evaluates studies on Meratrim, concluding that while evidence supports weight management effectiveness, further long-term studies are necessary for conclusive results.
Supplements Containing Meratrim Proprietary Blend

Metabolic Management Pack
Douglas Laboratories

Maximum-Strength Adiponectin Activation Formula with Meratrim 400 mg
Swanson Best Weight-Control Formulas

Tone & Define
GNC Total Lean Advanced

SLIMit
Health Direct

Metabolic Management Pack
Douglas Laboratories

Meratrim Platinum+
BioGenetic Laboratories

Oxotrim With Meratrim
NewtonEverett

Advanced Anti-Adipocyte
Life Extension
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