Tone & Define
GNC Total Lean Advanced
Overview
The effectiveness of GNC Total Lean Advanced Tone & Define is moderate, relying on a combination of proprietary blends and individual extracts. While key ingredients like Meratrim, Blood Orange Extract, and Garcinia Cambogia have shown some statistically significant, albeit modest, benefits in weight and body composition studies, the overall efficacy is limited by the proprietary nature of the blends, which prevents full disclosure of individual ingredient dosages. EGCG is present but at a dose lower than typically studied for significant metabolic effects.
The Good
Low stimulant content (18 mg caffeine per serving) minimizes jitters and sleep interference.
Contains Meratrim and Blood Orange Extract, which have clinical studies supporting modest weight loss and body composition improvements.
Includes EGCG and various citrus extracts known for their antioxidant properties.
The Bad
Proprietary blends (Citri-Sculpt and Metabolic Activation Blend) hide individual ingredient dosages, making it difficult to verify research-backed amounts for all components.
EGCG dose (22.2 mg per serving) is significantly lower than doses typically shown to be effective in clinical studies (200-400 mg).
Garcinia Cambogia offers only a small, clinically modest weight loss benefit.
Is it for you?
Best For: Individuals seeking weight management support, those focused on body composition
Skip If: You are pregnant, nursing, or have pre-existing medical conditions without consulting a doctor
Ingredients Analysis
Egcg
22.2 mgHow to Use
Follow dosage instructions on product label, typically taken with water.
Daily
Morning & Evening
With meals
Who Should Use This
Best For:
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