Nem
Also known as: Natural Eggshell Membrane, NEM
Overview
Natural Eggshell Membrane (NEM) is a dietary supplement derived from eggshell membranes, primarily used to promote joint health. It is a natural source of glycosaminoglycans (GAGs) and proteins, which are critical components for maintaining healthy joints and connective tissues. NEM is commonly used to alleviate pain and stiffness in individuals suffering from osteoarthritis. Its mechanisms of action include enhancing cartilage repair and reducing inflammation, although the precise molecular interactions remain unclear. NEM is typically available in vegetarian capsules, and research supports its effectiveness in reducing specific symptoms of joint degradation.
Benefits
NEM has demonstrated benefits for individuals with osteoarthritis, with clinical studies indicating a significant reduction in pain (up to 66.4%) and stiffness (up to 59.7%) within a 30-day period. Improvements may start within 10 days of consistent use. Animal studies suggest potential benefits for other types of inflammatory arthritis, but more rigorous studies are needed to solidify these findings, especially across diverse populations. The strength of evidence varies, highlighting the need for further research to confirm these effects.
How it works
NEM primarily functions by supplying essential glycosaminoglycans, which are vital for maintaining and repairing cartilage and connective tissue in joints. It may enhance the body's ability to regenerate these tissues while simultaneously reducing inflammatory responses linked to arthritic conditions. The exact biological pathways involved in NEM's action remain largely undefined, though its interactions with joint components like cartilage suggest enhancement of structural integrity.
Side effects
NEM is generally regarded as safe, with very few adverse effects reported in clinical studies. Common side effects have not been consistently documented, and uncommon or rare side effects have also shown minimal occurrence. However, caution is warranted for individuals with egg allergies, as NEM is derived from eggshells. While there are no noted significant drug interactions, individuals taking other medications should consult healthcare professionals prior to use, particularly pregnant or breastfeeding women who should seek medical guidance before incorporating NEM into their regimen.
Dosage
The recommended dosage for NEM is typically 500 mg taken once daily, considered the minimum effective dose. While there is no well-established upper limit for safe consumption, adherence to recommended dosages is advised. For optimal results, NEM should be taken consistently at the same time each day. The absorption characteristics of NEM have not been deeply studied, indicating a potential area for further research.
FAQs
Is NEM safe to use?
NEM is generally considered safe for most individuals, but those with egg allergies should be cautious and consult a healthcare provider before use.
How long does it take to see results?
Most users may notice significant reductions in pain and stiffness within a few weeks of consistent use, although individual results may vary.
Can I take NEM with other medications?
While no major drug interactions are documented, it is advisable to consult a healthcare professional before combining NEM with other medications.
Is NEM a cure for osteoarthritis?
NEM is not a cure for osteoarthritis but may help manage symptoms such as pain and stiffness, improving overall joint function.
What is the optimal way to take NEM?
Taking NEM consistently once a day is recommended for the best results, preferably at the same time each day to maintain stable levels.
Supplements Containing Nem
Recommended Articles

Essential Nutrients for Health: What You Need
A balanced diet including a variety of key nutrients is crucial for health maintenance and disease prevention.

Boost Nutrient Absorption with Vitamin C
Vitamin C significantly improves the absorption of iron, calcium, and antioxidants, optimizing overall health.

Best Iron Supplements: Less Side Effects, Better Absorption
Ferrous sulfate, gluconate, and fumarate are top oral iron supplements, with vitamin C enhancing absorption and certain practices reducing side effects.

Avoid These Food Combos for Better Health
Certain foods and supplements should not be consumed together due to interactions that can hinder nutrient absorption or pose health risks.