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Orange Fruit Extract

Also known as: Orange Fruit Extract, Orange Juice Extract, Sweet Orange Extract, *Citrus sinensis*

Overview

Orange Fruit Extract is derived from sweet oranges and predominantly from *Citrus sinensis*, known for its rich composition of flavonoids, specifically hesperidin. This extract is commonly used in dietary supplements for its potential health benefits, including weight management and improving lipid profiles. The flavonoids present offer antioxidant properties that may contribute positively to cardiovascular health. While research into the effectiveness of orange fruit extract has matured with the support of several randomized controlled trials (RCTs) and meta-analyses, the quality and consistency of evidence vary. It is commercially available in various forms, including juices and concentrated extracts, making it accessible for those looking to enhance their nutritional intake.

Benefits

Evidence suggests several benefits associated with Orange Fruit Extract: 1) Weight Management: Some RCTs show that supplementation can lead to reductions in body weight, BMI, and waist circumference. These benefits, however, have varied outcomes and may depend on individual responses. 2) Lipid Profile Improvement: Studies, particularly a systematic review, demonstrate that daily intake of orange juice (especially over 500 mL) significantly lowers LDL-C levels and increases HDL-C, serving as a promising approach for individuals with dyslipidemia. 3) Antioxidant and Anti-inflammatory Effects: Although direct human studies are lacking, flavonoids are acknowledged for their general capability to combat oxidative stress. The most pronounced effects seem to be in overweight populations, with some studies yielding significant effect sizes for lipid profile improvements.

How it works

Orange Fruit Extract's mechanisms primarily involve the action of flavonoids like hesperidin on lipid metabolism. These compounds may enhance lipid profiles by modulating enzymes related to lipid digestion and absorption. Moreover, they contribute to systemic antioxidant defenses, reducing oxidative stress and inflammation, and thus positively influencing cardiovascular health. Hesperidin and other flavonoids can also interact with metabolic systems, suggesting multifaceted roles that may extend beyond simple antioxidant effects.

Side effects

Orange Fruit Extract is generally recognized as safe when consumed appropriately. Common side effects are infrequent, but sensitive individuals may experience gastrointestinal issues. While severe adverse effects are rare, there is potential for interactions with medications that influence blood sugar or lipid levels due to the natural sugars present in orange juice. Precautions should be taken for individuals with diabetes to avoid spikes in blood glucose levels. Pregnant and breastfeeding women should seek medical advice before starting supplementation. Regular monitoring of dietary intake is advisable, particularly in juice forms due to sugar content, which can lead to greater caloric intake.

Dosage

For optimal benefits, the minimum effective dose of Orange Fruit Extract is not well defined; however, intake of over 500 mL of orange juice per day has shown benefits in lipid profile management. Dosing varies depending on the supplement form (juice vs. extract), and bioavailability may differ significantly based on preparation methods. As high juice consumption can lead to excess sugar intake, recommendations for maximum safe doses have not been firmly established. Timing of doses is not specified; instead, consistent daily intake might be beneficial. Individuals should consult healthcare professionals for personalized dosage advice, especially if they have underlying health conditions.

FAQs

Is Orange Fruit Extract safe?

Yes, it is generally considered safe for most people. However, those with diabetes should monitor sugar intake.

What are the expected results?

Results can vary; benefits for weight and lipid profiles are observed but not guaranteed for everyone.

How should I take Orange Fruit Extract?

Consult a healthcare provider and ensure your product is from a reputable source; specific timing isn't recommended.

Can I use it if I'm pregnant?

Consult your healthcare provider before using any supplement while pregnant or breastfeeding.

Does it work for every individual?

Not necessarily; effectiveness can differ based on individual factors and lifestyle.

Research Sources

https://academic.oup.com/nutritionreviews/article/82/9/1292/7272715?login=false – This randomized controlled trial demonstrated the effects of orange extract supplementation on body weight and BMI in individuals with mild obesity, indicating promising weight management potential.
https://www.cambridge.org/core/journals/journal-of-nutritional-science/article/orange-juice-intake-and-lipid-profile-a-systematic-review-and-metaanalysis-of-randomised-controlled-trials/520EBD5C16FCFCD80810712DC25B3E06 – This systematic review and meta-analysis evaluated the impact of orange juice consumption on lipid profiles, finding that significant reductions in LDL-C were associated with daily intakes over 500 mL.
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1232229/full – The study indicated that supplementation with orange extract led to improved body composition, showing increases in muscle mass and reductions in fat mass among adults.