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Organic Schisandra Extract

Also known as: Schisandra, Omija, Five-Flavor Berry, *Schisandra chinensis*

Overview

*Schisandra chinensis*, commonly known as Schisandra or Five-Flavor Berry, is a herbaceous plant native to East Asia, particularly valued for its berries in traditional herbal medicine. Renowned for its adaptogenic properties, Schisandra is believed to help the body adapt to stress and improve overall resilience. The plant is rich in lignans, with Schisandrin A being a primary active component linked to its diverse therapeutic effects. Common applications include enhancing physical performance, promoting mental clarity, supporting immune function, and managing blood sugar levels. Despite promising findings in antioxidant and anti-inflammatory research, clinical evidence primarily stems from animal studies and limited human trials, indicating a necessity for further placebo-controlled studies to substantiate its efficacy and safety in various population groups.

Benefits

Research suggests several key benefits of *Schisandra chinensis*. Primarily, it may aid in glycemic control, as shown in a study involving type 2 diabetes individuals where it enhanced glucose metabolism. Evidence also supports its role in reducing oxidative stress and inflammation, crucial for overall health. Additionally, *Schisandra* may enhance physical performance and decrease fatigue; however, this effect is less consistently validated across studies. Limited evidence points to significant benefits especially for populations dealing with oxidative stress or those diagnosed with diabetes. Effect sizes vary, and comprehensive studies are necessary to understand the clinical significance of these benefits fully. Also, notable increases in health indicators may be observed after sustained supplementation over several weeks.

How it works

*Schisandra chinensis* exerts its effects through various biological pathways including antioxidant and anti-inflammatory mechanisms. The active compound Schisandrin A particularly influences insulin sensitivity and glucose uptake, facilitating better glucose metabolism. This complex interaction also affects the immune system, potentially modulating inflammation and improving overall resilience against stressors. The compounds are generally absorbed in the body, though their bioavailability may vary, affecting their overall efficacy.

Side effects

While *Schisandra chinensis* is largely considered safe for most individuals, it is associated with some common side effects such as gastrointestinal upset. Rarely, allergic reactions may occur, although documentation is scarce. Drug interactions are a consideration, notably with blood thinners or diabetes medications due to its glucose-modulating effects. It is advisable for pregnant and breastfeeding women to avoid the supplement due to insufficient safety data. Caution should be exercised in individuals with severe health conditions or those on specific medications without prior consultation with a healthcare provider. Overall, comprehensive safety data remains limited, reinforcing the need for careful monitoring and consultation when using this supplement.

Dosage

The optimal dosage of *Schisandra chinensis* is not firmly established, but ranges from 500 mg to 1,000 mg daily are commonly cited based on various studies. Initially, a minimum effective dose of around 500 mg has shown some positive results, particularly for glycemic control. Higher doses should be approached cautiously, as maximum safe limits are not thoroughly defined in existing literature. The supplement is best taken with meals to mitigate gastrointestinal issues, and taking it consistently can help maintain potential benefits. Absorption may be enhanced when taken with fatty meals, further optimizing the effects of the active compounds.

FAQs

Is *Schisandra chinensis* safe to use?

Generally, yes. It's considered safe for most people, but should be avoided during pregnancy and breastfeeding due to lack of safety data.

How should I take *Schisandra chinensis*?

It is recommended to consume it consistently, typically with meals, to enhance absorption and reduce potential gastrointestinal upset.

Can *Schisandra chinensis* interact with other medications?

Yes, particularly with blood thinners and diabetes medications, due to its effects on glucose metabolism.

What results can I expect from taking *Schisandra chinensis*?

Results vary; improvements in energy, stress resilience, and glycemic control may take several weeks of consistent use.

Is it a cure for health problems?

No, it is not a substitute for medical treatment but may serve as a complementary approach when used with a balanced lifestyle.

Research Sources

https://www.mdpi.com/2072-6643/14/15/3159 – This randomized double-blind trial examined the effects of an Omija extract on glycemic control in type 2 diabetes patients, revealing significant improvements in fasting plasma glucose levels.
https://jtd.amegroups.org/article/view/35966/html – This study highlighted the antioxidant effects of Schisandrin A, noting its protective properties against oxidative stress in lung epithelial cells through modulation of specific antioxidant markers.
https://www.mdpi.com/1660-4601/17/7/2475 – Investigation into the effect of *Schisandra chinensis* on muscle strength and fatigue found no significant improvements compared to placebo in the subjects studied.
https://journals.sagepub.com/doi/full/10.1177/1934578X20970855 – This overview examines the pharmacological properties of *Schisandra chinensis*, emphasizing the need for further research to validate its medicinal applications.
https://www.researchgate.net/publication/5336030_Pharmacology_of_Schisandra_chinensis_Bail_An_overview_of_Russian_research_and_uses_in_medicine – This source reviews Russian research on *Schisandra chinensis*, discussing its traditional uses and emerging pharmacological evidence, although caution is advised due to varying research quality.