Paprika
Also known as: Paprika, Sweet Pepper, Bell Pepper, *Capsicum annuum L.*
Overview
Paprika is a spice derived from the dried fruit of the sweet pepper plant (*Capsicum annuum L.*) and is renowned for its vibrant red color and diverse carotenoid content, including capsanthin, β-carotene, β-cryptoxanthin, and zeaxanthin. As a carotenoid-rich dietary supplement, paprika is lauded for its antioxidant properties, which can potentially mitigate cellular oxidative damage. In addition to its culinary applications, paprika's carotenoids are studied for their health benefits, which include improved bone quality and reduced cancer risk. The body of research on paprika carotenoids is expanding, showcasing randomized controlled trials and meta-analyses that underline their importance as functional foods.
Benefits
Evidence-based benefits of paprika include significant improvements in bone health, particularly in postmenopausal women, where a study demonstrated that supplementation with paprika carotenoid extract resulted in reduced markers of bone resorption (TRACP-5b) over 24 weeks. Furthermore, a meta-analysis found that high dietary intake of carotenoids, including those from paprika, correlates with lower risks of several cancers, such as gastric and colorectal cancers, with notable odds ratios indicating protective effects. Overall, postmenopausal women have shown notable benefits from paprika supplementation regarding bone quality maintenance.
How it works
Paprika carotenoids function primarily as antioxidants, safeguarding cells against oxidative stress and damage. They exert effects on bone metabolism by inhibiting the activity of osteoclasts, the cells responsible for bone resorption, leading to decreased bone loss. These carotenoids interact with key enzymes involved in bone turnover and may influence immune responses through their antioxidant capabilities, thereby supporting overall skeletal health.
Side effects
Paprika carotenoids are generally safe for consumption in dietary amounts, with limited data identifying common side effects (>5%). Uncommon side effects (1-5%) and rare side effects (<1%) are not well-documented, indicating a favorable safety profile. There is no strong evidence of drug interactions, although caution is recommended when taking with other antioxidants or medications that could interact with carotenoids. Particularly vulnerable groups, such as pregnant or breastfeeding women, should seek medical advice prior to supplementation. Individuals with known allergies to peppers or certain medical conditions should also consult healthcare professionals before use.
Dosage
The minimum effective dose of paprika carotenoid extract (PCE) for bone health is 20 mg per day, approximately equivalent to 1.4 mg of total carotenoids. This dosage corresponds to results observed in studies focusing on bone resorption markers. While optimal dosage ranges are not extensively studied beyond this threshold, maintaining continuous daily supplementation is advised based on current findings. Notably, the absorption of these carotenoids may be enhanced when consumed with dietary fats, as they are lipophilic compounds. No defined maximum safe dose exists, necessitating further investigation into upper limits of effectiveness and safety.
FAQs
Are paprika carotenoids safe?
Yes, paprika carotenoids are generally considered safe when consumed as part of a diet, though long-term high-dose effects are not fully understood.
How should paprika supplements be taken?
Daily supplementation of paprika carotenoid extract is recommended based on research findings.
What benefits can I expect from paprika supplementation?
Expected benefits include improved bone health and potential cancer risk reductions, although individual results may vary.
Are all carotenoids the same in terms of benefits?
No, specific carotenoids in paprika have unique effects that differ from other carotenoids.
Research Sources
- https://foodandnutritionresearch.net/index.php/fnr/article/view/4565 – This study investigated the effects of paprika carotenoid supplementation on bone turnover in postmenopausal women, revealing significant reductions in bone resorption markers (TRACP-5b) over 24 weeks, supporting the potential of paprika in maintaining bone health.
- https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effects-of-capsaicin-intake-on-weight-loss-among-overweight-and-obese-subjects-a-systematic-review-and-metaanalysis-of-randomised-controlled-trials/AF1C3A4331A35BA12CE925B0B56818B8 – This systematic review evaluated the effects of capsaicin, a related compound in peppers, on weight loss, highlighting modest effects across various studies but with significant considerations regarding study heterogeneity.
- https://jmla.pitt.edu/ojs/jmla/article/download/1223/1368 – A comprehensive meta-analysis exploring the relationship between dietary carotenoid intake and cancer risk indicated significant protective effects against several types of cancer correlated with higher dietary carotenoid consumption, including those found in paprika.
- https://www.mdpi.com/2304-8158/13/9/1321 – This source presented an umbrella meta-analysis demonstrating that high dietary intake of carotenoids, including from paprika, is linked to a reduced risk of various cancers, showcasing significant odds ratios for protective outcomes.
- https://training.cochrane.org/handbook/current/chapter-10 – The Cochrane Handbook provides methodological standards for conducting systematic reviews and meta-analyses, underscoring the significance of high-quality evidence in evaluating antioxidant supplements like paprika.
Supplements Containing Paprika

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Systemic Formulas

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