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Placenta

Also known as: Placenta, Placenta Extract, Placental Extract

Overview

Placenta extract, derived from the organ that develops in the uterus during pregnancy, is used as a dietary supplement. Typically sourced from bovine or porcine placentas, it is rich in proteins, hormones, and growth factors. Historically, it has been used in traditional medicine for purported anti-aging and hormonal balance benefits. However, the scientific evidence supporting these claims is limited, with few high-quality studies available. The research maturity level is low, and the quality of available evidence is generally weak. Therefore, caution is advised when considering placenta extract as a supplement due to the lack of robust scientific validation.

Benefits

There is limited evidence supporting specific health benefits of placenta supplements. Most claims are anecdotal or based on traditional use rather than rigorous scientific studies. Some proponents suggest benefits for skin health and hormonal balance, but these are not well-supported by scientific evidence. No specific population benefits have been clearly established through high-quality research. Due to the lack of robust studies, effect sizes and clinical significance cannot be reliably determined. The time course of any potential benefits is unknown due to the scarcity of systematic research.

How it works

The potential mechanisms of action for placenta supplements are speculative and may involve hormonal and growth factor interactions, but these are not well-studied. The interaction with body systems is not clearly understood and requires further research. There are no well-documented molecular targets for placenta supplements. The absorption and bioavailability of placenta-derived compounds are also not well-characterized. Further research is needed to elucidate the precise mechanisms by which placenta extract might exert any potential effects.

Side effects

The safety of placenta supplements is not well-established, particularly concerning long-term use or potential contaminants. There is insufficient data to determine common, uncommon, or rare side effects. Potential drug interactions are not well-studied. Contraindications are not clearly established but may include pregnancy or certain medical conditions. Special considerations for pregnant women, children, or individuals with certain health conditions are not well-defined. Due to the lack of comprehensive safety data, caution is advised, and consultation with a healthcare provider is recommended before use.

Dosage

There is no established minimum effective dose for placenta supplements due to the lack of rigorous studies. Optimal dosage ranges are not defined, and the maximum safe dose is unknown. Timing considerations for administration are not established. Form-specific recommendations (e.g., capsules, tablets) are not available. Factors affecting absorption are not well-studied. Required cofactors for optimal efficacy are not identified. Given the limited research, it is difficult to provide specific dosing guidelines, and users should exercise caution.

FAQs

Is placenta extract safe to use?

The safety of placenta extract is not well-established. Consult with a healthcare provider before use, especially if you have underlying health conditions or are pregnant or breastfeeding.

What are the expected benefits of taking placenta supplements?

Expected benefits are speculative and not supported by robust evidence. Claims related to anti-aging and hormonal balance lack strong scientific backing.

How should placenta supplements be taken?

There is no established timing or administration protocol. Due to the lack of research, specific recommendations cannot be made.

Are there any misconceptions about placenta supplements?

A common misconception is that placenta supplements have proven health benefits, which is not supported by high-quality research. Approach claims with caution.

What should I consider before taking placenta supplements?

Users should be cautious due to the lack of scientific evidence supporting benefits and safety. Consult healthcare providers before use to discuss potential risks and benefits.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/33573262/ – This study focuses on maternal nutritional supplements during pregnancy and their impact on infant health outcomes. While it highlights the importance of well-designed research in understanding supplement effects, it does not specifically address placenta supplements. The research underscores the need for rigorous studies to validate the benefits and safety of any supplement during pregnancy.
https://pubmed.ncbi.nlm.nih.gov/33358257/ – This research investigates the effects of maternal nutritional supplementation on birth weight and other neonatal outcomes. Similar to the previous study, it emphasizes the importance of evidence-based approaches to maternal nutrition but does not provide specific insights into placenta supplements. The study highlights the necessity of careful evaluation of supplement efficacy and safety during pregnancy.
https://academic.oup.com/humupd/article/30/4/410/7628277?login=false – This article discusses the impact of environmental exposures on human fertility. It underscores the importance of understanding how various factors can affect reproductive health. However, it does not directly address the use or effects of placenta supplements.
https://archive.is/M2Zwe – This archived webpage discusses the practice of placentophagy (consuming the placenta after birth). It highlights the lack of scientific evidence supporting the purported benefits of this practice. The information emphasizes the need for caution and further research before recommending placentophagy or placenta supplementation.
https://academic.oup.com/humupd/article/30/4/410/7628277?login=false – This article discusses the impact of environmental exposures on human fertility. It underscores the importance of understanding how various factors can affect reproductive health. However, it does not directly address the use or effects of placenta supplements.