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Proprietary Blend Of Sensoril

Also known as: Ashwagandha, Indian Ginseng, Winter Cherry, Sensoril, Withania somnifera

Overview

Ashwagandha, scientifically known as *Withania somnifera*, is an adaptogenic herb native to India, Africa, and the Middle East, and is traditionally used in Ayurvedic medicine for its ability to enhance stress adaptation by influencing both the endocrine and immune systems. The active constituents of ashwagandha, particularly in its standardized extract Sensoril, include withanolides, alkaloids, and glycosides, which provide therapeutic benefits. Recent research highlights Sensoril's efficacy in mitigating stress, anxiety, sleep disturbances, and enhancing cognitive function. Current evidence includes multiple randomized controlled trials and systematic reviews, illustrating a growing understanding of ashwagandha's benefits, although the quality of evidence varies due to differences in study methodologies and dosage levels used across studies.

Benefits

Ashwagandha offers several evidence-backed benefits: 1. **Stress Reduction**: A study showed a 62% reduction in stress using 125 mg/day of Sensoril. 2. **Anxiety Relief**: Systematic reviews reported significant reductions in anxiety levels across various scales. 3. **Sleep Improvement**: Meta-analysis indicated enhanced sleep quality for individuals with insomnia. 4. **Cognitive Function**: Higher doses (500 mg BID) were linked to improved mental performance and reaction times. 5. **Quality of Life**: Increased vitality and well-being are associated with supplementation. These effects are especially beneficial for chronically stressed adults and those suffering from insomnia, presenting noticeable results within 4 to 8 weeks.

How it works

Ashwagandha's mechanism of action involves modulation across multiple biological pathways, notably reducing cortisol levels and regulating the hypothalamic-pituitary-adrenal (HPA) axis, which plays a pivotal role in the body's response to stress. It interacts synergistically with the nervous, endocrine, and immune systems to produce adaptogenic effects, primarily via withanolides acting on key molecular targets related to stress and cognitive function. The aqueous formulation of the Sensoril extract enhances absorption, contributing to the overall effectiveness of ashwagandha.

Side effects

Ashwagandha, particularly in the Sensoril formulation, is generally considered safe with minimal side effects. Common side effects occurring in over 5% of users may include mild gastrointestinal discomfort. Less common side effects, reported in 1-5% of cases, consistently revealed no serious adverse consequences. Rare side effects occurring in less than 1% have not been documented. It is advisable to exercise caution when combining ashwagandha with medications affecting the HPA axis. Contraindications include its use during pregnancy and breastfeeding due to the lack of substantial safety data, as well as in individuals with autoimmune disorders who should consult a healthcare provider before starting supplementation due to potential immunomodulatory effects.

Dosage

The minimum effective dose of the Sensoril extract for stress management has been identified as 125 mg/day, with optimal dosages typically ranging from 125 mg to 500 mg daily. Although some studies have evaluated higher intake levels, up to 12,000 mg, such elevated doses are not generally recommended. The timing of administration can be flexible, but taking ashwagandha before bedtime may improve sleep outcomes. Sensoril, being a standardized aqueous extract, is preferred due to its established safety profile and efficacy. Absorption can be enhanced when taken with food and water.

FAQs

Is ashwagandha safe?

Generally, ashwagandha is safe, but individuals should consult healthcare providers, especially those in special populations.

When is the best time to take ashwagandha?

It can be taken anytime, but nighttime ingestion may be particularly beneficial for sleep enhancement.

What results can I expect?

Users typically experience reduced stress and anxiety, improved sleep quality, and potential enhancements in cognitive function.

Does ashwagandha cause dependency?

No, ashwagandha is an adaptogen, which means it assists the body in managing stress without causing dependency.

Research Sources

https://pubmed.ncbi.nlm.nih.gov – A collection of studies emphasizing ashwagandha's role in managing stress and anxiety, with evidence from randomized controlled trials pointing to significant benefits in mental and physical health.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937011/ – This systematic review discusses the efficacy of ashwagandha, highlighting its adaptogenic properties through various biological pathways, particularly its effect on cortisol levels and the HPA axis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153600/ – Meta-analysis findings on the effect of ashwagandha on sleep quality and cognitive function, indicating significant improvements in participants with insomnia and those experiencing cognitive challenges.